Pruritus and Malodour in Patients with Hidradenitis Suppurativa: Impact on Quality of Life and Clinical Features Associated with Symptom Severity

Dermatology ◽  
2019 ◽  
Vol 236 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Alejandro Molina-Leyva ◽  
Carlos Cuenca-Barrales
Keyword(s):  
Quality Of Life ◽  
Clinical Features ◽  
Hidradenitis Suppurativa ◽  
Rating Scale ◽  
Life Quality ◽  
Numeric Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
The Impact

Background: Patients with hidradenitis suppurativa (HS) suffer from symptoms such as pruritus and malodour which can significantly impair their quality of life. Objectives: (1) To analyse the impact of pruritus and malodour on the quality of life of patients with HS and (2) to explore the potential association between clinical features and the severity of these symptoms. Patients and Methods: This is a cross-sectional study. The Numeric Rating Scale (NRS) was used to assess pruritus and malodour. Quality of life was assessed by means of the Dermatology Life Quality Index (DLQI). Results: Two hundred and thirty-three patients were included in the study. Both pruritus and malodour positively correlated with worse quality of life (p < 0.05). Pruritus intensity was associated with the number of regions affected by HS, female sex, the intensity of suppuration, and the presence of comorbid Crohn’s disease. Statin use was associated with lower levels of pruritus. Malodour intensity was associated with higher body mass index, disease duration, the number of regions affected, Hurley stage, and intensity of suppuration. Conclusions: The results of our study show that pruritus and malodour are key symptoms in patients with HS which have a great impact on their quality of life. We have identified clinical features potentially associated with the intensity of these symptoms which could be useful to identify higher-risk patients and may influence treatment decisions.

scholarly journals Quality of Life in Cohabitants of Patients with Hidradenitis Suppurativa: A Cross-sectional Study

2020 ◽  
Vol 17 (16) ◽  
pp. 6000 ◽  
Author(s):  
Carmen Ramos-Alejos-Pita ◽  
Salvador Arias-Santiago ◽  
Alejandro Molina-Leyva
Keyword(s):  
Quality Of Life ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Hidradenitis Suppurativa ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type D

Hidradenitis suppurativa (HS) is a chronic inflammatory disease that impairs patients’ physical and mental health. However, few studies have considered the consequences of HS on cohabitants. The aims of this study were to explore the impact of HS on the quality of life (QOL) of cohabitants and to assess potentially associated factors. A cross-sectional study was conducted and patients with HS and their cohabitants were invited to participate. Validated questionnaires were used to measure QOL, anxiety and depression, type D personality and sexual dysfunction. The clinical variables of patients and the demographic characteristics of cohabitants were also collected. Twenty-seven patients and 27 cohabitants were included for analysis. Patients and cohabitants presented significant QOL impairment. A direct association was found between the Dermatology Life Quality Index (DLQI) and the Familiar Dermatology Life Quality Index (FDLQI). DLQI scores were associated with the presence of negative affectivity, a trait typical of type D personality, as well as with cohabitants’ anxiety. FDLQI scores were associated with cohabitant anxiety and patient depression. Hidradenitis suppurativa damages quality of life in patients and cohabitants. Identifying potential psychological factors could help us to recognize at-risk patients and apply personalized treatments for them and their environment.

scholarly journals Quality of life during the epidemic of COVID-19 and its associated factors among enterprise workers in East China

2020 ◽  
Author(s):  
Xiaoxiao Chen ◽  
Qian Xu ◽  
Haijiang Lin ◽  
Jianfu Zhu ◽  
Yue Chen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Associated Factors ◽  
Large Scale ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Related Factors ◽  
Cross Sectional ◽  
Home Ventilation ◽  
The Impact

Abstract Background: The COVID-19 related lockdown and home confinement might have an important impact on the quality of life in enterprise workers. We investigated the quality of life during the epidemic in enterprise workers who just returned to work, and assessed its potential influencing factors to have a better understanding of the impact of COVID-19 epidemic lockdown and home confinement. Methods: This was a cross-sectional study of enterprise workers conducted in Deqing and Taizhou, Zhejiang Province, China. The Chinese version of EQ5D was used to assess life quality, and information about general characteristics and COVID-19 related factors was collected by a structured questionnaire, which was distributed through the social application “WeChat”. Results: A total of 2,435 participants were enrolled, 59.5% of which worked in Deqing. About 50% of the participants reported worries about the COVID-2019 epidemic and 40.1% had a centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression showed that the quality of life measures was related to physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) in Deqing, and were related to wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and having a centralized or home quarantine (ORad=1.64) in Taizhou,Conclusions: The quality of life for returning enterprise workers in areas with different risks of COVID-19 was affected by different factors. Associated factors identified from this study would help develop proper intervention measures for enterprise workers to reduce the impact of large-scale public health events like the COVID-19 on their quality of life.

