scholarly journals Acute Generalized Exanthematous Pustulosis with Multiple Organ Failure

2021 ◽  
pp. 47-53
Author(s):  
Tausif Syed ◽  
Abdullah Sayied Abdullah ◽  
Mahmood Mubasher ◽  
Zohaib Yousaf ◽  
Mouhand F.H. Mohamed ◽  
...  
Keyword(s):  
Multiple Organ Failure ◽  
Organ Failure ◽  
Organ Dysfunction ◽  
Multiple Organ ◽  
Circulatory Shock ◽  
Multiple Organ Dysfunction ◽  
Middle Aged ◽  
Acute Generalized Exanthematous Pustulosis ◽  
Limiting Condition ◽  
Exanthematous Pustulosis

Acute generalized exanthematous pustulosis (AGEP) is a rare, self-limiting condition. It presents with sterile skin pustules. We present a middle-aged lady with fluid nonresponsive circulatory shock and multiple organ dysfunction secondary to AGEP.

Modern laboratory biomarkers for diagnosis of dysfunctions of targe organs in syndrome of multiple organ failure

2019 ◽  
Vol 1 (4) ◽  
pp. 37-42
Author(s):  
I. I. Dementieva ◽  
E. V. Kukaeva
Keyword(s):  
Multiple Organ Failure ◽  
Organ Failure ◽  
Organ Dysfunction ◽  
Multiple Organ Dysfunction Syndrome ◽  
Multiple Organ ◽  
Target Organ ◽  
Multiple Organ Dysfunction ◽  
Basic Information ◽  
Early Stages ◽  
Laboratory Biomarkers

This review presents the basic information on the generally pathophysiology of multiple organ dysfunction syndrome and especially the development of target-organ dysfunction. The modern biomarkers that can diagnose organ dysfunction in the early stages of their development.

Multiple Organ Dysfunction Syndrome

2015 ◽  
Author(s):  
Vishal Bansal ◽  
Jay Doucet
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Organ Failure ◽  
Organ Dysfunction ◽  
Multiple Organ Dysfunction Syndrome ◽  
Multiple Organ ◽  
Multiple Organ Dysfunction ◽  
Organ Systems ◽  
Ultimate Outcome

The concept of and approach to multiple organ dysfunction syndrome (MODS), also known as progressive systems failure, multiple organ failure, and multiple system organ failure, have evolved over the last decade. Characterized by progressive but potentially reversible tissue damage and dysfunction of two or more organ systems that arise after a significant physiologic insult and its subsequent management, MODS evolves in the wake of a profound disruption of systemic homeostasis. Pre-existing illness, nutritional status, hospital course, and genetic variation all lead to the development of organ dysfunction in patients exposed to these risk factors. The ultimate outcome from MODS is influenced not only by a patient’s genetic and biological predisposition but also by specific management principles practiced by intensivists. This review details the clinical definitions, quantification, prevention, evaluation, support, and outcomes of organ dysfunction. A figure shows the increasing severity of organ dysfunction correlated with increasing intensive care unit mortality, and an algorithm details the approach to MODS. Tables list risk factors and prognosis for MODS, the multiple organ dysfunction (MOD) score, the sequential organ failure assessment (SOFA) score, intensive care unit interventions that reduce mortality or attenuate organ dysfunction along with unproven or disproven ICU interventions, and the temporal evolution of MODS. This review contains 1 figure, 7 tables, and 159 references.

Sign in / Sign up

Export Citation Format

Share Document