The Relationship between Restless Legs Syndrome and Quality of Life in Patients with Myasthenia Gravis

2019 ◽  
Vol 81 (3-4) ◽  
pp. 205-208
Author(s):  
Monica F. Ataide ◽  
Carolina da Cunha-Correia ◽  
Katia C.L. Petribú
Keyword(s):  
Quality Of Life ◽  
Myasthenia Gravis ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Study Population ◽  
Clinical Conditions

Background: Restless legs syndrome (RLS) is characterized for an uncomfortable sensation in legs and an irresistible desire to move them. This disorder has been more recently recognized in patients with myasthenia gravis (MG) and can interfere with the quality of life (QOL). Objectives: The aims of this study are to describe the prevalence of RLS and its severity and influence on the QOL in patients with MG. Method: This was a cross-sectional study conducted from May to June 2016 in Recife, Brazil. A sample of 42 patients was interviewed using a sociodemographic questionnaire, MG QOL questionnaire-15 and The RLS Rating Scale. Results: RLS was present in 47.6% of patients and of these 40.5% met moderate to severe RLS criteria. Patients were 45 years on average (SD ± 14.4) and women represented 57.1% of the study population. Among patients with RSL, the quality-of-life scores were worse (p = 0.010) on average. There was no association of RLS with the duration of MG, use of immunosuppressant or clinical conditions that could mimic the occurrence of RLS. Conclusion: RLS is a prevalent condition in patients with MG, and may be severe enough to negatively impact QOL.

scholarly journals Prevalence of Restless Legs Syndrome among Medical Students of Karachi: An Experience from a Developing Country

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
M. Ishaq ◽  
S. U. Riaz ◽  
N. Iqbal ◽  
S. Siddiqui ◽  
A. Moin ◽  
...  
Keyword(s):  
Medical Students ◽  
Sleep Disturbance ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Smoking Status ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Chief Complaints ◽  
Study Population

Background. Restless legs syndrome (RLS) is a neurological disorder characterized by an uncomfortable sensation in the legs which gets worse in the evening or night, relieved upon movement. The aim of this study was to specify the prevalence of RLS in the group of young medical students and to assess the effect of RLS on sleep, as sleep disturbance is one of the chief complaints of RLS patients. We also studied its association with smoking as it is considered an aggravating factor. Method. This was a cross-sectional study conducted from June 2017 to July 2018 in Karachi. A total of 300 students (220 females and 80 males) participated and were given questionnaires to detect RLS based on criteria proposed by the International Restless Legs Syndrome Study Group. Subjects who were positive for RLS were further asked questions about sleep by using the Epworth Sleepiness Scale and severity of RLS by using RLS Rating Scale. They were also asked about their smoking status. Results. The frequency of RLS is 8% among young adults. Out of 300 medical students, 24 students were classified positive for RLS with a female preponderance (66.7% were females and 33.3% were males). The severity of RLS was more rated to be mild to moderate. The effect of RLS on sleep was in the mild range. The p value of smoking status comparing with gender came out to be <0.001, and p value of RLS is 0.773. Conclusion. It is concluded that we found RLS to be present significantly in our population that is without comorbidities. Our results showed female preponderance and a mild sleep disturbance in our study population. More attention is needed to recognize RLS and to manage the aggravating factors of RLS.

Is restless legs syndrome in Parkinson disease patients associated with any specific factor?

2021 ◽  
Vol 79 (1) ◽  
pp. 38-43
Author(s):  
Manoel Alves SOBREIRA-NETO ◽  
Márcio Alexandre PENA-PEREIRA ◽  
Emmanuelle Silva Tavares SOBREIRA ◽  
Marcos Hortes Nisihara CHAGAS ◽  
Carlos Maurício Oliveira de ALMEIDA ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Lower Limbs ◽  
Specific Factor ◽  
Cross Sectional ◽  
Restless Legs

