scholarly journals Tineа Corporis with Trichophyton Rubrum Mimicking a Flare-Up of Psoriasis UnderTreatment with IL17-Inhibitor Ixekizumab

2021 ◽  
pp. 347-351
Author(s):  
Vladimir Emelianov ◽  
Laurence Feldmeyer ◽  
Nikhil Yawalkar ◽  
Kristine Heidemeyer
Keyword(s):  
Differential Diagnosis ◽  
Plaque Psoriasis ◽  
Clinical Picture ◽  
Side Effect ◽  
Trichophyton Rubrum ◽  
Tinea Corporis ◽  
Concomitant Treatment ◽  
Severe Plaque Psoriasis ◽  
Candida Infections ◽  
Dermatophyte Infection

Biologics, as IL17 inhibitors, are frequently prescribed for moderate to severe plaque psoriasis. Although mucocutaneous candida infections are a well-known side effect of IL-17 inhibitors, there is no data about dermatophyte infection under this therapy. Generalized tinea corporis can mimic the clinical picture of psoriasis, especially if concomitant treatment with topical corticosteroids is used. Therefore, physician should be aware of this differential diagnosis if they suspect a loss of efficacy of IL-17-inhibitors with a flare-up of psoriasis.

Evaluation of the PGAxBSA Composite Tool in Patients with Moderate-to-Severe Plaque Psoriasis

2017 ◽  
Vol 1 ◽  
pp. s14
Author(s):  
Kristina Callis Duffin ◽  
J Mark Jackson ◽  
Joana Goncalves ◽  
Eugenia Levi ◽  
Jerry Bagel
Keyword(s):  
Plaque Psoriasis ◽  
Severe Plaque Psoriasis ◽  
Composite Tool

Abstract Not Available Disclosure: Study supported by Celgene.

Comparison of Ixekizumab and Ustekinumab Efficacy in the Treatment of Nail Lesions of Patients With Moderate-to-Severe Plaque Psoriasis: 52-Week Data From the IXORA-S Trial

2018 ◽  
Vol 2 ◽  
pp. S117
Author(s):  
Norman Wasel ◽  
Yves Dutronc ◽  
Birgit Schinzel ◽  
Jean-Philippe Lacour
Keyword(s):  
Plaque Psoriasis ◽  
Severe Plaque Psoriasis

Abstract not available. Disclosures: Study sponsored by Eli Lilly & Company. Copyright 2018 SKIN

Pharmacoeconomic analysis of using genetically engineered biologic drugs for treating adult patients with moderate to severe plaque psoriasis in the Russian Federation

2020 ◽  
pp. 57-65
Author(s):  
Maksim Frolov ◽  
Vladimir Rogov ◽  
Alla Salasyuk
Keyword(s):  
Plaque Psoriasis ◽  
Impact Analysis ◽  
Pharmacoeconomic Analysis ◽  
Certolizumab Pegol ◽  
Genetically Engineered ◽  
Adult Patients ◽  
Comparable Efficacy ◽  
Biologic Drugs ◽  
Severe Plaque Psoriasis ◽  
Cost Minimisation Analysis

The aim of the study was to assess clinical and economic effectiveness of netakimab compared to other genetically engineered biologic drugs (infliximab, adalimumab, etanercept, ustekinumab, secukinumab, ixekizumab, certolizumab pegol) for the treatment of adult patients with moderate to severe plaque psoriasis. We have conducted cost-benefit analysis, cost-minimisation analysis, and budget impact analysis. We have considered only direct medical costs. The results of the study show that netakimab has higher or comparable efficacy and significantly lower costs compared to other biologic drugs, that makes it the most preferable treatment option for patients with moderate to severe plaque psoriasis. Use of netakimab in clinical practice will significantly reduce budget expenditures and increase patient access to biologic therapy.

DIAGNOSTICS AND TREATMENT OF POISONING WITH THALLIUM

2018 ◽  
pp. 9-15 ◽  
Author(s):  
L. B. Zavaliy ◽  
A. Yu. Simonova ◽  
M. M. Potskhveriya ◽  
Yu. N. Ostapenko ◽  
M. G. Gadzhieva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Clinical Picture ◽  
Clinical Guidelines ◽  
The Body ◽  
Biological Media ◽  
Pathophysiological Mechanisms ◽  
Thallium Poisoning ◽  
The World

Cases of thallium poisonings are regularly reported in media. In the present work, the world experience in diagnostics and treatment of victims with thallium poisoning has been compiled and summarized, search for clinical guidelines for the diagnostics, treatment and rehabilitation of patients has been carried out. The toxicokinetics and toxicodynamics, as well as pathophysiological mechanisms of thallium influence on the body are described in detail. Toxic and lethal concentrations of poison in biological media, as well as its tropicity to various tissues and body systems were determined. The clinical picture depending on the timing of poisoning and the dose of poison is described in detail. Difficulties of the differential diagnosis are defined. The most interesting cases of criminal and household poisonings with various terms of establishment of the diagnosis, doses of poisoning and outcomes are presented.

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