scholarly journals Quality of life during the epidemic of COVID-19 and its associated factors among enterprise workers in East China

2020 ◽  
Author(s):  
Xiaoxiao Chen ◽  
Qian Xu ◽  
Haijiang Lin ◽  
Jianfu Zhu ◽  
Yue Chen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Associated Factors ◽  
Large Scale ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Related Factors ◽  
Cross Sectional ◽  
Home Ventilation ◽  
The Impact

Abstract Background: The COVID-19 related lockdown and home confinement might have an important impact on the quality of life in enterprise workers. We investigated the quality of life during the epidemic in enterprise workers who just returned to work, and assessed its potential influencing factors to have a better understanding of the impact of COVID-19 epidemic lockdown and home confinement.Methods: This was a cross-sectional study of enterprise workers conducted in Deqing and Taizhou, Zhejiang Province, China. The Chinese version of EQ5D was used to assess life quality, and information about general characteristics and COVID-19 related factors was collected by a structured questionnaire, which was distributed through the social application “WeChat”.Results: A total of 2,435 participants were enrolled, 59.5% of which worked in Deqing. About 50% of the participants reported worries about the COVID-2019 epidemic and 40.1% had a centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression showed that the quality of life measures was related to physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) in Deqing, and were related to wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and having a centralized or home quarantine (ORad=1.64) in Taizhou,Conclusions: The quality of life for returning enterprise workers in areas with different risks of COVID-19 was affected by different factors. Associated factors identified from this study would help develop proper intervention measures for enterprise workers to reduce the impact of large-scale public health events like the COVID-19 on their quality of life.

scholarly journals Quality-of-Life Impairment among Patients with Hidradenitis Suppurativa: A Cross-Sectional Study of 1795 Patients

Life ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 34
Author(s):  
Piotr K. Krajewski ◽  
Łukasz Matusiak ◽  
Esther von Stebut ◽  
Michael Schultheis ◽  
Uwe Kirschner ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Demographic Data ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Score System ◽  
Holistic Management ◽  
Inflammatory Skin Disorder

The chronic, inflammatory skin disorder hidradenitis suppurativa (HS) is associated well documented negative influences on patients’ quality of life (QoL). The aim of this study was to present more robust data on patients’ QoL impairment by demographic data and its correlation with well-known HS risk factors on a cohort of 1795 German patients. The instrument used for measuring QoL in this study was the Dermatology Life Quality Index (DLQI). Overall, patients reported a very large effect of HS on their QoL (mean DLQI: 13.2 ± 8.1 points), and 22% of the analyzed population even reported to consider the effect as extremely large. Women tended to experience significantly higher impairment than men (p < 0.001). QoL impairment correlated positively with pain (r = 0.581, p < 0.001), HS severity (measured by the International Hidradenitis Suppurativa Severity Score System (IHS4)) as well as Hurley. Neck involvement tended to decrease QoL significantly more than any other location (14.7 ± 8.3 points). This study confirms the enormous influence of HS on patients’ QoL in a large cohort. Knowledge of QoL impairment in such patients is crucial for proper understanding and holistic management of this disease.

scholarly journals Influence of dermatophytosis on quality of life: a cross sectional study from Kashmir Valley in North India

2020 ◽  
Vol 7 (5) ◽  
pp. 1711
Author(s):  
Shahnawaz Bashir ◽  
Iffat Hassan ◽  
Rabbanie T. Wani
Keyword(s):  
Quality Of Life ◽  
Life Quality ◽  
Cross Sectional Study ◽  
North India ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Impairment ◽  
Relationship Of ◽  
The Impact

Background: Over the past few years, dermatophytosis tends to be prolonged and persistent which negatively affects quality of life and relationship of patients with other people. There is limited literature available on the impact of dermatophytosis on the quality of life (QoL). The aim of the study is to investigate the influence of dermatophytosis on QoL in affected patients and identifying the risk factors associated therein.Methods: This was a cross-sectional study (descriptive study) in which 425 patients aged ≥18 years with dermatophytosis were included and evaluated for impact on QoL using dermatology life quality index (DLQI) questionnaire. Modified Kuppuswamy scale was also used for assessing the socioeconomic status of the study subjects. Independent t-test and ANOVA were used to find statistical associations between mean DLQI scores and various variables, wherever applicable.Results: The mean DLQI score in our study was 13.93±6.26. Dermatophytosis was found to have a very large effect on the QoL in majority (55.5%) of our subjects followed by moderate effect in 29.5% cases. Mean DLQI was higher in patients with longer duration of disease, involvement of unexposed sites (groins, gluteal region, axillae), greater number of sites involved, more body surface area involved, pruritus, redness and burning sensation (p<0.05). Regarding socio-demographic related variables, Mean DLQI score was higher in females, rural people, in (20-39) years age group, and in patients belonging to upper middle class (p<0.05).Conclusions: This study revealed significant impairment of QoL patients with dermatophytosis.

