scholarly journals Oncoplastic Surgery in Breast-Conserving Treatment: Patient Profile and Impact on Quality of Life

Breast Care ◽  
2020 ◽  
pp. 1-11
Author(s):  
Idam de Oliveira-Junior ◽  
Igor de Araujo da Silva ◽  
Fabíola Cristina Brandini da Silva ◽  
Jonathas José da Silva ◽  
Almir José Sarri ◽  
...  
2019 ◽  
Author(s):  
René A. C. Vieira ◽  
◽  
Igor A. Silva ◽  
Fabiola C. B. Silva ◽  
Antônio Bailão- Junior ◽  
...  

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Andreas Straube ◽  
Philipp Stude ◽  
Charly Gaul ◽  
Katrin Schuh ◽  
Mirja Koch

Abstract Background Erenumab, the first-in-class fully human monoclonal antibody targeting the calcitonin gene-related peptide receptor, was shown to be efficacious and safe for the prophylactic treatment of migraine in adults in randomized clinical trials. Large-scale, real-world evidence in multi-centre settings is still needed to confirm these results. Erenumab patient profiles outside clinical trials and physicians’ treatment patterns, as well as data from patients treated in Germany, a severely impacted population, are not published yet. Methods TELESCOPE was a multi-centre survey gathering real-world data from 45 German headache centres between July 2019 and December 2019. The project consisted of two parts. In the first part, treating physicians shared their experiences on current erenumab treatment with regard to patient profiles, treatment patterns and treatment responses. In the second part, a retrospective chart review was conducted of 542 migraine patients treated with erenumab for at least three months. Treatment responses focused on various aspects of patients’ quality of life. Results The analysis of 542 patients’ charts revealed that three-month treatment with erenumab significantly reduced monthly headaches, migraine and acute medication days. Furthermore, headache intensity and frequency were reduced in over 75 % and accompanying aura in 35 % of patients. The clinical global impression scale revealed a general improvement in 91 % of patients. According to the treating physicians’ professional judgement, 83 % of patients responded to erenumab and 80 % were satisfied with the treatment. Physicians evaluated restricted quality of life, the number of monthly migraine days and previous, prophylactic treatments as the main components of the current patient profile for monoclonal antibody recipients. Based on the assessment of physicians, erenumab reduced migraine symptoms in 65 % and increased quality of life in more than 75 % of their patients. Conclusions TELESCOPE confirms positive treatment responses with erenumab shown in clinical trials in a real-world multi-centre setting. The results show consistently positive experiences of physicians utilizing erenumab in clinical practice and underline that therapy with this monoclonal antibody is effective in migraine patients, particular in those, who have failed several prophylactic therapies.


Mastology ◽  
2021 ◽  
Vol 31 ◽  
Author(s):  
Idam de Oliveira-Junior ◽  
Raphael Luiz Haikel ◽  
René Aloísio da Costa Vieira

Breast-conserving treatment was established as an oncologically safe procedure for breast cancer. However, the cosmetic outcomes of breast-conserving treatments are often unsatisfactory. In this scenario, oncoplastic breast-conserving surgery incorporated plastic surgery concepts and techniques into the oncological treatment in order to ensure better cosmesis, thus increasing the indications for breast-conserving treatment. At the same time, oncoplastic breast-conserving surgery is usually presented as a generic term, which should be evaluated taking many aspects into account: indication, patient selection, the surgery itself, cosmetic quality, and quality of life — data that are still scarce in the literature.


2009 ◽  
Vol 95 (2) ◽  
pp. 212-218 ◽  
Author(s):  
Zumre Arican Alicikus ◽  
Ilknur Bilkay Gorken ◽  
Rachel Cooper Sen ◽  
Suleyman Kentli ◽  
Munir Kinay ◽  
...  

