scholarly journals Endosonographic Appearances of a Rare Duodenal Tumour, Brunner’s Gland Hamartoma

2019 ◽  
Vol 13 (2) ◽  
pp. 310-320
Author(s):  
Ikram Hussain ◽  
Malcolm Tan ◽  
Meyyur Aravamudan Veeraraghavan ◽  
Lai Mun Wang ◽  
Andrew Eu Boon Kwek
Keyword(s):  
Gastrointestinal Bleeding ◽  
Surgical Resection ◽  
Rare Case ◽  
Gastrointestinal Symptoms ◽  
Young Female ◽  
Major Surgery ◽  
Epithelial Tumour ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma

Brunner’s gland hamartoma (BGH) is a rare sub-epithelial tumour of the duodenum, which may cause haemorrhagic or obstructive gastrointestinal symptoms. Their accurate histological diagnosis often remains elusive before resection. Although endoscopic ultrasonography (EUS) is considered an excellent modality to study lesions within the gastrointestinal wall, only a few reports have described endosonographic characteristics of BGHs. A reliable pre-resection diagnosis with EUS may not only allay fear of malignancy but may as well avert a major surgery for the patients. In this report, we present a rare case of a large BGH in a young female who presented with acute gastrointestinal bleeding. Here, the endosonographic features assuaged the concern for malignancy while aiding in complete and uneventful surgical resection of the tumour via a submucosal plane.

scholarly journals Giant Brunner’s Gland Hamartoma of the Duodenal Bulb Presenting with Upper Gastrointestinal Bleeding and Obstruction

2016 ◽  
Vol 49 (6) ◽  
pp. 570-574 ◽  
Author(s):  
Ju Hyoung Lee ◽  
Kyeong Min Jo ◽  
Tae Oh Kim ◽  
Jong Ha Park ◽  
Seung Hyun Park ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Duodenal Bulb ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma ◽  
Upper Gastrointestinal

scholarly journals Acute Pancreatitis and Upper Gastrointestinal Bleeding as Presenting Symptoms of a Duodenal Brunner’s Gland Hamartoma

2006 ◽  
Vol 20 (8) ◽  
pp. 541-542 ◽  
Author(s):  
Edy Stermer ◽  
Nizar Elias ◽  
Dean Keren ◽  
Tova Rainis ◽  
Omer Goldstein ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
English Literature ◽  
Presenting Symptoms ◽  
Acute Upper Gastrointestinal Bleeding ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma ◽  
Upper Gastrointestinal

Brunner’s gland hamartomas are rare, benign small bowel tumours. There were fewer than 150 cases reported in the English literature until the end of the last century. These hamartomas may be discovered incidentally during an upper gastrointestinal tract endoscopy. Otherwise, they may be diagnosed in patients presenting with acute upper gastrointestinal bleeding, anemia or symptoms of intestinal obstruction. The case of a young woman admitted for acute upper gastrointestinal bleeding along with acute pancreatitis is presented. The investigation revealed a giant Brunner’s gland hamartoma in the second part of the duodenum. After total endoscopic resection of the tumour, the patient has remained completely asymptomatic for a follow-up period of seven months.

scholarly journals Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature

2002 ◽  
Vol 16 (5) ◽  
pp. 309-313 ◽  
Author(s):  
David R Stolpman ◽  
Gordon C Hunt ◽  
Brett Sheppard ◽  
Hahn Huang ◽  
Deepak V Gopal
Keyword(s):  
Gastrointestinal Bleeding ◽  
Endoscopic Ultrasound ◽  
Deficiency Anemia ◽  
Normal Range ◽  
Ferritin Concentration ◽  
The Third ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma ◽  
Upper Gastrointestinal

An unusual cause of upper gastrointestinal bleeding is described in a previously healthy 45-year-old man who was admitted to hospital with weakness and fatigue, and had experienced an episode of melena two days before admission. His medical and surgical history was unremarkable. Upon admission to hospital, he showed evidence of iron-deficiency anemia, with a hemoglobin concentration of 61 g/L (normal range 135 to 175 g/L), a mean corpuscular volume of 73 fL (normal range 85.0 to 95.0 fL) and a ferritin concentration of 1.0 µg/L (normal range in males 15 to 400 µg/L). Upper gastrointestinal endoscopy revealed a 3.5 cm ulcerated submucosal mass in the third portion of the duodenum, for which mucosal biopsies were nondiagnostic. A subsequent endoscopic ultrasound revealed a 2.7×4.0 cm hyperechoic, cystic, submucosal tumour in the third portion of the duodenum. Endoscopic ultrasound-guided fine needle aspiration revealed no malignant cells. The patient eventually underwent a resection of the third portion of his duodenum. Surgical pathology revealed that this tumour was a Brunner’s gland hamartoma, 4.5 cm in its greatest dimension.

scholarly journals Fatal Gastrointestinal Hemorrhage in a Patient with Brunner’s Gland Hyperplasia

2017 ◽  
Vol 11 (2) ◽  
pp. 411-415 ◽  
Author(s):  
Edward Meltser ◽  
Matthew Federici ◽  
Robert Cooper II ◽  
Cristina Capanescu ◽  
Kathryn C. Behling
Keyword(s):  
Gastrointestinal Bleeding ◽  
Surgical Resection ◽  
Gastrointestinal Hemorrhage ◽  
Malignant Potential ◽  
Histologic Examination ◽  
Ulcer Formation ◽  
Mucosal Ulceration ◽  
Brunner’S Gland ◽  
Clinical Associations ◽  
Brunner's Gland

Brunner’s gland hyperplasia is a rare cause of duodenal mass and gastrointestinal hemorrhage. Imaging and esophagoduodenoscopic evaluation of this condition are frequently consistent with a duodenal malignancy often resulting in surgical resection. However, the malignant potential of these lesions is still unknown, and most are benign. We report the case of a 74-year-old man who presented with fatal gastrointestinal bleeding and esophagoduodenoscopy findings consistent with a duodenal mass and mucosal ulceration. At autopsy, histologic examination of the mass revealed Brunner’s gland hyperplasia with associated ulcer formation. In this report, we review the findings associated with this case as well the literature regarding presentation, clinical associations, and treatment of Brunner’s gland hyperplasia.

scholarly journals A Large Brunner’s Gland Hamartoma Causing Gastrointestinal Bleeding and Obstruction

2007 ◽  
Vol 24 (6) ◽  
pp. 450-452 ◽  
Author(s):  
L.C.F. de Nes ◽  
F. Ouwehand ◽  
S.H.A. Peters ◽  
M.J. Boom
Keyword(s):  
Gastrointestinal Bleeding ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma

scholarly journals A SURGICAL CASE OF BRUNNER'S GLAND HAMARTOMA WITH GASTROINTESTINAL BLEEDING

2004 ◽  
Vol 65 (5) ◽  
pp. 1253-1257
Author(s):  
Yoshito WADA ◽  
Ryo MIYAZAKI ◽  
Junji WADA ◽  
Tomoyo KANEKO ◽  
Motomichi TORISU
Keyword(s):  
Gastrointestinal Bleeding ◽  
Surgical Case ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma
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