scholarly journals Influence of Medical Compression Stockings on Skin Hydration in Mainly Health Care Givers with Occupational Leg Symptoms and Edema

2021 ◽  
Vol 34 (2) ◽  
pp. 57-73
Author(s):  
Marina Mayer-Yousif ◽  
Wolfgang Konschake ◽  
Hermann Haase ◽  
Michael Jünger ◽  
Helene Riebe
Keyword(s):  
Skin Barrier ◽  
Compression Therapy ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Skin Barrier Function ◽  
Interface Pressure ◽  
Compression Stockings ◽  
Care Givers ◽  
Leg Edema ◽  
Medical Compression Stockings

Background and Objective: Although compression therapy is a very effective therapy in reducing stasis-induced complaints, the wearing comfort is not always as requested. Most frequent problems are dryness of the skin and itching. This randomized, cross-over trial investigated 33 healthy participants and compared 2 different medical compression stockings: conventional stockings (type A = MCS) versus compression stockings with integrated care emulsion (type B = MCS-SkC). Methods: Participants were divided into 2 cohorts. Both compression types were worn one after the other, 1 week each. The cohorts were named according to the sequence of the wearing periods (cohort AB/BA). Primary outcome: skin hydration. Secondary outcomes: transepidermal water loss (TEWL), skin roughness, leg volume, interface pressure, and questionnaires about stasis-induced complaints and wearing comfort. Results: Skin hydration: significant reduction after wearing MCS in both cohorts (p < 0.001); preservation of skin moisture after wearing MCS-SkC (p = 0.546 and p = 0.1631). TEWL: significant increase after wearing MCS (p = 0.007 and p = 0.0031); significant reduction by wearing MCS-SkC (p = 0.006 and p = 0.0005). Skin roughness: significant increase after wearing MCS (p = 0.0015 and p = 0.010), and nonsignificant decrease of skin roughness after wearing MCS-SkC (p = 0.933 and p = 0.4570). Leg volume: significantly reduced with both stockings (p = 0.004 and p = 0.0047). Regarding stasis-induced complaints, both stockings achieved good results. Conclusions: Both compression stockings are appropriate to reduce leg edema and minimize leg symptoms. MCS-SkC helps to obtain the natural skin barrier function in preserving the epidermal water content and reducing the TEWL.

scholarly journals Medical compression stockings on the skin moisture in patients with chronic venous disease

VASA ◽  
2019 ◽  
Vol 48 (6) ◽  
pp. 502-508 ◽  
Author(s):  
Thea Westphal ◽  
Wolfgang Konschake ◽  
Hermann Haase ◽  
Marcus Vollmer ◽  
Michael Jünger ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Skin Care ◽  
Skin Hydration ◽  
Interface Pressure ◽  
Compression Stockings ◽  
Wear Comfort ◽  
Male Patients ◽  
Medical Compression Stockings ◽  
Skin Moisture

Summary: Background: Because of side effects like skin dryness and consecutive symptoms like itching the therapy of chronic venous insufficiency (CVI) with medical compression stockings (MCS) can lead to a diminished wear comfort and restricted compliance. Compression stockings with integrated skin care may have a positive influence on the skin hydration and moreover a positive effect on patients compliance. Patients and methods: In this monocentric, randomized prospective, controlled trial a below knee conventional MCS was compared to a medical compression stocking with integrated skin care (MCS-SC), interface pressure range 23–32 mmHg. Participants: 50 patients with CVI. Primary outcome: skin hydration. Secondary outcomes: transepidermal water loss, skin roughness, leg volume, interface pressure and questionnaires about quality of life and wear comfort. Results: In patients wearing MCS the skin moisture decreased (p = 0.021) and the skin roughness increased significantly (p = 0.001), whereas in patients wearing the MCS-SC skin moisture and skin roughness changed only slightly (n.s.). These protective effects of MCS-SC compared to MCS were most common in patients with CVI at stage 3 (p = 0.046), in male patients (p = 0.013) and patients with initial dry skin (p = 0.034). Both MCS reduced lower leg volume, MCS by 80 ml (p < 0.001) and MCS-SC by 60 ml (p < 0.001), both MCS improved quality of life: leg complaints (p = 0.0003); functional status (p = 0.010), well-being and life satisfaction (p = 0.030). Wear comfort: In terms of tightness, constriction in bond area and strenuous donning the MCS-SC was assessed significantly more comfortable than MCS (p < 0.001). Conclusions: MCS-SC revealed to be superior to MCS with regard to skin moisture, particularly in patients with low skin humidity, in male patients and in patients with C3, varicose veins accompanied by edema.

