Collagen-Coated Bovine Bone in Peri-implantitis Defects: A Pilot Study on a Novel Approach

2016 ◽  
pp. 701-707 ◽  
Author(s):  
Shaun Rotenberg ◽  
Rob Steiner ◽  
Dimitris Tatakis
Keyword(s):  
Pilot Study ◽  
Bovine Bone ◽  
Novel Approach

scholarly journals Use of Continuous Positive Airway Pressure (CPAP) to Limit Diaphragm Motion—A Novel Approach for Definitive Radiation Therapy for Inoperable Pleural Mesothelioma: A Pilot Study

Biology ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 711
Author(s):  
Assaf Moore ◽  
Marc J. Kindler ◽  
Aaron Max Allen
Keyword(s):  
Pilot Study ◽  
Static Field ◽  
Normal Lung ◽  
Pleural Mesothelioma ◽  
Lung Dose ◽  
Lung Inflation ◽  
Novel Approach ◽  
Recent Developments ◽  
Ct Simulation ◽  
Dose Constraints

Malignant pleural mesothelioma (MPM) is a deadly disease and radiotherapy (RT) plays an important role in its management. Recent developments in technique have made it is possible to deliver RT to MPM in the intact lung. However, it is imperative to reduce normal lung doses. We present a pilot study examining the use of CPAP and VMAT radiotherapy to reduce toxicity when treating MPM, involving three consecutive patients with MPM, not amenable to surgery, who were treated according to Helsinki committee approval. Patients were simulated using four-dimentional CT simulation with the assistance of CPAP lung inflation, then were treated using both IMRT and VMAT techniques. Radiation lung dose was optimized based on accepted lung dose constraints. Patients were followed for toxicity as well as local control and survival. Results: Three patients were treated with CPAP-based IMRT treatment. These patients tolerated the treatment and DVH constraints were able to be met. The comparison plans among the four VMAT arcs and the IMRT static field treatment were able to accomplish the treatment planning objectives without significant advantages with either technique. The treatment combined with CPAP reduced the normal lung dose in MPM patients with intact lungs. This technique is worthy of further investigation.

scholarly journals Tissue adhesive—A novel approach to the securement of intra-arterial catheters? A randomised controlled pilot study

2014 ◽  
Vol 27 (1) ◽  
pp. 57
Author(s):  
M. Edwards ◽  
C. Rickard ◽  
I. Rapchuk ◽  
A. Corley ◽  
N. Marsh ◽  
...  
Keyword(s):  
Pilot Study ◽  
Tissue Adhesive ◽  
Novel Approach ◽  
Randomised Controlled

Banding Without Resection (Endoscopic Mucosal Ligation) as a Novel Approach for the Ablation of Short-Segment Barrett's Epithelium: Results of a Pilot Study

2007 ◽  
Vol 102 (8) ◽  
pp. 1640-1645 ◽  
Author(s):  
Edgardo Diaz-Cervantes ◽  
Antonio De-la-Torre-Bravo ◽  
Stuart Jon Spechler ◽  
Ernesto Torres-Durazo ◽  
Sergio Sobrino-Cossio ◽  
...  
Keyword(s):  
Pilot Study ◽  
Short Segment ◽  
Barrett’S Epithelium ◽  
Novel Approach ◽  
Barrett's Epithelium

A Novel Approach to Penile Augmentation Urethroplasty Using Buccal Mucosa and Amniotic Membrane: A Pilot Study in a Rabbit Model

Urology ◽  
2016 ◽  
Vol 87 ◽  
pp. 210-215 ◽  
Author(s):  
Mustafa Güneş ◽  
Muammer Altok ◽  
Alime Güneş ◽  
Mehmet Umul ◽  
Zafer Özyıldız ◽  
...  
Keyword(s):  
Pilot Study ◽  
Amniotic Membrane ◽  
Buccal Mucosa ◽  
Rabbit Model ◽  
Novel Approach

Impact of autogenous concentrated bone marrow aspirate on bone regeneration after sinus floor augmentation with a bovine bone substitute - a split-mouth pilot study

2013 ◽  
Vol 25 (10) ◽  
pp. 1175-1181 ◽  
Author(s):  
Angelika Wildburger ◽  
Michael Payer ◽  
Norbert Jakse ◽  
Dirk Strunk ◽  
Nathalie Etchard-Liechtenstein ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Pilot Study ◽  
Bone Regeneration ◽  
Bone Substitute ◽  
Bone Marrow Aspirate ◽  
Bovine Bone ◽  
Concentrated Bone Marrow ◽  
Sinus Floor Augmentation ◽  
Sinus Floor

scholarly journals A Novel Approach Towards Less Invasive Multi ‘Omics Gut Analyses: A Pilot Study

2021 ◽  
Author(s):  
Adam J. Berlinberg ◽  
Ana Brar ◽  
Andrew Stahly ◽  
Mark E. Gerich ◽  
Blair P. Fennimore ◽  
...  
Keyword(s):  
Pilot Study ◽  
Human Microbiome ◽  
Screening Colonoscopy ◽  
Intestinal Biopsy ◽  
Sample Collection ◽  
Less Invasive ◽  
Novel Approach ◽  
Functional Assessments ◽  
Invasive Method ◽  
Cytology Brush

Newer ‘omics approaches such as metatranscriptomics and metabolomics allow functional assessments of the interaction(s) between the gut microbiome and the human host. In order to generate meaningful data with these approaches, though, the method of sample collection is critical. Prior studies have relied upon expensive and invasive means towards sample acquisition such as intestinal biopsy, while other studies have relied upon easier methods of collection such as fecal samples that do not necessarily represent those microbes in contact with the host. In this pilot study, we attempt to characterize a novel, minimally invasive method towards sampling the human microbiome using mucosal cytology brush sampling compared to intestinal gut biopsy on 5 healthy participants undergoing routine screening colonoscopy. We compared metatranscriptomic analyses between the two collection methods, identifying increased taxonomic evenness and beta diversity in the cytology brush samples, and similar community transcriptional profiles between the two methods. Metabolomics assessment demonstrated striking differences between the two methods, implying a difference in bacterial-derived versus human absorbed metabolites. Put together, this study supports the use of a less invasive method of microbiome sampling with cytology brushes, but caution must be exercised when performing metabolomics assessment as this represents differential metabolite production but not absorption by the host.

A Novel Approach to Search for Identity by Descent in Small Samples of Patients and Controls from the Same Mendelian Breeding Unit: A Pilot Study on Myopia

2001 ◽  
Vol 52 (4) ◽  
pp. 183-190 ◽  
Author(s):  
Simon Heath ◽  
Renato Robledo ◽  
William Beggs ◽  
Gaetano Feola ◽  
Carlo Parodo ◽  
...  
Keyword(s):  
Pilot Study ◽  
Small Samples ◽  
Identity By Descent ◽  
Novel Approach
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