scholarly journals Pyomyositis in a Patient Undergoing Chemotherapy for Gastric Cancer: A Case Report and Literature Review

2021 ◽  
pp. 1220-1227
Author(s):  
Yoko Nakayama ◽  
Akira Sugiyama ◽  
Tetsu Yamamoto ◽  
Ryoji Hyakudomi ◽  
Noriyuki Hirahara ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Skeletal Muscles ◽  
Complete Recovery ◽  
Sudden Onset ◽  
Left Lower Extremity ◽  
Immunodeficiency Virus ◽  
Old Japanese ◽  
Weighted Magnetic Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
High Intensity Signal

Pyomyositis has recently been recognized as a primary infection of the large skeletal muscles, and it is often accompanied by single or multiple intramuscular abscess formation. Immunocompromised patients, including those with diabetes mellitus, human immunodeficiency virus infection, and cancer, as well as those undergoing chemotherapy, are at a greater risk of developing pyomyositis. A 78-year-old Japanese man with recurrent gastric cancer being treated with chemotherapy presented with sudden-onset pain in his left lower extremity while undergoing a second-line regimen with irinotecan. T2-weighted magnetic resonance imaging (MRI) showed an abnormally high-intensity signal in the left internal and external obturator muscles, a finding consistent with pyomyositis. Following intensive antibiotic treatment, the patient recovered completely and was able to resume chemotherapy with irinotecan. For a patient who developed pyomyositis during chemotherapy for gastric cancer, early diagnosis using MRI followed by administration of timely intensive antibiotic therapy resulted in complete recovery.

scholarly journals Thrombotic antiphospholipid syndrome in a child with Human Immunodeficiency Virus: A rare Case Report

2020 ◽  
Author(s):  
Rong-Jing Dong ◽  
Su-Yun Lei ◽  
Jun Li ◽  
Xin-Ping Yang ◽  
yuye li ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Pediatric Population ◽  
Autoimmune Disorder ◽  
Sudden Onset ◽  
Hiv Positive ◽  
High Dose ◽  
Hiv Viral Load ◽  
Left Lower Extremity ◽  
Immunodeficiency Virus ◽  
Rare Case Report

Abstract BACKGROUNDAntiphospholipid syndrome (APS) is a noninflammatory autoimmune disorder induced by antiphospholipid antibodies, which exceedingly rarely occurs in pediatric population and even more rarely reported in HIV positive children.CASE SUMMARYA 11 years old boy had a sudden onset left lower extremity swelling with pain and the symptoms gradually worsened. Initial one-month topical treatment was ineffective and the symptoms aggravated until suddenly spread to the root of his thigh, accompanied by left lower extremity dyskinesia. Both ultrasonography and vascular CT scan on left lower extremity revealed deep venous thrombosis. His serum aPLs antibodies were tested positive. He experienced a virology failure with substantial HIV viral load (VL) despite receiving regular antiretroviral therapy (ART). The symptoms recovered after aggressive antithrombotic and high-dose corticosteroids treatments.CONCLUSIONWhen pediatric individuals develop thrombotic disease, APS also needs to be ruled out. The autoantibodies levels should be routinely tested to look for recurrent thrombosis in children with HIV/AIDS.

scholarly journals Neuroendocrine carcinoma arising in a wound of the postoperative maxillary sinus

2012 ◽  
Vol 2 (1) ◽  
pp. 16
Author(s):  
Takeshi Kusunoki ◽  
Katsuhisa Ikeda
Keyword(s):  
Maxillary Sinus ◽  
Neuroendocrine Carcinoma ◽  
Past History ◽  
Japanese Woman ◽  
Old Japanese ◽  
Weighted Magnetic Resonance Imaging ◽  
Maxillary Cyst ◽  
Left Maxillary Sinus ◽  
Eye Movement Disorders ◽  
Cheek Swelling

We report a case of a neuroendocrine carcinoma arising in a wound of the postoperative maxillary sinus that was difficult to distinguish from a postoperative maxillary cyst. The patient was a 65-year-old Japanese woman who complained of left exophthalmos with cheek swelling and eye movement disorders. In past history, she had, 40 years previously undergone operation on the bilateral maxillary sinus by Caldwell-Luc’s method. In a preoperative computed tomography, a mass occupied the left maxillary sinus showing irregular densities with destruction of the posterior bone walls and invasion into the left orbital. Both TI and T2 weighted magnetic resonance imaging showed low intensities and unevenness in the mass. We performed a biopsy of the maxillary tumor according to Caldwell-Luc’s method. Histological examination diagnosed neuroendocrine carcinoma. Radiation therapy (total 66Gy) resulted in partial response for this tumor. However, sinonasal neuroendocrine carcinoma has been identified as highly aggressive, with a high probability of recurrence and metastasis.