ABSTRACT Background: Restless legs syndrome or Willis-Ekbom disease is a disorder characterized by unpleasant sensations associated with the need to mobilize the lower limbs. In Parkinson disease patients, restless legs syndrome is associated with worse quality of life and excessive sleepiness. Regarding other factors, results of different studies are controversial. Objective: To determine the factors associated with the restless legs syndrome presence in Parkinson disease patients. Methods: A cross-sectional study was conducted in 88 consecutive Parkinson disease patients from the outpatient clinic for 21 months. Participants underwent a clinical interview, assessment based on standardized scales (Epworth Sleepiness Scale, Parkinson Disease Questionnaire - 39, Pittsburgh Sleep Quality Index, International Restless Legs Syndrome Study Group rating scale), and video-polysomnography. Results: Out of the 88 participants, 25 had restless legs syndrome. In the multivariate analysis, restless legs syndrome in Parkinson disease has been associated with the symptom of smell loss and quality of sleep and life. In the univariate analysis, restless legs syndrome in Parkinson disease has occurred more frequently in women with higher frequency of insomnia, constipation, and anosmia than in the group without restless legs syndrome. Conclusion: Restless legs syndrome is a prevalent condition in patients with Parkinson disease and is associated with specific characteristics in this group of patients.

scholarly journals Prevalence and quality of life in high school pupils with acne in Serbia

2013 ◽  
Vol 70 (10) ◽  
pp. 935-939 ◽  
Author(s):  
Jelena Peric ◽  
Natasa Maksimovic ◽  
Janko Jankovic ◽  
Biljana Mijovic ◽  
Vesna Reljic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High School ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Demographic Questionnaire ◽  
Study Population ◽  
Serbian Version ◽  
The Impact ◽  
Spearman’S Correlation

Background/Aim. Acne is a common problem in adolescent children with considerable emotional and psychological effects. The aim of this study was to determine the self-reported prevalence of acne and to assess its impact on the quality of life in high school pupils in Serbia. Methods. The cross-sectional study was conducted in May 2011 in two medical high schools in Serbia. Only pupils who gave a written informed consent to participate in the study (n = 440) were asked to fill in two questionnaires: short demographic questionnaire and Cardiff Acne Disability Index (CADI), a disease-specific questionnaire measuring disability induced by acne. Internal consistency (tested by Cronbach?s alpha) and item-total score correlations (Spearman's correlation analysis) were used for reliability analyses. Results. The study population consisted of 440 pupils, 281 from Belgrade and 159 from Uzice. Among them 371 (84.3%) were girls and 69 (15.7%) boys, with similar sex distribution in Belgrade and Uzice. The total mean age of pupils was 16.48 years (SD = 0.55). Out of 440 pupils 228 (51.8%) self-reported their acne. The acne prevalence was significantly higher in pupils from Uzice (73.6%) than in those from Belgrade (39.6%). The overall mean CADI score for the whole sample was 2.87 ? 2.74, with the similar quality of life impairment in adolescents from Belgrade and from Uzice. The mean Cronbach?s alpha was 0.82. Conclusion. This study shows that the quality of life impairment due to acne is mild for the majority of the affected pupils. The Serbian version of the CADI is a reliable, valid, and valuable tool for assessing the impact of acne on the quality of life.

scholarly journals Perception of health status and quality of life of people living with HIV in Patan city, Gujarat, India: a cross sectional study

2017 ◽  
Vol 4 (4) ◽  
pp. 1137
Author(s):  
Grishma T. Dixit ◽  
Nilesh Thakor ◽  
Mihir Goswami ◽  
P. B. Verma
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Age Group ◽  
Cross Sectional ◽  
Perceived Satisfaction ◽  
Study Population ◽  
Living With Hiv ◽  
Perception Of Health

