scholarly journals Advanced Renal Cell Cancer and Low-Dose Palliative Radiation Treatment: A Case of a Substantial and Sustained Treatment Response

2018 ◽  
Vol 11 (3) ◽  
pp. 756-762 ◽  
Author(s):  
Kirsten van Gysen ◽  
Andrew Kneebone ◽  
Thomas Eade ◽  
Alexander Guminski ◽  
George Hruby
Keyword(s):  
Cell Carcinoma ◽  
Renal Cell ◽  
Low Dose ◽  
Radiation Treatment ◽  
Cell Cancer ◽  
Palliative Radiation ◽  
Improved Outcomes ◽  
Palliative Radiation Therapy ◽  
Systemic Agents ◽  
Advanced Renal Cell Cancer

Clear cell carcinoma is the most common form of renal cell carcinoma (RCC). Metastatic RCC is poorly responsive to treatment and has a bleak prognosis. Newer systemic agents have improved outcomes. Furthermore, their interaction with radiation treatment (RT) may provide further therapeutic options. RCC is considered to be radioresistant, however we report the case of a patient with progression on targeted therapy and immunotherapy who achieved a substantial and sustained local, and possibly abscopal, response to low dose palliative radiation therapy.

scholarly journals Interim Results of a Phase II Study of Sunitinib and Low Dose Metronomic Cyclophosphamide in Advanced Renal Cell Cancer

2012 ◽  
Vol 23 ◽  
pp. ix273-ix274
Author(s):  
M.A. Khattak ◽  
K. Edmonds ◽  
K. Khabra ◽  
A. Sohaib ◽  
K. Pennert ◽  
...  
Keyword(s):  
Phase Ii ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Low Dose ◽  
Phase Ii Study ◽  
Cell Cancer ◽  
Metronomic Cyclophosphamide ◽  
Advanced Renal Cell Cancer

Nivolumab Versus Everolimus in Advanced Renal Cell Carcinoma

2021 ◽  
pp. 123-128
Author(s):  
Christopher Weight
Keyword(s):  
Renal Cell Carcinoma ◽  
Overall Survival ◽  
Adverse Events ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Antiangiogenic Therapy ◽  
Cell Cancer ◽  
Immune Checkpoint Blockade ◽  
New Class ◽  
Advanced Renal Cell Cancer

This chapter summarizes the findings of the landmark CheckMate 025 trial for the new class of drugs of immune checkpoint blockade in advanced renal cell cancer. The trial randomized patients with metastatic renal cell carcinoma who had failed antiangiogenic therapy to systemic therapy with nivolumab versus everolimus and found improved overall survival and fewer treatment-related adverse events in the nivolumab arm.

Subcutaneous IL-2 and Low-Dose IFN-α2a in the Treatment of Unselected Patients with Advanced Renal Cell Cancer

1994 ◽  
Vol 17 (3) ◽  
pp. 263-269 ◽  
Author(s):  
I. Funke ◽  
E. Späth-Schwalbe ◽  
G. Stohlmann ◽  
O. Prümmer ◽  
H. Gallati ◽  
...  
Keyword(s):  
Renal Cell Cancer ◽  
Renal Cell ◽  
Low Dose ◽  
Cell Cancer ◽  
Advanced Renal Cell Cancer

Phase II Trial of Recombinant Alpha-2b-Interferon and Low-Dose Cyclophosphamide in Advanced Melanoma and Renal Cell Carcinoma

1988 ◽  
Vol 11 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Scott Wadler ◽  
Avi I. Einzig ◽  
Janice P. Dutcher ◽  
Niculae Ciobanu ◽  
Leon Landau ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Phase Ii ◽  
Renal Cell ◽  
Low Dose ◽  
Phase Ii Trial ◽  
Advanced Melanoma

Phase II Trial of Low Dose γ -Interferon in Metastatic Renal Cell Carcinoma

1994 ◽  
Vol 152 (3) ◽  
pp. 841-845 ◽  
Author(s):  
Julie A. Ellerhorst ◽  
Robert G. Kilbourn ◽  
Robert J. Amato ◽  
Alexander A. Zukiwski ◽  
Elaine Jones ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Phase Ii ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Low Dose ◽  
Phase Ii Trial ◽  
Γ Interferon

scholarly journals Emerging role of tyrosine kinase inhibitors in the treatment of advanced renal cell cancer: a review

2006 ◽  
Vol 17 (8) ◽  
pp. 1185-1196 ◽  
Author(s):  
P. Schöffski ◽  
H. Dumez ◽  
P. Clement ◽  
A. Hoeben ◽  
H. Prenen ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Kinase Inhibitors ◽  
Cell Cancer ◽  
Advanced Renal Cell Cancer

Immunologic study of human recombinant interleukin-2 (low dose) in patients with advanced renal cell carcinoma

Urology ◽  
1989 ◽  
Vol 33 (3) ◽  
pp. 219-225 ◽  
Author(s):  
Ken Marumo ◽  
Junro Muraki ◽  
Munehisa Ueno ◽  
Masaaki Tachibana ◽  
Nobuhiro Deguchi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Low Dose ◽  
Interleukin 2 ◽  
Advanced Renal Cell Carcinoma ◽  
Recombinant Interleukin 2
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