Low doses of vanadyl sulfate protect rats from lipid peroxidation and hypertriglyceridemic effects of fructose-enriched diet

2006 ◽  
Vol 14 (3) ◽  
pp. 134-137 ◽  
Author(s):  
Mehdi Harati M. ◽  
Mohsen Ani M.
Keyword(s):  
Lipid Peroxidation ◽  
Vanadyl Sulfate ◽  
Low Doses

scholarly journals Influence of very low dietary intake of marine oil on some fuctional aspects of immune cells in healthy elderly people

2003 ◽  
Vol 89 (4) ◽  
pp. 523-531 ◽  
Author(s):  
Shaliha Bechoua ◽  
Madeleine Dubois ◽  
Evelyne Véricel ◽  
Paul Chapuy ◽  
Michel Lagarde ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Fatty Acids ◽  
Placebo Group ◽  
Elderly People ◽  
Cyclic Nucleotide ◽  
Elderly Subjects ◽  
Low Doses ◽  
Marine Oil ◽  
Healthy Elderly ◽  
Healthy Elderly People

Ageing is a multifactorial process involving decreased antioxidant defences and immune functions. n-3 Polyunsaturated fatty acids have been associated with human health benefits, especially against inflammatory and autoimmune diseases. However, their immunomodulatory effects were usually observed with high dosages (>2 g/d) known to increase lipid peroxidation. In contrast, very low doses, that may prevent lipid peroxidation, might affect the immune system differently. To study the latter hypothesis further, we investigated whether the supplementation of healthy elderly people with very low doses of marine oil (MO), a docosahexaenoate (DHA)- and eicosapentaenoate (EPA)-rich triacylglycerol, was able to affect lymphocyte proliferation and biochemical markers known to be altered with age. In a randomized, double-blind design, twenty healthy elderly subjects were assigned to a placebo group (600 mg sunflower oil/d) or to a group consuming 600 mg MO/d providing 150 mg DHA + 30 mg (EPA) for 6 weeks. At day 42, the proliferative responses of lymphocytes to several mitogens were significantly (P<0·01) decreased in the MO group compared with control values. This was accompanied by a slight lowering of their cytosolic cyclic nucleotide phosphodiesterase (PDE) activity, a marked and significant (P<0·05) increase of their particulate PDE activity (+56–57 %) and a slight but significant (P<0·05) increase in cyclic nucleotide intracellular levels. At the same time, the glutathione peroxidase activity was markedly and significantly (P<0·01) depressed in the MO group. None of these modifications could be seen in the placebo group. Collectively, these results demonstrate that even very low doses of n-3 fatty acids are sufficient to affect the immune responses of elderly subjects.

scholarly journals Supplementation With Low Doses of Vitamin E Protects LDL From Lipid Peroxidation in Men and Women

1995 ◽  
Vol 15 (3) ◽  
pp. 325-333 ◽  
Author(s):  
Hans M.G. Princen ◽  
Wim van Duyvenvoorde ◽  
Rien Buytenhek ◽  
Arnoud van der Laarse ◽  
Geert van Poppel ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Vitamin E ◽  
Low Doses ◽  
Men And Women

Oxidative stress and lipid peroxidation in the earthworm Eisenia fetida induced by low doses of fomesafen

2012 ◽  
Vol 20 (1) ◽  
pp. 201-208 ◽  
Author(s):  
Qingming Zhang ◽  
Lusheng Zhu ◽  
Jun Wang ◽  
Hui Xie ◽  
Jinhua Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Eisenia Fetida ◽  
Low Doses

Supplementation with low doses of vitamin E protects low density lipoprotein from lipid peroxidation in men and women

1995 ◽  
Vol 115 ◽  
pp. S42
Author(s):  
H.M.G. Princen ◽  
W. van Duyvenvoorde ◽  
R. Buytenhek ◽  
A. van der Laarse ◽  
G. van Poppel ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Vitamin E ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Low Doses ◽  
Men And Women
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