Background: Human Immunodeficiency Virus is the biggest threat to the mankind today from their health perspective. To know the perception of health status and quality of life of people living with HIV/AIDS.Methods: This cross sectional study was undertaken during March 2015 to April 2016 at Patan city. After taking permission from NGO and Gujarat State AIDS Control Society (GSACS) total 100 purposively selected People living with HIV (PLHIV) attached to the NGO of Patan city were interviewed using predesigned semi-structured performa. Written informed consent was taken from all PLHIV. Ethical approval was obtained from institutional ethical committee for human research. Data safety and confidentiality was also given due consideration. Data were statistically analyzed using SPSS software (trial version). Results: Age of study population ranges from 18 to 68 years. Mean age of study population is 34.21 + 9.1 years. Maximum number of PLHIV, 51 % are in the age group of 31-40 years age group. Out of total, 76 have perception of being healthy .Out of total, 61 % PLHIV have faced stigma. Out of total,92% were enjoying life, 74% perceived good quality of life, 95% perceived safe in life, 96% perceived satisfaction with health services, 84% perceived  satisfaction with their day to day work capability and only 8% perceived fear about their future life. Conclusions: Positive attitude towards life and health was observed in People Living with HIV. 

scholarly journals Association between quality of life and severity of menopausal symptoms among Saudi women in Al-Ahsa

2021 ◽  
Vol 11 (12) ◽  
pp. 82
Author(s):  
Ola Mousa ◽  
Fatemah M. Alkhars ◽  
Mashael T. Al Shawaf ◽  
Enas A. Al Omran ◽  
Rawan A. Alkhawajah ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rating Scale ◽  
Negative Impact ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Menopausal Symptoms ◽  
Reproductive Age ◽  
Cross Sectional ◽  
Saudi Women

Background and objective: Menopause is not an illness. It is a normal physiologic process at the time that marks the end of the menstrual cycles. The severity, frequency, duration, and impact of these menopausal symptoms vary from woman to woman according to their age, and they affect the overall quality of life. The aim of this study is to verify the severity of menopausal symptoms experienced by Saudi women in Al Ahsa, and to identify the association between the severity of menopausal symptoms and their effects on the quality of life of Saudi women.Methods: An analytical cross- sectional study involved 427 women aged 45-60 years old. They were randomly collected by researchers who interviewed them in outpatient clinics and obstetrics and gynecology wards from 6 hospitals by using the Menopause Rating Scale (MRS) questionnaire and the Menopause Specific Quality of Life (MENQOL) questionnaire between February 15, 2021 and May 15, 2021.Results: The average age of participants was between 45-49. The MRS shows that mild symptoms were found in 47.8% of participants, while severe symptoms were 10.6%. The most common symptoms were physical and somatic. The Menopause Specific Quality of Life shows that 52.2% of the participants suffer from mild bothersome, while 7.5% have extremely bothersome. There was a strong positive association between menopause specific quality of life, and menopausal symptoms.Conclusions: There was a positive correlation between menopausal symptoms and the quality of life of women. Menopausal symptoms have a negative impact on the quality of women's lives. Therefore, the policy makers in the ministry of health could strengthen providing health programmes and health services to women in this age group, besides women in the reproductive age. This can be accomplished by including modules related to the special health needs of menopausal women in the primary center's health programs.

scholarly journals Correlation of Anaemia and Restless Legs Syndrome in Elderly: A Cross-sectional Study

2020 ◽  
Author(s):  
Abhijit Agrawal ◽  
Jahnabi Bhagawati ◽  
Sunil Kumar
Keyword(s):  
Serum Ferritin ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Severe Anaemia ◽  
World Health ◽  
Sectional Study ◽  
Cross Sectional ◽  
Clinical Criteria ◽  
Restless Legs

Introduction: Restless Legs Syndrome (RLS) also known as Willis Ekbom Disease (WED) which manifests as a neurologic disorder among patients with anaemia, particularly with iron deficiency anaemia. Aim: To find the association of anaemia with RLS in the elderly population. Materials and Methods: In this cross-sectional study, 100 patients of age ≥60 years were enrolled and categorised into mild, moderate, and severe anaemia as per World Health Organisation (WHO) criteria. Every participant was enquired about RLS via a questionnaire based on the International RLS Study Group Rating Scale (IRLSSGRS) for its Severity and for the diagnosis (Essential clinical criteria for the diagnosis of RLS). Results: The study showed that patients with anaemia had a statistically significant correlation with RLS (p=0.04) and severity of RLS (p=0.032). Serum ferritin levels too showed a statistically significant correlation with RLS (p=0.032). Conclusion: Patients with severe anaemia and lower serum ferritin levels were more prone to RLS and had more RLS severity.

