The Clinical Relevance of Natural Rubber Latex-Specific IgE in Patients Sensitized to Timothy Grass Pollen

2019 ◽  
Vol 178 (4) ◽  
pp. 345-354 ◽  
Author(s):  
Sandra Louise Brandi ◽  
Lars K. Poulsen ◽  
Lene Heise  Garvey
Allergy ◽  
1998 ◽  
Vol 53 (1) ◽  
pp. 59-67 ◽  
Author(s):  
T. Palosuo ◽  
S. Mäkinen-Kiljunen ◽  
H. Alenius ◽  
T. Reunala ◽  
E. Yip ◽  
...  

Author(s):  
Raymond E. Biagini ◽  
Barbara A. Mackenzie ◽  
Toni A. Bledsoe ◽  
Daniel M. Lewis ◽  
Lynne M. Pinkerton

2002 ◽  
Vol 7 (5) ◽  
pp. 1-3
Author(s):  
Jon Musmand ◽  
Christopher R. Brigham

Abstract Natural rubber latex (NRL) allergy is discussed in the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), Fifth Edition, in Section 8.5, Natural Rubber Latex Allergy, and refers to an IgE-mediated immediate hypersensitivity reaction to one or more protein allergens in latex devices, especially gloves. Among health care workers, NRL allergy is the most common cause of occupationally induced rhinoconjunctivitis and asthma, and clinical manifestations range from dermatitis and contact urticaria, allergic rhinoconjunctivitis, and asthma, to anaphylaxis. Evaluating physicians must be cognizant that a suggestive clinical history is necessary but not sufficient to diagnose NRL allergy, and FDA-approved NRL-specific IgE serum tests may have sensitivity as low as 75% and up to 27% false-positive results. No FDA-approved skin test reagent is available for testing. In evaluating impairment due to NRL allergy, evaluators should determine if the individual's problem can be resolved by avoidance of wearing latex gloves. Most patients who have asthma or air passage disruption impairment due to NRL have problems with bronchospasm only when they are exposed, and these patients may not necessarily have any ratable impairment due to NRL (but individuals who have atopic dermatitis may have ongoing symptoms due to pre-existing allergic rhinitis). Efforts to decrease the incidence of NRL allergy have been encouraging, and some patients diagnosed with NRL allergy may return to work in a latex-safe environment.


1995 ◽  
Vol 109 (11) ◽  
pp. 1094-1096 ◽  
Author(s):  
V. Kujala ◽  
T. Pirilä ◽  
A. Niinimäki ◽  
K. Reijula

AbstractA case of occupational rhinitis in association with natural rubber latex hypersensitivity is presented. In the nasal provocation test for natural rubber latex glove powder the nurse experienced rhinorrhoea. A significant increase in the amount of nasal secretion and mucosal oedema could be detected. The patient also showed a positive skin prick test to natural rubber latex allergens, and an elevated natural rubber specific IgE level in her serum. This, to our knowledge, has not been previously reported in the literature.


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