Aberrant Gray Matter Volume and Cortical Surface in Paranoid-Type Delusional Disorder

2020 ◽  
Vol 79 (4-5) ◽  
pp. 335-344
Author(s):  
Robert Christian Wolf ◽  
Viviane Hildebrandt ◽  
Mike M. Schmitgen ◽  
Roger Pycha ◽  
Erwin Kirchler ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Delusional Disorder ◽  
Cortical Surface ◽  
Matter Volume ◽  
Paranoid Type

Regional temporal abnormalities in schizophrenia: A quantitative gray matter volume and cortical surface size study

NeuroImage ◽  
2000 ◽  
Vol 11 (5) ◽  
pp. S197
Author(s):  
Jae-Jin Kim ◽  
Benedicto Crespo-Facorro ◽  
Nancy C. Andreasen ◽  
Daniel S. O'Leary ◽  
Vincent Magnotta
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Cortical Surface ◽  
Matter Volume

scholarly journals Asymmetry Map of Human Brain in Young Adults

2020 ◽  
Author(s):  
Maryam Malekzadeh ◽  
Alireza Kashani
Keyword(s):  
Young Adults ◽  
White Matter ◽  
Human Brain ◽  
Surface Area ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cortical Surface ◽  
Cortical Surface Area ◽  
Matter Volume ◽  
Cortical Regions

AbstractAlthough, asymmetry is a central organizational aspect of human brain, it has not been clearly described yet. Here, we have studied structural brain asymmetry in 1113 young adults using data obtained from Human Connectome Project. A significant rightward asymmetry in mean global cerebral cortical thickness, surface area and gray matter volume as well as volumes of cerebral white matter, cerebellar cortex and white matter, hippocampus, putamen, caudate nucleus, nucleus accumbens and amygdala was observed. Thalamus showed a leftward asymmetry. Regionally, most cerebral cortical regions show a significant rightward asymmetry in thickness. However, cortical surface area and gray matter volume are more evenly distributed between two hemispheres with almost half of the regions showing a leftward asymmetry. In addition, a strong correlation between cortical surface area and gray matter volume as well as their asymmetry indices was noted which results in concordant asymmetry patterns between cortical surface area and gray matter volume in most cortical regions.

Regional frontal abnormalities in schizophrenia: a quantitative gray matter volume and cortical surface size study

2000 ◽  
Vol 48 (2) ◽  
pp. 110-119 ◽  
Author(s):  
Benedicto Crespo-Facorro ◽  
Jae-Jin Kim ◽  
Nancy C Andreasen ◽  
Daniel S O’Leary ◽  
Vincent Magnotta
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Cortical Surface ◽  
Matter Volume

Gray matter volume reduction reflects chronic pain in trigeminal neuralgia

2012 ◽  
Vol 43 (01) ◽  
Author(s):  
M Obermann ◽  
R Rodriguez-Raecke ◽  
S Nägel ◽  
D Holle ◽  
N Theysohn ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Trigeminal Neuralgia ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Volume Reduction ◽  
Matter Volume

scholarly journals Topographic patterns of white matter hyperintensities are associated with multimodal neuroimaging biomarkers of Alzheimer’s disease

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Malo Gaubert ◽  
Catharina Lange ◽  
Antoine Garnier-Crussard ◽  
Theresa Köbe ◽  
Salma Bougacha ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Glucose Metabolism ◽  
Corpus Callosum ◽  
Gray Matter ◽  
Fdg Pet ◽  
White Matter Hyperintensities ◽  
Gray Matter Volume ◽  
Matter Volume

Abstract Background White matter hyperintensities (WMH) are frequently found in Alzheimer’s disease (AD). Commonly considered as a marker of cerebrovascular disease, regional WMH may be related to pathological hallmarks of AD, including beta-amyloid (Aβ) plaques and neurodegeneration. The aim of this study was to examine the regional distribution of WMH associated with Aβ burden, glucose hypometabolism, and gray matter volume reduction. Methods In a total of 155 participants (IMAP+ cohort) across the cognitive continuum from normal cognition to AD dementia, FLAIR MRI, AV45-PET, FDG-PET, and T1 MRI were acquired. WMH were automatically segmented from FLAIR images. Mean levels of neocortical Aβ deposition (AV45-PET), temporo-parietal glucose metabolism (FDG-PET), and medial-temporal gray matter volume (GMV) were extracted from processed images using established AD meta-signature templates. Associations between AD brain biomarkers and WMH, as assessed in region-of-interest and voxel-wise, were examined, adjusting for age, sex, education, and systolic blood pressure. Results There were no significant associations between global Aβ burden and region-specific WMH. Voxel-wise WMH in the splenium of the corpus callosum correlated with greater Aβ deposition at a more liberal threshold. Region- and voxel-based WMH in the posterior corpus callosum, along with parietal, occipital, and frontal areas, were associated with lower temporo-parietal glucose metabolism. Similarly, lower medial-temporal GMV correlated with WMH in the posterior corpus callosum in addition to parietal, occipital, and fontal areas. Conclusions This study demonstrates that local white matter damage is correlated with multimodal brain biomarkers of AD. Our results highlight modality-specific topographic patterns of WMH, which converged in the posterior white matter. Overall, these cross-sectional findings corroborate associations of regional WMH with AD-typical Aß deposition and neurodegeneration.

scholarly journals Voxel-based correlation of 18F-THK5351 accumulation and gray matter volume in the brain of cognitively normal older adults

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yoko Shigemoto ◽  
Daichi Sone ◽  
Miho Ota ◽  
Norihide Maikusa ◽  
Masayo Ogawa ◽  
...  
Keyword(s):  
Older Adults ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cognitively Normal ◽  
Matter Volume ◽  
The Brain
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