Interventional Bronchoscopy for the Treatment of Malignant Central Airway Stenosis: An Expert Recommendation for China

Respiration ◽  
2019 ◽  
Vol 97 (5) ◽  
pp. 484-494
Author(s):  
Faguang Jin ◽  
Qiang Li ◽  
Shiyue Li ◽  
Hongwu Wang ◽  
Chong Bai ◽  
...  
Keyword(s):  
Interventional Bronchoscopy ◽  
Airway Stenosis ◽  
Expert Recommendation ◽  
Central Airway

scholarly journals Long-term prognostic factors of clinical success after interventional bronchoscopy in patients with scarring central airway stenosis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kunyan Sun ◽  
Hong Zhang ◽  
Wei Zhang ◽  
Yuan Cheng ◽  
Guangfa Wang
Keyword(s):  
Logistic Regression ◽  
Prognostic Factors ◽  
Clinical Success ◽  
Current Smoker ◽  
Subglottic Stenosis ◽  
Multivariate Logistic Regression ◽  
Interventional Bronchoscopy ◽  
Airway Stenosis ◽  
Central Airway

Abstract Background Scarring central airway stenosis (SCAS) is a potentially life-threatening condition with debilitating symptoms. Interventional bronchoscopy is increasingly used to relieve symptoms in patients with SCAS, but recurrent stenosis is frequently observed. Little data exist on the long-term prognosis of interventional bronchoscopy for SCAS. We aimed to assess the prognostic factors of bronchoscopic interventions in patients with SCAS to optimize treatment. Methods This was a retrospective study that enrolled 119 consecutive patients with SCAS from January 2010 to April 2019 at our institution. Long-term clinical success was defined as airway stenosis < 50%, no limitation of physical activity, and a stable condition for > 12 months after the last interventional procedure. We compared patients’ demographics, airway stenosis characteristics, and interventional procedures between the successful and unsuccessful groups, and identified significant predictors of long-term outcome with univariate and multivariate logistic regression. Results A total of 119 patients with 577 therapeutic bronchoscopies were included. Seventy-five (63%) patients were considered to have long-term clinical success. Older age, male gender, smoking, elevated C-reactive protein level, subglottic stenosis, stent or T-tube implantation, previous interventional treatment, and multiple procedures per year were potentially associated with unsuccessful long-term outcomes in the univariate analysis. Current smoker status (odds ratio [OR] 5.70, 95% confidence interval [CI] 1.35–24.17, P = 0.018), subglottic stenosis (OR 4.35, 95% CI 1.31–14.46, P = 0.017), and stent implantation (OR 4.96, 95% CI 1.33–18.48, P = 0.017) were associated with decreased odds of long-term success in the multivariate logistic regression analysis. Of note, there was no significant difference in odds of success between former smokers and nonsmokers. Conclusions Current smoker status, subglottic stenosis, and stent implantation are independent factors associated with reduced long-term efficacy of interventional bronchoscopy for SCAS. Smoking cessation should be encouraged to improve the outcome of therapeutic bronchoscopy.

scholarly journals Central Airway Stenosis: Opening the Path

2020 ◽  
Vol 56 (11) ◽  
pp. 695-696
Author(s):  
Fernando Guedes ◽  
Ana Colette Maurício ◽  
António Bugalho
Keyword(s):  
Airway Stenosis ◽  
Central Airway

Endoscopic Treatment of Central Airway Stenosis: Five Years' Experience

2005 ◽  
Vol 41 (6) ◽  
pp. 322-327 ◽  
Author(s):  
A. Cosano Povedano ◽  
L. Muñoz Cabrera ◽  
F.J. Cosano Povedano ◽  
J. Rubio Sánchez ◽  
N. Pascual Martínez ◽  
...  
Keyword(s):  
Endoscopic Treatment ◽  
Airway Stenosis ◽  
Central Airway

Contributions of Airway Stent for Long-term Outcome in Patients With Malignant Central Airway Stenosis or Obstruction

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Akira Iyoda ◽  
Yoko Azuma ◽  
Atsushi Sano ◽  
Takashi Sakai ◽  
Satoshi Koezuka ◽  
...  
Keyword(s):  
Stenosis Or Obstruction ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Airway Stenosis ◽  
Airway Stent ◽  
Central Airway

scholarly journals Diagnostic Value of Virtual Bronchoscopic Navigation in the Bronchial Tuberculosis Induced Central Airway Stenosis

2020 ◽  
Vol 9 (1) ◽  
pp. 165-174 ◽  
Author(s):  
Li-Ping Cheng ◽  
Ye Gu ◽  
Xu-Wei Gui ◽  
Yong Fang ◽  
Hao Wang ◽  
...  
Keyword(s):  
Diagnostic Value ◽  
Airway Stenosis ◽  
Central Airway
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