scholarly journals Syringe with Nasal Applicator versus Syringe Alone for Nasal Irrigation in Acute Rhinosinusitis: A Matched-Pair Randomized Controlled Trial

2021 ◽  
pp. 25-29
Author(s):  
Patorn Piromchai ◽  
Chayakorn Phannikul ◽  
Sanguansak Thanaviratananich
Keyword(s):  
Adverse Effects ◽  
Respiratory Tract ◽  
The Other ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
Nasal Irrigation ◽  
Acute Rhinosinusitis ◽  
The Mean ◽  
Upper Respiratory ◽  
Acute Rhinitis

<b><i>Background/Aims:</i></b> Nasal saline irrigation is a common procedure to relieve nasal symptoms in upper respiratory tract diseases. There is no consensus on the recommended nasal saline delivery devices. The objectives of this study were to evaluate efficacy, satisfaction, adherence, and adverse effects in patients with acute upper respiratory tract diseases using a syringe with a nasal applicator for nasal irrigation. <b><i>Methods:</i></b> Patients with acute nasopharyngitis, acute rhinitis, or acute rhinosinusitis were randomly allocated to use either (1) a syringe with a nasal applicator or (2) a syringe alone to irrigate one nostril. After the patients had completed irrigation with the allocated device in one nostril, they were instructed to perform nasal irrigation using the other device in the other nostril. All patients were instructed to use a syringe with a nasal applicator at home. The efficacy, satisfaction scores, adherence, and adverse effects were recorded. <b><i>Results:</i></b> Sixty-four patients were enrolled. The mean age of the patients was 33.95 years (18–59 years). The mean duration of symptoms was 4.80 days. None of the enrolled patients regularly performed nasal irrigation. Forty-two had acute nasopharyngitis, 10 had acute rhinitis, and 12 had acute rhinosinusitis. At baseline, the mean overall efficacy score for the syringe with a nasal applicator was 8.17 ± 1.43, and that for the syringe alone was 5.95 ± 2.02 (MD 2.23, <i>p</i> &#x3c; 0.001, 95% CI 1.75–2.70). At 1 week, the syringe with the nasal applicator had significantly higher scores in 3 of 4 domains, including symptom relief, ease of use, and patients’ willingness to recommend the device to others, compared to baseline (<i>p</i> &#x3c; 0.05). None of the enrolled patients had epistaxis, retained/dislodged the applicator during irrigation, or experienced an allergic reaction to the applicator after 1 week of nasal irrigation. <b><i>Conclusion:</i></b> Use of a syringe with an applicator for nasal irrigation yielded high scores in overall efficacy.

scholarly journals Animal Coronaviruses and SARS-COV-2 in Animals, What Do We Actually Know?

Life ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 123
Author(s):  
Paolo Bonilauri ◽  
Gianluca Rugna
Keyword(s):  
Veterinary Medicine ◽  
Respiratory Tract ◽  
Common Cold ◽  
Domestic Animals ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
The Common ◽  
Upper Respiratory

Coronaviruses (CoVs) are a well-known group of viruses in veterinary medicine. We currently know four genera of Coronavirus, alfa, beta, gamma, and delta. Wild, farmed, and pet animals are infected with CoVs belonging to all four genera. Seven human respiratory coronaviruses have still been identified, four of which cause upper-respiratory-tract diseases, specifically, the common cold, and the last three that have emerged cause severe acute respiratory syndromes, SARS-CoV-1, MERS-CoV, and SARS-CoV-2. In this review we briefly describe animal coronaviruses and what we actually know about SARS-CoV-2 infection in farm and domestic animals.

scholarly journals Preventive and therapeutic role of nasal irrigation in management of acute respiratory disease during COVID-19 pandemic and beyond

2021 ◽  
pp. 58-64
Author(s):  
V. M. Svistushkin ◽  
Zh. T. Mokoyan
Keyword(s):  
Respiratory Tract ◽  
Nasal Cavity ◽  
Distribution Area ◽  
Upper Respiratory Tract ◽  
Saline Irrigation ◽  
Nasal Irrigation ◽  
Wide Range ◽  
Upper Respiratory ◽  
Nasal Saline Irrigation ◽  
Tract Infections

It has long been known, that nasal saline irrigation is a safe and effective method, which is routinely prescribed by otorhinolaryngologists to prevent and to treat a wide range of pathologies. There are a lot of publications on different irrigation techniques and methods. This literature review discusses the key parameters of nasal irrigation, including tonicity, pH, and the additional components, and explains how they affect the effectiveness of the procedure. The vast majority of available publications did not found any possible changes in the effectiveness of solutions with different pH close to neutral meaning. Whereas, the volume of the irrigated solution, increases the efficiency of the irrigation in direct proportion. Thus, the largest distribution area of the solute is noted when washing with a large volume of liquid. Nasal saline irrigation is an effective treatment option for patients with several acute and chronic diseases and for postoperative care after rhinosurgery. Moreover, nasal irrigation might be used as an effective non-specific method for prevention of acute upper respiratory tract infections. Irrigation of the nasal cavity reduces the mucus viscosity and promotes its faster elimination, along with pathogens fixed in it. Additionally, irrigation with isotonic saline solutions increases the hydration of the underlying water base, which enhances the frequency of ciliary beat and reduces the concentration of local inflammatory mediators. COVID-19 pandemic situation due to lack of any specific antiviral drugs dictates the necessity of an effective non-specific preventive option, which could be introduced worldwide. The so-called full volume lavage of the nasal cavity allows for better cleaning of the nasal cavity and effective moisturizing of the mucous membrane. It is the timely cleansing and moisturizing that are most important for maintaining the normal activity of the local protective mechanisms of the upper respiratory tract.