scholarly journals Statistical Estimation of Accelerated Biological Brain Aging After Mild Traumatic Brain Injury in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 890-890
Author(s):  
Andrei Irimia ◽  
Jun Kim ◽  
Shania Wang ◽  
Hyung Jun Lee ◽  
Van Ngo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Brain Aging ◽  
Rate Of Change ◽  
Time Period ◽  
Weighted Magnetic Resonance Imaging ◽  
Neurological Conditions ◽  
Magnetic Resonance Imaging Mri ◽  
Brain Age

Abstract Estimating biological brain age (BA) has the potential of identifying individuals at relatively high risk for accelerated neurodegeneration. This study compares the brain’s chronological age (CA) to its BA and reveals the BA rate of change after mild traumatic brain injury (mTBI) in an aging cohort. Using T1-weighted magnetic resonance imaging (MRI) volumes and cortical thickness, volume, surface area, and Gaussian curvature obtained using FreeSurfer software; we formulated a multivariate linear regression to determine the rate of BA increase associated with mTBI. 95 TBI patients (age in years (y): μ = 41 y, σ = 17 y; range = 18 to 83) were compared to 462 healthy controls (HCs) (age: μ = 69 y, σ = 18 y; range = 25 to 95) over a 6-month time period following mTBI. Across the initial ~6 months following injury, patients’ BAs increased by ~3.0 ± 1.2 years due to their mTBIs alone, i.e., above and beyond typical brain aging. The superior temporal and parahippocampal gyri, two structures involved in memory formation and retrieval, exhibited the fastest rates of TBI-related BA. In both hemispheres, the volume of the hippocampus decreased (left: μ=0.28%, σ=4.40%; right: μ=0.12%, σ=4.84%). These findings illustrate BA estimation techniques’ potential to identify TBI patients with accelerated neurodegeneration, whose rate is strongly associated with the risk for dementia and other aging-related neurological conditions.

Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder

2016 ◽  
Vol 46 (9) ◽  
pp. 1971-1985 ◽  
Author(s):  
K. N. Jørgensen ◽  
S. Nerland ◽  
L. B. Norbom ◽  
N. T. Doan ◽  
R. Nesvåg ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
White Matter ◽  
Linear Models ◽  
Subcortical White Matter ◽  
Precentral Gyrus ◽  
Average Group ◽  
Medication Dose ◽  
Weighted Magnetic Resonance Imaging ◽  
The Difference ◽  
Magnetic Resonance Imaging Mri

BackgroundSchizophrenia and bipolar disorder share genetic risk factors and one possible illness mechanism is abnormal myelination. T1-weighted magnetic resonance imaging (MRI) tissue intensities are sensitive to myelin content. Therefore, the contrast between grey- and white-matter intensities may reflect myelination along the cortical surface.MethodMRI images were obtained from patients with schizophrenia (n = 214), bipolar disorder (n = 185), and healthy controls (n = 278) and processed in FreeSurfer. The grey/white-matter contrast was computed at each vertex as the difference between average grey-matter intensity (sampled 0–60% into the cortical ribbon) and average white-matter intensity (sampled 0–1.5 mm into subcortical white matter), normalized by their average. Group differences were tested using linear models covarying for age and sex.ResultsPatients with schizophrenia had increased contrast compared to controls bilaterally in the post- and precentral gyri, the transverse temporal gyri and posterior insulae, and in parieto-occipital regions. In bipolar disorder, increased contrast was primarily localized in the left precentral gyrus. There were no significant differences between schizophrenia and bipolar disorder. Findings of increased contrast remained after adjusting for cortical area, thickness, and gyrification. We found no association with antipsychotic medication dose.ConclusionsIncreased contrast was found in highly myelinated low-level sensory and motor regions in schizophrenia, and to a lesser extent in bipolar disorder. We propose that these findings indicate reduced intracortical myelin. In accordance with the corollary discharge hypothesis, this could cause disinhibition of sensory input, resulting in distorted perceptual processing leading to the characteristic positive symptoms of schizophrenia.

scholarly journals Use of Magnetic Resonance Imaging to Predict Outcome after Stroke: A Review of Experimental and Clinical Evidence

2010 ◽  
Vol 30 (4) ◽  
pp. 703-717 ◽  
Author(s):  
Tracy D Farr ◽  
Susanne Wegener
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Complete Recovery ◽  
Research Translation ◽  
Resonance Imaging ◽  
Preclinical Research ◽  
Stroke Research ◽  
Future Potential ◽  
Magnetic Resonance Imaging Mri ◽  
The Individual