scholarly journals Moisturizing effect of a cosmetic formulation containing pequi oil (Caryocar brasiliense) from the Brazilian cerrado biome

2014 ◽  
Vol 50 (1) ◽  
pp. 131-136 ◽  
Author(s):  
Wanessa Costa Silva Faria ◽  
Gabriel Azevedo de Brito Damasceno ◽  
Márcio Ferrari
Keyword(s):  
Stratum Corneum ◽  
Water Content ◽  
Skin Barrier ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Skin Barrier Function ◽  
Brazilian Cerrado ◽  
Single Application ◽  
Caryocar Brasiliense ◽  
Stratum Corneum Water Content

Caryocar brasiliense, popularly known in Brazil as “pequi”, is a species widely distributed in the Brazilian Cerrado. The seeds are surrounded by a woody endocarp coated with a yellow fleshy mesocarp rich in oil and vitamin A, whose oil has a useful role in the treatment of skin aging and protection of human skin against UV-induced damage and skin hydration. The aim of this study was to evaluate the effect of cosmetic formulations containing pequi oil (Caryocar brasiliense) on skin hydration, after a single application. Hydration effect assessment was performed by applying the formulations under study (Control – no formulation, vehicle, and vehicle + pequi oil) onto forearm skin of 30 human volunteers. Skin capacitance and Transepidermal Water Loss (TEWL) measurements were analyzed before, and at 1, 2 and 3 hours after, a single application. Evaluation results of a single application of the vehicle containing pequi oil showed an increase in stratum corneum water content, indicating a skin moisturizing effect. Results of the evaluation of immediate effects of TEWL demonstrated that the vehicle containing pequi oil significantly increased skin moisture during the 3 h evaluation period. The formulations containing pequi oil showed clinical efficacy, increasing stratum corneum water content and enhancing skin barrier function.

scholarly journals Effect of Topically Applied Wikstroemia dolichantha Diels on the Development of Atopic Dermatitis-Like Skin Symptoms in Mice

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 914 ◽  
Author(s):  
Jonghwan Jegal ◽  
No-June Park ◽  
Tae-Young Kim ◽  
Sangho Choi ◽  
Sang Woo Lee ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Barrier Function ◽  
Immunoglobulin E ◽  
Skin Barrier ◽  
Skin Lesions ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Interleukin 4 ◽  
Skin Barrier Function ◽  
Skin Symptoms

Plants of the genus Wikstroemia are traditionally used to treat inflammatory diseases like bronchitis and rheumatoid arthritis. In the present study, the anti-atopic effects of an EtOH extract of Wikstroemia dolichantha (WDE) on oxazolone- and DNCB (2,4-dinitrochlorobenzene)-induced dermatitis in mice were investigated. Both ears of BALB/c mice were exposed to oxazolone, and dorsal skins of SKH-1 hairless mice were sensitized with DNCB to induce acute eczematous atopic skin lesions. 1% WDE was applied daily to oxazolone- and DNCB-induced AD mice for two or three weeks, respectively. Total IL-4 and IgE concentrations in serum, transepidermal water loss (TEWL) and skin hydration were assessed. High-performance liquid chromatography/mass spectrometry (HPLC/MS) was used to determine the composition of WDE. Dermal application of 1% WDE grossly and histopathologically improved oxazolone- and DNCB-induced AD skin symptoms. Epidermal thickness and mast cell infiltration were significantly lower in animals treated with WDE than in vehicle controls. Furthermore, in addition to reducing DNCB-induced increases in serum IL-4 (interleukin 4) and IgE (immunoglobulin E) levels, WDE also decreased TEWL and increased skin hydration (indicative of improved skin barrier function). The four flavonoids taxifolin, aromadendrin, padmatin and chamaejasmine were tentatively identified in WDE by HPLC-DAD/QTOF-MS. The above results show WDE protected against oxazolone- and DNCB-induced AD in mice by down-regulating the TH2-associated cytokine IL-4 and improving skin barrier function and suggest WDE might be useful for the management of atopic dermatitis.

scholarly journals Microbiome Profile in Adult Balanoposthitis Patients: Relationship with Redundant Prepuce, Skin Physical Barrier Status and Inflammation