Toxic gases and aerosols

2010 ◽  
pp. 3456-3458
Author(s):  
D.J. Hendrick
Keyword(s):  
Adverse Effects ◽  
Respiratory Tract ◽  
Acute Exposure ◽  
Upper Respiratory Tract ◽  
Solubility In Water ◽  
Toxic Gases ◽  
Lower Solubility ◽  
Main Effect ◽  
Upper Respiratory

Acute exposure—the effects of noxious gases or aerosols on the airways and lungs are determined by (1) their solubility in water, with those that are highly soluble having their main effect on the lining of the upper respiratory tract and those with lower solubility mainly affecting the lungs, and (2) the dose of exposure, with overwhelming exposures having adverse effects throughout the respiratory tract....

scholarly journals The Haemophilic Bacteria of the Upper Respiratory Tract, the Appearance of Virulent forms in Relation to Upper Respiratory Infections

1934 ◽  
Vol 34 (2) ◽  
pp. 195-202 ◽  
Author(s):  
L. Hoyle
Keyword(s):  
Respiratory Tract ◽  
Respiratory Infections ◽  
Bacterial Flora ◽  
The Other ◽  
Upper Respiratory Tract ◽  
Upper Respiratory Infections ◽  
Acute Infections ◽  
Other Hand ◽  
Upper Respiratory ◽  
Normal Health

In previous studies of the bacterial flora of the upper respiratory tract and its variations during attacks of acute coryza (Hoyle, 1932), it was found that there was in many cases a striking relationship between the appearance of certain organisms with definite pathogenic properties towards the lower animals, in the upper respiratory tract, and the occurrence of acute infections. This relationship was especially marked in the case of the influenza bacillus, and it was suggested that this organism played a prominent part in the aetiology of upper respiratory infections. The significance of the influenza bacillus in acute coryza has been noted by various workers (Noble, Fisher and Brainard, 1928; Burky and Smillie, 1929; Webster and Clow, 1932; Kneeland and Dawes, 1932), but on the other hand various observers have found the incidence of influenza bacilli in the respiratory tract to be the same in normal health and in acute coryza, and Fleming (1929) and Fleming and Maclean (1930) have devised a technique by means of which they claim to have isolated influenza bacilli in 100 per cent, of normal throats. One possible explanation of these conflicting results may be found in the absence of any very exact criterion of what constitutes a typical influenza bacillus.

scholarly journals Czy smog ma wpływ na częstość występowania zaostrzeń przewlekłego zapalenia krtani? Analiza na przykładzie mieszkańców województwa małopolskiego

2017 ◽  
Vol 71 (3) ◽  
pp. 10-19 ◽  
Author(s):  
Remigiusz Ziarno ◽  
Anna Suska ◽  
Wojciech Kulinowski ◽  
Aleksandra Grudzień-Ziarno ◽  
Magdalena Kostrzon ◽  
...  
Keyword(s):  
Air Pollution ◽  
Respiratory Tract ◽  
Vocal Folds ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
Place Of Residence ◽  
Chronic Laryngitis ◽  
Upper Respiratory

Introduction: Due to dynamic industrialisation smog became a frequent phenomenon in most developing cities. According to the last WHO report from Global Urban Ambient Air Pollution Database, Krakow has been classified in the 11th place among the most polluted cities in Europe. It seems to be an urgent issue because of the influence of air pollution on the condition of upper respiratory tract. Materials & Methods: In December 2015 there were 141 patients aged 17-91 years with upper respiratory tract diseases admitted to the phoniatric outpatient clinic in the University Hospital in Cracow. They suffered from cough, hoarseness and periodic aphonia. On the basis of the results of videolaryngostroboscopy 60 patients with exacerbation of the chronic laryngitis were selected into two numerically equal groups: from Cracow and from other places at least 60 km away. The groups were equal to each other also in three categories: sex, age and voice usage. The patients were referred to the Pedagogical University in Cracow for laryngography to evaluate the movement of the vocal folds and to trace a voice profile. Finally, there were two possible types of treatment – conventional pharmacotherapy or subterraneotherapy in the underground Health Resort in the "Wieliczka" Salt Mine. Results: Pearson correlation coefficient between the distance from the place of residence to Cracow and the scale of exacerbation of inflammation of upper respiratory tract presenting as vocal fold dysfunction was observed (r= 0,617; p<0,05). Conclusion: The place of residence (in or out of the industrial area) and exacerbations of chronic laryngitis are highly correlated. Air pollution seems to be the main factor influencing on the condition of upper respiratory tract. In our local conditions of Lesser Poland Voivodeship subterraneotherapy may be an interesting, non-invasive method preventing from exacerbations of upper respiratory tract diseases.

Treatment of the upper respiratory tract diseases in pregnant women

2018 ◽  
Vol 16 (5) ◽  
pp. 81-84
Author(s):  
M. A. Ryabova ◽  
◽  
O. V. Lavrova ◽  
N. A. Shumilova ◽  
L. V. Georgieva ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Pregnant Women ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
Upper Respiratory
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