Despite promising results in preclinical stroke research, translation of experimental data into clinical therapy has been difficult. One reason is the heterogeneity of the disease with outcomes ranging from complete recovery to continued decline. A successful treatment in one situation may be ineffective, or even harmful, in another. To overcome this, treatment must be tailored according to the individual based on identification of the risk of damage and estimation of potential recovery. Neuroimaging, particularly magnetic resonance imaging (MRI), could be the tool for a rapid comprehensive assessment in acute stroke with the potential to guide treatment decisions for a better clinical outcome. This review describes current MRI techniques used to characterize stroke in a preclinical research setting, as well as in the clinic. Furthermore, we will discuss current developments and the future potential of neuroimaging for stroke outcome prediction.

Emergency Magnetic Resonance Examination of Patients with Spinal Cord Symptoms

1988 ◽  
Vol 29 (1) ◽  
pp. 69-75 ◽  
Author(s):  
E.-M. Larsson ◽  
S. Holtås ◽  
S. Cronqvist
Keyword(s):  
Spinal Cord ◽  
Magnetic Resonance ◽  
Epidural Abscess ◽  
Imaging System ◽  
Epidural Haematoma ◽  
Sudden Onset ◽  
Surface Coils ◽  
Signal Characteristics ◽  
Traumatic Lesions ◽  
Magnetic Resonance Imaging Mri

Eighteen consecutive patients with spinal cord symptoms of sudden or relatively sudden onset were examined with magnetic resonance imaging (MRI). The examinations were performed on a 0.3 tesla permanent/resistive imaging system using solenoidal surface coils. MRI revealed epidural tumour in five patients, intramedullary tumour in one, epidural abscess in one, myelitis in two, spontaneous intraspinal epidural haematoma in two, disc herniation in two, traumatic lesions in four and no abnormality in one patient. MRI was found to be capable of non-invasively and painlessly detecting and exactly defining the extent of intraspinal and paraspinal lesions. In some cases the nature of the lesion could be inferred from specific signal characteristics, which is a unique property of MRI. The results strongly suggest that MRI is superior to myelography and other imaging methods and should be regarded as the examination of choice in the emergency examination of patients with spinal cord symptoms.

scholarly journals Non traumatic spinal epidural haematoma

2019 ◽  
Vol 18 (4) ◽  
pp. 255-258
Author(s):  
Naureen Abdul Khalid ◽  
◽  
Nainal Shah ◽  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Trauma Surgery ◽  
Epidural Haematoma ◽  
Rare Condition ◽  
Sudden Onset ◽  
Resonance Imaging ◽  
Spinal Epidural Haematoma ◽  
History Of ◽  
Magnetic Resonance Imaging Mri ◽  
Spinal Epidural

Spinal epidural haematoma is a rare condition, which may be due to trauma, surgery, epidural catheterisation or disorders of coagulation. We report a case of 60 year old lady who was on warfarin for Atrial fibrillation (AF) presented with history of non-traumatic sudden onset pain in both legs and difficulty in walking. Magnetic resonance imaging (MRI) spine demonstrated epidural haematoma which was treated conservatively. Another dilemma was anticoagulation for AF. We examine the options to manage such case.

scholarly journals MRI Virtual Biopsy of T2 Hyperintense Breast Lesions

2021 ◽  
Vol 11 ◽  
pp. 18
Author(s):  
Swati Sharma ◽  
Chidi Nwachukwu ◽  
Carissa Wieseler ◽  
Sherif Elsherif ◽  
Haley Letter ◽  
...  
Keyword(s):  
Breast Lesions ◽  
Resonance Imaging ◽  
Post Contrast ◽  
Comprehensive Review ◽  
Hyperintense Signal ◽  
Mri Features ◽  
Malignant Breast ◽  
Weighted Magnetic Resonance Imaging ◽  
Pre Treatment ◽  
Magnetic Resonance Imaging Mri

A wide variety of benign and malignant breast processes may generate hyperintense signal at T2-weighted magnetic resonance imaging (MRI). MRI has been traditionally used in the pre-treatment planning of breast cancer, in assessing treatment response and detecting recurrence. In this comprehensive review, we describe and illustrate the MRI features of a few common and uncommon T2 hyperintense breast lesions, with an emphasis on MRI features that help to characterize lesions based on morphological features, specific appearances on T1-and T2-weighted imaging, and enhancement characteristics on the dynamic post-contrast phase that are either diagnostic or aid in narrowing the differential diagnosis.

Sign in / Sign up

Export Citation Format

Share Document