Pruritus and Malodour in Patients with Hidradenitis Suppurativa: Impact on Quality of Life and Clinical Features Associated with Symptom Severity

Dermatology ◽  
2019 ◽  
Vol 236 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Alejandro Molina-Leyva ◽  
Carlos Cuenca-Barrales
Keyword(s):  
Quality Of Life ◽  
Clinical Features ◽  
Hidradenitis Suppurativa ◽  
Rating Scale ◽  
Life Quality ◽  
Numeric Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
The Impact

Background: Patients with hidradenitis suppurativa (HS) suffer from symptoms such as pruritus and malodour which can significantly impair their quality of life. Objectives: (1) To analyse the impact of pruritus and malodour on the quality of life of patients with HS and (2) to explore the potential association between clinical features and the severity of these symptoms. Patients and Methods: This is a cross-sectional study. The Numeric Rating Scale (NRS) was used to assess pruritus and malodour. Quality of life was assessed by means of the Dermatology Life Quality Index (DLQI). Results: Two hundred and thirty-three patients were included in the study. Both pruritus and malodour positively correlated with worse quality of life (p < 0.05). Pruritus intensity was associated with the number of regions affected by HS, female sex, the intensity of suppuration, and the presence of comorbid Crohn’s disease. Statin use was associated with lower levels of pruritus. Malodour intensity was associated with higher body mass index, disease duration, the number of regions affected, Hurley stage, and intensity of suppuration. Conclusions: The results of our study show that pruritus and malodour are key symptoms in patients with HS which have a great impact on their quality of life. We have identified clinical features potentially associated with the intensity of these symptoms which could be useful to identify higher-risk patients and may influence treatment decisions.

scholarly journals Online assessment of the perception of loneliness and associated factors in Colombian climacteric women during the COVID-19 pandemic: A cross-sectional study

2021 ◽  
Vol 11 (2) ◽  
pp. 230-239
Author(s):  
Angélica Monterrosa-Blanco ◽  
Álvaro Monterrosa-Castro ◽  
Andrea González-Sequeda
Keyword(s):  
Quality Of Life ◽  
Associated Factors ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Middle Aged ◽  
Cross Sectional ◽  
Colombian Women ◽  
Severe Deterioration

Background: The coronavirus disease 2019 (COVID-19) pandemic has generated changes due to confinement, this measure can increase the perception of loneliness. The objective was to estimate the frequencies of emotional, social and general loneliness and their association with fear and anxiety with COVID-19, religiosity and severe deterioration of quality of life in middle-aged women. Methods: A cross-sectional study in Colombian women (40-59 y, n=984) surveyed with an electronic form that included sociodemographic characteristics and validated measures (Menopause Rating Scale, de Jong Gierveld Loneliness Scale, fear of COVID-19 scale, Coronavirus Anxiety Scale and Francis Scale for Religiosity). Associations of emotional, social and general loneliness (dependent variables) with severe somatic, psychological, urogenital and quality of life deterioration, as well as with high religiosity, anxiety and high fear of COVID-19 (independent variables), were estimated. Results: The median age was 47 years old, and 39.2% [95% CI: 36.2-42.3] postmenopausal. Severe deterioration in somatic, psychological, urogenital domains and quality of life in women with emotional, social and general loneliness was found (P<0.001). In adjusted models, high fear of COVID-19, severe deterioration of psychological and urogenital domains and quality of life were associated with emotional, social and general loneliness. Anxiety with COVID-19, somatic domain and high religiosity were not associated with loneliness. Conclusion: Emotional, social and general loneliness were identified in 4/10 middle-aged Colombian women surveyed, and the associated factors were high fear of COVID-19, severe deterioration of quality of life and psychological and urogenital domains. Professionals who care for climacteric women should explore the perception of loneliness when assessing menopausal symptoms.