2020 ◽  
Author(s):  
Meng Li ◽  
Jian-Xun Mao ◽  
Hang-Hang Jiang ◽  
Chun-Ming Huang ◽  
Xinghua Gao ◽  
...  
Keyword(s):  
Barrier Function ◽  
Skin Barrier ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Skin Barrier Function ◽  
Physical Barrier ◽  
Staphylococcus Warneri ◽  
Prevotella Bivia ◽  
Microbiome Profile ◽  
Associated Species

Abstract Background: Balanoposthitis is a common inflammatory condition of male genitalia, the microbiota spectrum have not been determined thus far. To profile the microbiome in patients with balanoposthitis (BP), and healthy controls (HC), and investigate its correlation with redundant prepuce, severity of inflammation, and disrupted skin barrier function, including skin pH, Transepidermal Water Loss (TEWL), and skin hydration.Results: In general, the microbiota between BP and HC were similar. The microbiota composition was different between BP and HC with redundant prepuce. Staphylococcus warneri and Prevotella bivia are two most abundant BP-associated Species, and positively correlated with disease severity. The physio-barrier function is markedly impaired in BP, shown by decreased skin hydration, while increased TEWL and pH.Conclusions: Staphylococcus warneri and Prevotella bivia showed a strong correlation with balanoposthitis and may be pathogenic for the condition.

scholarly journals GAMBARAN KADAR HIDRASI KULIT DAN KEJADIAN DERMATITIS KONTAK IRITAN PADA PETUGAS KEBERSIHAN DI UNIVERSITAS TARUMANAGARA

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Indi Chairunnisa ◽  
Linda Julianti Wijayadi ◽  
Sari Mariyati Dewi Nataprawira
Keyword(s):  
Contact Dermatitis ◽  
Water Loss ◽  
Skin Barrier ◽  
Skin Inflammation ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Skin Barrier Function ◽  
Irritant Contact Dermatitis ◽  
Dry Skin ◽  
Cross Sectional

Irritant contact dermatitis (DKI) is a non-immunologic skin inflammation reaction caused by contact with irritants. A janitor is a worker who does a lot of wet work that will repeatedly contact with irritants such as acids, bases, detergents, soap, water, solvents, etc., so that there will be damage to the skin barrier function that starts with loss of the lipid layer and Natural Moisturizing Factor (NMF) so it will reduce skin hydration levels and increase TransEpidermal Water Loss (TEWL). This makes the skin condition becomes dry and the skin defense decreases so that it is easier for DKI. The purpose of this study was to determine the description of skin hydration levels and the incidence of irritant contact dermatitis in janitors at Tarumanagara University. This research is descriptive with a cross-sectional design. A total of 60 people from the janitor became the subject of research. The level of skin hydration is measured by a chronometer. The incidence of DKI in the cleaning staff at Tarumanagara University was 10%, the level of skin hydration in the janitor at Tarumanagara University found hydration levels of dry skin on the right palm (76.7%), left palm (76.7%), back of the hand right (56.7%), and back of the left hand (56.7%). In subjects who experience DKI, levels of hydration of very dry skin on the palm (left-right) and hydration of dry skin on the back of the hand (left-right), and the factors that influence the occurrence of DKI are: gender (female), frequency of washing hands with soap per day, frequency and duration of contact with toilet and floor cleaning products per day and the use of personal protective equipment (PPE), and so it is recommended that cleaners always use PPE when working to prevent DKI and use moisturizers on dry skinABSTRAK:Dermatisis kontak iritan (DKI) adalah suatu reaksi peradangan kulit non-imunologik yang disebabkan oleh kontak dengan bahan iritan. Petugas kebersihan merupakan pekerja yang banyak melakukan pekerjaan basah yang  akan kontak berulang dengan bahan iritan seperti asam, basa, detergen, sabun, air, pelarut, dll, sehingga akan terjadi kerusakan fungsi sawar kulit yang dimulai dengan kehilangan lapisan lipid dan Natural Moisturizing Factor (NMF) sehingga akan menurunkan  kadar hidrasi kulit dan meningkatkan TransEpidermal Water Loss  (TEWL). Hal tersebut membuat kondisi kulit menjadi kering dan pertahanan kulit menurun sehingga lebih mudah terjadi DKI. Tujuan penelitian ini untuk mengetahui gambaran kadar hidrasi kulit dan kejadian dermatitis kontak iritan pada petugas kebersihan di Universitas Tarumanagara. Penelitian ini bersifat deskriptif dengan desain cross sectional. Sejumlah 60 orang dari petugas kebersihan menjadi subjek penelitian. Kadar hidrasi kulit diukur dengan alat korneometer. Angka kejadian DKI pada petugas kebesihan di Universitas Tarumanagara sebesar 10 %, Kadar hidrasi kulit pada petugas kebersihan di Universitas Tarumanagara didapatkan kadar hidrasi kulit  kering pada telapak tangan kanan (76,7%), telapak tangan kiri (76,7%), punggung tangan kanan (56,7%), dan punggung tangan kiri (56,7%). Pada subjek yang mengalami DKI didapatkan kadar hidrasi kulit sangat kering pada telapak tangan(kiri-kanan) dan hidrasi kulit kering  pada punggung tangan (kiri-kanan), dan faktor-faktor yang mempengaruhi kejadian DKI adalah: jenis kelamin (perempuan), frekuensi cuci tangan dengan sabun per hari, frekuensi dan lama kontak dengan produk pembersih toilet maupun lantai per hari dan penggunaan alat pelindung diri (APD), dan sehingga disarankan agar petugas kebersihan selalu memakai APD dengan lengkap saat bekerja untuk mencegah DKI dan menggunakan pelembab pada kulit yang kering

