scholarly journals Fatal Gastrointestinal Hemorrhage in a Patient with Brunner’s Gland Hyperplasia

2017 ◽  
Vol 11 (2) ◽  
pp. 411-415 ◽  
Author(s):  
Edward Meltser ◽  
Matthew Federici ◽  
Robert Cooper II ◽  
Cristina Capanescu ◽  
Kathryn C. Behling
Keyword(s):  
Gastrointestinal Bleeding ◽  
Surgical Resection ◽  
Gastrointestinal Hemorrhage ◽  
Malignant Potential ◽  
Histologic Examination ◽  
Ulcer Formation ◽  
Mucosal Ulceration ◽  
Brunner’S Gland ◽  
Clinical Associations ◽  
Brunner's Gland

Brunner’s gland hyperplasia is a rare cause of duodenal mass and gastrointestinal hemorrhage. Imaging and esophagoduodenoscopic evaluation of this condition are frequently consistent with a duodenal malignancy often resulting in surgical resection. However, the malignant potential of these lesions is still unknown, and most are benign. We report the case of a 74-year-old man who presented with fatal gastrointestinal bleeding and esophagoduodenoscopy findings consistent with a duodenal mass and mucosal ulceration. At autopsy, histologic examination of the mass revealed Brunner’s gland hyperplasia with associated ulcer formation. In this report, we review the findings associated with this case as well the literature regarding presentation, clinical associations, and treatment of Brunner’s gland hyperplasia.

scholarly journals Endosonographic Appearances of a Rare Duodenal Tumour, Brunner’s Gland Hamartoma

2019 ◽  
Vol 13 (2) ◽  
pp. 310-320
Author(s):  
Ikram Hussain ◽  
Malcolm Tan ◽  
Meyyur Aravamudan Veeraraghavan ◽  
Lai Mun Wang ◽  
Andrew Eu Boon Kwek
Keyword(s):  
Gastrointestinal Bleeding ◽  
Surgical Resection ◽  
Rare Case ◽  
Gastrointestinal Symptoms ◽  
Young Female ◽  
Major Surgery ◽  
Epithelial Tumour ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma

Brunner’s gland hamartoma (BGH) is a rare sub-epithelial tumour of the duodenum, which may cause haemorrhagic or obstructive gastrointestinal symptoms. Their accurate histological diagnosis often remains elusive before resection. Although endoscopic ultrasonography (EUS) is considered an excellent modality to study lesions within the gastrointestinal wall, only a few reports have described endosonographic characteristics of BGHs. A reliable pre-resection diagnosis with EUS may not only allay fear of malignancy but may as well avert a major surgery for the patients. In this report, we present a rare case of a large BGH in a young female who presented with acute gastrointestinal bleeding. Here, the endosonographic features assuaged the concern for malignancy while aiding in complete and uneventful surgical resection of the tumour via a submucosal plane.

scholarly journals Giant Brunner’s Gland Hamartoma of the Duodenal Bulb Presenting with Upper Gastrointestinal Bleeding and Obstruction

2016 ◽  
Vol 49 (6) ◽  
pp. 570-574 ◽  
Author(s):  
Ju Hyoung Lee ◽  
Kyeong Min Jo ◽  
Tae Oh Kim ◽  
Jong Ha Park ◽  
Seung Hyun Park ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Duodenal Bulb ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma ◽  
Upper Gastrointestinal

Brunner’s Gland Hyperplasia – a Rare Cause of Gastrointestinal Bleeding

2018 ◽  
Vol 27 (1) ◽  
pp. 9-9
Author(s):  
Ion Bancila ◽  
Gabriel Becheanu ◽  
Mona Dumbrava ◽  
Roxana Costache ◽  
Cristian Gheorghe
Keyword(s):  
Gastrointestinal Bleeding ◽  
Brunner’S Gland ◽  
Brunner's Gland

.

scholarly journals Acute Pancreatitis and Upper Gastrointestinal Bleeding as Presenting Symptoms of a Duodenal Brunner’s Gland Hamartoma

2006 ◽  
Vol 20 (8) ◽  
pp. 541-542 ◽  
Author(s):  
Edy Stermer ◽  
Nizar Elias ◽  
Dean Keren ◽  
Tova Rainis ◽  
Omer Goldstein ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
English Literature ◽  
Presenting Symptoms ◽  
Acute Upper Gastrointestinal Bleeding ◽  
Brunner’S Gland ◽  
Brunner's Gland ◽  
Brunner’S Gland Hamartoma ◽  
Upper Gastrointestinal

Brunner’s gland hamartomas are rare, benign small bowel tumours. There were fewer than 150 cases reported in the English literature until the end of the last century. These hamartomas may be discovered incidentally during an upper gastrointestinal tract endoscopy. Otherwise, they may be diagnosed in patients presenting with acute upper gastrointestinal bleeding, anemia or symptoms of intestinal obstruction. The case of a young woman admitted for acute upper gastrointestinal bleeding along with acute pancreatitis is presented. The investigation revealed a giant Brunner’s gland hamartoma in the second part of the duodenum. After total endoscopic resection of the tumour, the patient has remained completely asymptomatic for a follow-up period of seven months.

scholarly journals Brunner’s Gland Hamartomas: Two Cases of This (Sometimes) Distinctive Lesion

2020 ◽  
Author(s):  
Allison Bush ◽  
Jonathan Francis ◽  
Jeffrey Laczek
Keyword(s):  
Surgical Resection ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Clinical Presentations ◽  
Brunner’S Gland ◽  
Brunner's Gland

Abstract Brunner’s gland hamartomas (BGHs) are rare, benign, primary duodenal tumors. The clinical presentations can vary, and confirming a diagnosis can be challenging because of the submucosal nature of the lesions. We report two cases of BGHs with different clinical presentations. The diagnoses were not determined initially, despite utilizing endoscopy, mucosal biopsies, endoscopic ultrasound, and, in one case, fine-needle aspiration. Confirmation of BGHs was subsequently made following endoscopic or surgical resection.

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