Double Centrifugation Versus Single Centrifugation of Bone Marrow Aspirate Concentrate in Sinus Floor Elevation: A Pilot Study

2016 ◽  
Vol 31 (1) ◽  
pp. 216-222 ◽  
Author(s):  
Thiago de Oliveira ◽  
Antonio Aloise ◽  
José Orosz ◽  
Rafael de Mello e Oliveira ◽  
Paulo de Carvalho ◽  
...  
2013 ◽  
Vol 25 (10) ◽  
pp. 1175-1181 ◽  
Author(s):  
Angelika Wildburger ◽  
Michael Payer ◽  
Norbert Jakse ◽  
Dirk Strunk ◽  
Nathalie Etchard-Liechtenstein ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Paulo José Pasquali ◽  
Marcelo Lucchesi Teixeira ◽  
Thiago Altro de Oliveira ◽  
Luis Guilherme Scavone de Macedo ◽  
Antonio Carlos Aloise ◽  
...  

Purpose. To investigate the regenerative results obtained with the association of bone marrow aspirate concentrate using the Bone Marrow Aspirate Concentrate (BMAC) method to a xenogeneic bone graft (Bio-Oss) in sinus floor elevation.Materials and Methods. Using a randomized controlled study design in eight consecutive patients (age of 55.4 ± 9.2 years), 16 sinus floor lift procedures were performed with Bio-Oss alone (control group, CG,n=8) or combined with bone marrow aspirate concentrate obtained via the BMAC method (test group, TG,n=8). Six months after the grafting procedures, bone biopsies were harvested during implant placement and were analyzed by histomorphometry.Results. Histomorphometric analysis revealed a significantly higher amount(p<0.05)of vital mineralized tissue in TG when compared to the CG (55.15 ± 20.91% and 27.30 ± 5.55%, resp.). For nonvital mineralized tissue, TG presented a statistically higher level of Bio-Oss resorption(p<0.05)when compared with the CG (6.32 ± 12.03% and 22.79 ± 9.60%, resp.). Both groups (TG and CG) showed no significantly different levels (p>0.05) of nonmineralized tissue (38.53 ± 13.08% and 49.90 ± 7.64%, resp.).Conclusion. The use of bone marrow concentrate obtained by BMAC method increased bone formation in sinus lift procedures.


2021 ◽  
pp. 2140004
Author(s):  
Kathryn A. Farina ◽  
Blake A. Kandah ◽  
Nan M. Sowers ◽  
Gregory A. Moore

Achilles tendon disorders, including tendinopathy and ruptures, are common among competitive runners. Relatively high complication rates, recurring injuries, and the need to return to sport have led to the use of regenerative medical treatment in tendon disorders in competitive athletes. Biologic therapies, including bone marrow aspirate concentrate (BMAC) injections, have been effective in restoring injured tissue in a limited number of cases. In this case, a collegiate cross country runner with Achilles tendon pain underwent years of failed, non-surgical conservative management. The patient’s MRI demonstrated moderate distal calcaneus tendinosis with high-grade partial thickness tearing of the anterior fibers of the Achilles tendon (50% tear). The patient underwent peritendinous injection of BMAC. Post-procedure MRI demonstrated minimal tendinosis of the distal and lateral margins of the Achilles tendon, and no evidence of Achilles tendon tear. The patient followed a progressive return to running program, ultimately training 40 miles per week with minimal Achilles tendon pain.


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