scholarly journals Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function and Cosmetic Performance upon Single and Repeated Usage in Subjects with Dry Skin

Cosmetics ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 44
Author(s):  
Ana Barrionuevo-Gonzalez ◽  
Sonja Trapp ◽  
Raffaella de Salvo ◽  
Rozalia Olsavszky ◽  
Elena Alina Nanu ◽  
...  
Keyword(s):  
Barrier Function ◽  
Skin Barrier ◽  
Transepidermal Water Loss ◽  
The Body ◽  
Skin Hydration ◽  
Skin Barrier Function ◽  
Lauryl Sulfate ◽  
Dry Skin ◽  
Study Results ◽  
Forearm Skin

Two novel body/face wash gels enriched with emollient ingredients (including dexpanthenol) were developed for the daily care of dry skin. Two similarly designed 2-week studies (N = 42 each) were conducted to assess the biophysical and cosmetic performance of each of the new wash gels in healthy adults with dry skin. Instrumental measurements quantified the effects of the wash gels on stratum corneum (SC) hydration and transepidermal water loss (TEWL) (with and without a previous sodium lauryl sulfate (SLS) challenge) after single and repeated usage. Following single and repeated applications of the face wash gel to facial skin, as well as to dry SLS-undamaged and SLS-damaged skin of the forearm, skin hydration significantly increased. Similarly, after single and repeated usage of the body wash gel to dry SLS-undamaged and SLS-damaged skin of the forearm, skin moisturization increased significantly from baseline; comparisons with control areas provided inconsistent results for SLS-undamaged skin. No effects on TEWL were observed for either product. Both wash gels were well tolerated and the cosmetic performances were appreciated by the subjects. The study results suggest that daily use of the new wash gels was associated with significant skin-moisturizing effects without adversely affecting skin barrier function and repair.

NATURAL COSMETICS IN THE CARE OF YOUNG CHILDREN

2020 ◽  
Vol 99 (6) ◽  
pp. 155-162
Author(s):  
O.B. Tamrazova ◽  
◽  
S.P. Seleznev ◽  
A.V. Tamrazova ◽  
◽  
...  
Keyword(s):  
Skin Barrier ◽  
Structural Features ◽  
Transepidermal Water Loss ◽  
General Information ◽  
Skin Barrier Function ◽  
Skin Physiology ◽  
Main Emphasis ◽  
Antimicrobial Protection ◽  
Irritant Dermatitis ◽  
Adaptive Shifts

The article provides general information about the skin physiology of newborns and infants. Structural features of the skin and main adaptive shifts in newborns, are described. Тhe child has an increase in the skin barrier function of the skin, which prevents transepidermal water loss; active synthesis of natural moisturizing factor (NMF) components that control skin hydration; shift of pH to acidic environment; normalization of thermoregulatory functions; enhancement of the photoprotective function; immune restructuring for antimicrobial protection; formation of a normal microbiome. The article describes the consequences of improper skin care of a newborn, using the example of diaper dermatitis, irritant dermatitis, prickly heat and vesiculopustulosis. The importance of using specialized children's cosmetics in caring for an infant is assessed. The basic recommendations for the choice of these products are presented, where the main emphasis is on the choice of products consisting of natural ingredients. Giving preference to natural cosmetics, everyone should carefully study the composition of these products and trust the manufacturers who can guarantee safety of care products for the youngest children.