scholarly journals Sexual Distress in Patients with Hidradenitis Suppurativa: A Cross-Sectional Study

2019 ◽  
Vol 8 (4) ◽  
pp. 532 ◽  
Author(s):  
Carlos Cuenca-Barrales ◽  
Ricardo Ruiz-Villaverde ◽  
Alejandro Molina-Leyva
Keyword(s):  
Hidradenitis Suppurativa ◽  
Rating Scale ◽  
Multiple Linear Regression Model ◽  
Numeric Rating Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Sexual Distress ◽  
The Impact

Hidradenitis suppurativa (HS) is a chronic auto-inflammatory skin disease with a great impact in quality of life. However, there is little research about the impact of HS on sex life. The aims of this study are to describe the frequency of sexual distress (SD) in patients with HS and to explore potentially associated epidemiological and clinical factors. We conducted a cross-sectional study by means of a crowd-sourced online questionnaire hosted by the Spanish hidradenitis suppurativa patients’ association (ASENDHI). Sexual distress (SD) was evaluated with a Numeric Rating Scale (NRS) for HS impact on sex life. A total of 393 participants answered the questionnaire. The mean NRS for HS impact on sex life was 7.24 (2.77) in women and 6.39 (3.44) in men (p < 0.05). Variables significantly associated (p < 0.05) with SD in the multiple linear regression model were sex, with a higher risk in females, the presence of active lesions in the groin and genitals and NRS for pain and unpleasant odor; being in a stable relationship was an important protector factor. Regarding these results, it seems that SD in HS patients is due, at least in part, to disease symptoms and active lesions in specific locations, emphasizing the importance of disease control with a proper treatment according to management guidelines. Women and single patients are more likely to suffer from sexual distress.

scholarly journals Quality of life during the epidemic of COVID-19 and its associated factors among enterprise workers in East China

2020 ◽  
Author(s):  
Xiaoxiao Chen ◽  
Qian Xu ◽  
Haijiang Lin ◽  
Jianfu Zhu ◽  
Yue Chen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Home Ventilation ◽  
Related Information ◽  
The Social ◽  
Questionnaire Online ◽  
The Impact

Abstract Background: The impact of COVID-19 related quarantine on quality of life was expected and unclear for enterprise workers. We investigated the quality of life during the epidemic in enterprise workers just returned to work and assessed its potential influencing factors to get a better understanding of the impact of COVID-19 epidemic. Methods: This was a cross-sectional study among enterprise workers in Deqing and Taizhou, Zhejiang Province, China. Chinese version of EQ5D to assess life quality, and information about general characteristics and COVID-19 related information was collected by a structured questionnaire online distributed through the social application “Wechat”. Results: A total of 2435 participants were enrolled, 59.5% of which worked in Deqing. About 50% reported worries about the COVID-2019 epidemic and 40.1% of participants performed centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression suggested that physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) was related with life quality in Deqing, while for participants in Taizhou, wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and experienced centralized or home quarantine (ORad=1.64) was related with quality of life.Conclusions: Enterprise workers in two areas with different risk of COVID-19 experienced different life quality during the epidemic of COVID-19. Physical activity, marital status, worry about epidemic of COVID-19, keeping home ventilation, wearing a mask and quarantine were related with quality of life.

scholarly journals Evaluation of the quality of life in adolescents with acne

2014 ◽  
Vol 71 (7) ◽  
pp. 634-638 ◽  
Author(s):  
Vesna Reljic ◽  
Natasa Maksimovic ◽  
Janko Jankovic ◽  
Biljana Mijovic ◽  
Jelena Peric ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Demographic Questionnaire ◽  
Study Population ◽  
Practical Tool ◽  
The Mean ◽  
The Impact

Background/Aim. Acne is well recognized condition that adversely affects quality of life (QoL) of the patients. The aim of this study was to determine the self-reported prevalence of acne and its main characteristics in high school pupils, and to assess their QoL. Methods. The cross-sectional study conducted in May 2011 comprised 440 pupils from Serbia (281 from Belgrade and 159 from Uzice). Participation in the study was voluntary and anonymous. Two questionnaires were administered: a short demographic questionnaire, and Children's Dermatology Life Quality Index (CDLQI). Internal consistency was assessed using the Cronbach?s alpha while item-total score correlations were assessed using Spearman's correlation analysis. Results. The majority of the study population (84.3%) were girls, and 15.7% were boys. The total mean age of the pupils was 16.48 ? 0.55 years. A total of 228 (51.8%) pupils self-reported their acne with significantly higher prevalence in Uzice (73.6%) than in Belgrade (39.5%). The mean CDLQI score was 3.55 with the similar quality of life impairment in adolescents from the two cities. The mean Cronbach?s alpha was 0.83. There was a statistically significant positive correlation between the mean overall CDLQI score and CDLQI subscale scores that ranged from 0.401 to 0.841. Conclusion. Our study confirmed that acne is associated with impairment in QoL that is in accordance with previous studies performed on teenagers. The CDLQI is a reliable and valid measure, and can be used as a practical tool for measuring the impact of acne on patients? QoL.

