TOLERABILITY AND TUMOR RESPONSE OF A NOVEL LOW-DOSE PALLIATIVE RADIATION THERAPY PROTOCOL IN DOGS WITH TRANSITIONAL CELL CARCINOMA OF THE BLADDER AND URETHRA

2016 ◽  
Vol 57 (3) ◽  
pp. 341-351 ◽  
Author(s):  
Kevin Choy ◽  
Janean Fidel
Keyword(s):  
Radiation Therapy ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Low Dose ◽  
Tumor Response ◽  
Transitional Cell ◽  
Palliative Radiation ◽  
Palliative Radiation Therapy ◽  
Carcinoma Of The Bladder ◽  
Therapy Protocol

Piroxicam, Mitoxantrone, and Coarse Fraction Radiotherapy for the Treatment of Transitional Cell Carcinoma of the Bladder in 10 Dogs: A Pilot Study

2004 ◽  
Vol 40 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Valerie J. Poirier ◽  
Lisa J. Forrest ◽  
William M. Adams ◽  
David M. Vail
Keyword(s):  
Radiation Therapy ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Clinical Signs ◽  
Treatment Protocol ◽  
Coarse Fraction ◽  
Survival Duration ◽  
Carcinoma Of The Bladder ◽  
Therapy Protocol

Ten dogs with transitional cell carcinoma (TCC) of the bladder were treated with a combination of once-weekly coarse fraction radiation therapy (six weekly fractions of 5.75 Gray [Gy]), mitoxantrone chemotherapy, and piroxicam. All dogs completed the radiation therapy protocol, and only minimal side effects were observed. Only two (22%) dogs achieved a measurable partial response; however, 90% of the dogs had amelioration of their urinary clinical signs. The median survival time for all dogs was 326 days. While this treatment protocol was well tolerated, the response rate and overall survival duration was not superior to reports using mitoxantrone and piroxicam without radiation therapy in dogs with TCC.

969: Intravesical Antisense G3139 Efficacy in Transitional Cell Carcinoma of the Bladder

2004 ◽  
Vol 171 (4S) ◽  
pp. 257-257
Author(s):  
Sam B. Gray ◽  
Brian J. Duggan ◽  
Perry Maxwell ◽  
Ken Arthur ◽  
Neil Anderson ◽  
...  
Keyword(s):  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Carcinoma Of The Bladder
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