scholarly journals Skin Barrier Function in Psoriasis and Atopic Dermatitis: Transepidermal Water Loss and Temperature as Useful Tools to Assess Disease Severity

2021 ◽  
Vol 10 (2) ◽  
pp. 359 ◽  
Author(s):  
Trinidad Montero-Vilchez ◽  
María-Victoria Segura-Fernández-Nogueras ◽  
Isabel Pérez-Rodríguez ◽  
Miguel Soler-Gongora ◽  
Antonio Martinez-Lopez ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Water Loss ◽  
Barrier Function ◽  
Skin Barrier ◽  
Transepidermal Water Loss ◽  
Diagnostic Tools ◽  
Psoriatic Skin ◽  
Skin Barrier Function ◽  
Healthy Controls

Multiple diagnostic tools are used to evaluate psoriasis and atopic dermatitis (AD) severity, but most of them are based on subjective components. Transepidermal water loss (TEWL) and temperature are skin barrier function parameters that can be objectively measured and could help clinicians to evaluate disease severity accurately. Thus, the aims of this study are: (1) to compare skin barrier function between healthy skin, psoriatic skin and AD skin; and (2) to assess if skin barrier function parameters could predict disease severity. A cross-sectional study was designed, and epidermal barrier function parameters were measured. The study included 314 participants: 157 healthy individuals, 92 psoriatic patients, and 65 atopic dermatitis patients. TEWL was significantly higher, while stratum corneum hydration (SCH) (8.71 vs. 38.43 vs. 44.39 Arbitrary Units (AU)) was lower at psoriatic plaques than at uninvolved psoriatic skin and healthy controls. Patients with both TEWL > 13.85 g·m−2h−1 and temperature > 30.85 °C presented a moderate/severe psoriasis (psoriasis area severity index (PASI) ≥ 7), with a specificity of 76.3%. TEWL (28.68 vs. 13.15 vs. 11.60 g·m−2 h−1) and temperature were significantly higher, while SCH (25.20 vs. 40.95 vs. 50.73 AU) was lower at AD eczematous lesions than uninvolved AD skin and healthy controls. Patients with a temperature > 31.75 °C presented a moderate/severe AD (SCORing Atopic Dermatitis (SCORAD) ≥ 37) with a sensitivity of 81.8%. In conclusion, temperature and TEWL values may help clinicians to determine disease severity and select patients who need intensive treatment.

scholarly journals Treatment of atopic dermatitis using non-thermal atmospheric plasma in an animal model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ik Jun Moon ◽  
Mi Ra Yun ◽  
Hae Kyeong Yoon ◽  
Keon Hee Lee ◽  
Sun Young Choi ◽  
...  
Keyword(s):  
Animal Model ◽  
Atopic Dermatitis ◽  
Skin Barrier ◽  
Treated Group ◽  
Transepidermal Water Loss ◽  
Atmospheric Plasma ◽  
Therapeutic Modality ◽  
Skin Barrier Function ◽  
Control Group ◽  
Epidermal Thickness

AbstractCold atmospheric plasma (CAP) has been incorporated into various fields, including promotion of cutaneous wound healing. Atopic dermatitis (AD) is a chronic cutaneous condition characterized by inflammation-induced skin wounds and impaired skin barrier function. To investigate whether CAP may improve AD using an animal model. Dermatophagoides farinae extracts (DFE)-induced murine models of AD were used in this study. The plasma-treated group received a total of 6 CAP treatments during 2 weeks, while the control group did not receive any treatment. Differences in dermatitis severity, transepidermal water loss (TEWL), serum level of immunoglobulin (Ig) E and epidermal thickness were evaluated in both groups. The dermatitis severity was significantly improved by CAP treatment. TEWL was lower in the plasma-treated group compared with the non-treated control group. Serum Ig E dropped significantly after treatment with CAP. Difference in epidermal thickness of the ear skin was not significant between the plasma-treated and non-treated groups. Localized treatment of AD with CAP decreases dermatitis severity, TEWL, and serum Ig E level. These results show CAP’s potentials as a novel therapeutic modality for AD.

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