scholarly journals Quality of life among elderly population in an urban slum of Tirupati city

2019 ◽  
Vol 6 (6) ◽  
pp. 2430
Author(s):  
Visweswara Rao Guthi ◽  
Tirupati Venkata Devi Prathyusha ◽  
Nagaraj Kondagunta ◽  
Nakkala Kavyasree ◽  
Chimmata Kavitha ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Healthy Aging ◽  
Elderly Population ◽  
Well Being ◽  
The Elderly ◽  
Urban Slum ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Study Population

Background: Healthy aging is a process of developing and maintaining the functional ability that enables well- being in older age. Objective of the present study is to assess the quality of life among elderly population using WHOQOL-BREF scale and to determine the association between socio demographic factors and quality of life.Methods: Community based cross- sectional study was conducted in the urban field practice areas of SVIMS-Sri Padmavathi Medical College for women, Tirupati for a period of one month (February 2019 to March 2019). Study population were Elderly of age 60 years and above. Total 60 elderly were included in the study. Quality of life was assessed using WHOQOL-BREF questionnaire.Results: Most of the study population was in the age group of 60-64 years, Most of them were females (71.7%). More than one third were illiterates (36.7%), 30% were studied up to primary school. 93.3% of study population were suffered from some form of illness. Mean total transformed score was high among ≥70 years compared to <70 years, Males were showing high mean total transformed score compared to females, literates were showing high score and persons with illness were showing high scores and persons without illness.Conclusions: It is concluded from this study that most of the elderly population are suffered from some form of illness. Overall quality of life is good among elderly within 70 years of age, males, literates and who are in living as married compared to their counter parts.

scholarly journals 0615 The Prevalence of Common Sleep Disorders In Young Adults: A Population-Based Study

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A235-A236
Author(s):  
P R Eastwood ◽  
S V Ward ◽  
R S Bucks ◽  
K Maddison ◽  
A Smith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Sleep Disorders ◽  
Restless Legs Syndrome ◽  
Survey Methods ◽  
Cross Sectional ◽  
Female Ratio ◽  
Periodic Leg Movements ◽  
Restless Legs

Abstract Introduction Adult sleep disorders are associated with adverse health effects including reduced quality of life and increased mortality. However, there is a paucity of data on sleep disorders in young adulthood. Methods We undertook a cross-sectional observational study of 1,227 young adults participating in the Western Australian Pregnancy (Raine) Study (2012-2014) to describe the prevalence of common sleep disorders in young adults. We used in-laboratory polysomnography (PSG) and validated survey methods, including the Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Symptom Questionnaire-Insomnia and International Restless Legs Syndrome Study Group criteria. 1,146 completed a core questionnaire, 1,051 completed a sleep-focused questionnaire and 935 had analysable PSG data. Results Participants had a mean age of 22.2 years and male to female ratio of 1 to 1.1. The prevalence of OSA [apnoea hypopnoea index (AHI): ≥5events/hour] was 20.8% (95%CI: 18.2 to 23.6) and this was usually of mild severity (AHI:≥5 to&lt;15events/hour, 17.1%). OSA syndrome (AHI≥5 events/hour and ESS≥11) was found in 2.8% (95%CI: 1.9 to 4.1). Chronic insomnia was present in 16.6% (95%CI: 14.7 to 19.4). Restless legs syndrome was present in 2.9% (95%CI: 2.0 to 4.0) and abnormal periodic leg movements during sleep (&gt;5 movements/hour) in 9.1% (95%CI: 7.3 to 11.1). In those participants who had complete data on all sleep-related assessments (n=841), at least one sleep disorder was present in 42.6%. Conclusion Sleep disorders are very common in young adults. Health practitioners should be aware of these high prevalences, as early identification and treatment can improve quality of life and may reduce later morbidity and mortality. Support  

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