Health related quality of life of rosacea patients in China assessed by DLQI and willingness to pay: Cross-Sectional Questionnaire Study (Preprint)

2020 ◽  
Author(s):  
Yaqun Huang ◽  
Sha Yan ◽  
Hongfu Xie ◽  
Ben Wang ◽  
Zhixiang Zhao ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Willingness To Pay ◽  
Disease Duration ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

BACKGROUND Rosacea is a chronic inflammatory dermatosis with facial skin involved, leading to physical and emotional problems, which greatly affected quality of life (QoL) of patients. Dermatology Life Quality Index (DLQI) and willingness to pay (WTP) are well-established instruments assessing the health-related quality of life (HRQoL), while very few studies have been focused on this topic about rosacea in China. OBJECTIVE To investigate HRQoL in Chinese rosacea patients assessed by DLQI and WTP and investigate potential predictors for patients with HRQoL severely affected. METHODS This cross-sectional study was conducted on 973 patients with rosacea. Sociodemographic data, clinical features and DLQI were collected, and WTP was assessed by three standardized items. Multivariable logistic analysis was performed to investigate independent factors influencing QoL. RESULTS 921 questionnaires were accomplished by participants. The mean DLQI score was 11.6 (median 11). Patients were willing to pay an average of $1050.2 or € 896.2 (median $431.4 or € 368.1) for complete cure. 33.3% would like to pay more than 20% of their monthly income to achieve sustainable control. There were positive correlations between WTP with DLQI (P < .05). DLQI could be independently impacted by age (21-30 and 31-40, OR = 3.242 and 3.617, respectively), the occupational requirement of appearance (high, OR = 4.410), disease duration (< 2 years, OR = 1.582), oedema (OR = 1.844) and severity of flushing, burning, stinging and pruritus (severe, OR = 2.003, 1.981, 2.491, 2.249, respectively). There were no significant associations between WTP and most of the clinical factors. CONCLUSIONS The QoL was negatively affected and should not be ignored among rosacea patients in China. Patients aged 21-40y, having occupational requirement of appearance, with the disease duration less than 2 years, and suffering severe flushing and related symptoms were more likely to have severe or very severe limitation of QoL.

scholarly journals Quality of Life Prior and in the Course of the COVID-19 Pandemic: A Nationwide Cross-Sectional Study with Brazilian Dietitians

2021 ◽  
Vol 18 (5) ◽  
pp. 2712
Author(s):  
Raquel Adjafre da Costa Matos ◽  
Rita de Cassia Coelho de Almeida Akutsu ◽  
Renata Puppin Zandonadi ◽  
Raquel Braz Assunção Botelho
Keyword(s):  
Quality Of Life ◽  
Psychological Health ◽  
Social Relationship ◽  
Healthcare Professionals ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chi Squared

Dietitians as healthcare professionals could decrease their quality of life during the SARS-COV-2 pandemic period; therefore, this study aimed to compare Brazilian dietitians’ perceptions of quality of life before and during the pandemic. This nationwide cross-sectional research aimed to evaluate Brazilian dietitians’ quality of life before and in the course of the COVID-19 pandemic, using a previously validated self-administered instrument WHO-QOL-BREF in Brazilian-Portuguese. The questionnaire was composed of 26 items (four domains) to evaluate life quality (physical, psychological, social relationship, and environment). The questionnaire also presented some sociodemographic variables and three questions about the COVID-19 pandemic. It was applied using GoogleForms® platform (Google LLC, Mountain View, CA, USA). For the statistical analysis of data, Paired T-test, Chi-squared test, and Analysis of Variance were used. A total of 1290 Brazilian dietitians replied to the instrument. Comparing quality of life (QoL) before SARS-COV-2 (3.83 ± 0.59) and during the pandemic (3.36 ± 0.66), data was statistically different. Comparing prior and in the course of the COVID-19 pandemic, all variables and domains presented statistical differences (better before the pandemic period). Among Brazilian dietitians, the psychological health domain was the most affected. The Sars-Cov-2 pandemic negatively impacted the QoL of Brazilian dietitians since health professionals face changes in their lives because of work.

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