Author(s):  
Izadora Cristina Bezerra Andrade

Esse estudo teve por objetivo estabelecer o perfil clínico, assim como os diagnósticos de enfermagem mais frequentes e a qualidade de vida dos pacientes no pós-operatório de cirurgia bariátrica. Tratou-se de uma revisão integrativa, no processo de busca, foram usados os descritores período pós-operatório, diagnóstico de enfermagem, obesidade, gastroplastia, com seleção de artigos disponíveis em português, completos, publicados entre 2009 a 2018 que explanaram sobre a temática do estudo. Foram pré-selecionados 20 (vinte) artigos, e utilizados 14 (quatorze), após leitura completa e observação da relação do conteúdo dos artigos ao objetivo do presente trabalho. O perfil dos pacientes foi predominantemente formado por mulheres, jovens adultas, e a comorbidade mais prevalente foi a Hipertensão Arterial Sistêmica (HAS). Os diagnósticos de enfermagem mais frequentes foram débito cardíaco diminuído e dor aguda. A qualidade de vida após a cirurgia no geral foi positiva.Descritores: Período Pós-Operatório, Diagnóstico de Enfermagem, Obesidade, Gastroplastia. After bariatric surgery: integrative reviewAbstract: This study had to objetive  to establish the clinical profile, as well as the most frequent nursing diagnoses and the quality of life of patients in the postoperative period of bariatric surgery. It was an integrative review, in the search process, the following keywords were used: postoperative period, nursing diagnosis, obesity, gastroplasty, with a selection of articles available in Portuguese, complete, published between 2009 and 2018 that explained the study's theme. Twenty (20) articles were pre-selected, and 14 (fourteen) were used, after full reading and observation of the relationship of the content of the articles to the objective of the present work. The patient profile was predominantly made up of women, young adults, the most prevalent comorbidity was Systemic Arterial Hypertension. The most frequent nursing diagnoses were decreased cardiac output and acute pain. The quality of life after surgery in general was positive.Descriptors: Postoperative Period, Nursing Diagnosis, Obesity, Gastroplasty. Postoperatorio cirurgía bariátrica: revisión integrativaResumen: Este estudio tuvo como objetivo establecer el perfil clínico, así como los diagnósticos de enfermería más frecuentes y la calidad de vida de los pacientes en el postoperatorio de cirugía bariátrica. Fue una revisión integradora, en el proceso de búsqueda se utilizaron las siguientes palabras clave: postoperatorio, diagnóstico de enfermería, obesidad, gastroplastia con una selección de artículos disponibles en portugués, completos, publicados entre 2009 y 2018 que explicaban la temática del estúdio. Se preseleccionaron veinte (20) artículos y se utilizaron 14 (catorce), luego de una lectura completa y observación de la relación del contenido de los artículos con el objetivo del presente trabajo. El perfil de los pacientes estuvo compuesto predominantemente por mujeres, adultos jóvenes y la comorbilidad más prevalente fue la Hipertensión Arterial Sistémica. Los diagnósticos de enfermería más frecuentes fueron disminución del gasto cardíaco y dolor agudo. La calidad de vida postoperatoria en general fue positiva.Descriptores: Periodo Posoperatorio, Diagnóstico de Enfermería, Obesidad, Gastroplastia.


2019 ◽  
Vol 37 (4_suppl) ◽  
pp. 24-24 ◽  
Author(s):  
Martha Ann Raymond ◽  
Craig Lustig

24 Background: The World Health Organization estimates 1.03 million new gastric cancer cases will be diagnosed in 2018. Globally, gastric cancer is the 5th most common cancer and the 3rd most common cause of cancer death. Our study explores the gastric cancer survivorship experience throughout the care continuum. Methods: The Ruesch Center for the Cure of Gastrointestinal Cancers and the GI Cancers Alliance developed a global gastric cancer advocacy initiative (December 2017) to better understand the patient experience. As convener, we facilitated numerous meetings with international advocacy organizations; healthcare professionals; patients and caregivers to gain a global perspective. Based on our goal to help improve patient outcomes, our initiative included analysis to support: efforts to increase earlier detection; provide access to best treatment protocols including clinical trials; enhanced patient education and patient-centered communication. A key element of our research began with a global patient survey, focus groups and interviews. Results: 521 gastric cancer patients (54% female 46% male) participated in the international survey (April-May 2018). 49% indicated a ‘poor’ quality of life; 91% indicated survivorship care gaps; 42% were Stage 4. North and South America, Europe, Asia, and Australia were represented. Follow-up interviews and focus groups (July-September 2018) provided valuable insight and a greater understanding of the patient profile. Conclusions: Additional educational and supportive services are needed to meet patient unmet needs. We will continue providing key stakeholder platforms to address patient concerns; create meaningful and relevant patient education; continue outreach leading to increased patient empowerment; convene and work with global partners improving patient quality of life to ultimately achieve better patient outcomes.


Breast Cancer ◽  
1995 ◽  
Vol 2 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Kojiro Shimozuma ◽  
Hiroshi Sonoo ◽  
Kiyoshi Ichihara ◽  
Kazumasa Miyake ◽  
Junichi Kurebayashi ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document