Psychometric Validation of the Czech Version of the Quality of Life – Alzheimer’s Disease Scale in Patients with Early-Stage Dementia

2018 ◽  
Vol 46 (1-2) ◽  
pp. 109-118 ◽  
Author(s):  
Helena Kisvetrová ◽  
David Školoudík ◽  
Roman Herzig ◽  
Martin Vališ ◽  
Božena Jurašková ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Convergent Validity ◽  
Early Stage ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Psychometric Validation ◽  
Physical And Mental Health

Background/Aims: The aim of this study was to perform a psychometric validation of the Czech version of the Quality of Life – Alzheimer’s Disease scale (QoL-AD) for patients with early-stage dementia. Methods: The sample included 212 patient-proxy pairs. For convergent validity, the Czech version of the Bristol Activities of Daily Living Scale (BADLS-CZ), the Short Physical Performance Battery (SPPB), and the Geriatric Depression Scale (GDS) were used. Results: The reliability of the QoL-AD for patients and caregivers was good (Cronbach’s α = 0.85, ICC = 0.25–0.54). A positive correlation existed between the QoL-AD and the SPPB, and negative correlations existed between the QoL-AD and the BADLS-CZ as well as between the QoL-AD and the GDS. Factor analysis resulted in a three-factor solution (physical and mental health, family life, and social security). Conclusion: The Czech version of the QoL-AD has good psychometric properties in compliance with international recommendations.

scholarly journals An Experimental Pilot Study of Global Postural Reeducation Concerning the Cognitive Approach of Patients With Alzheimer’s Disease

2019 ◽  
Vol 35 ◽  
pp. 153331751986782 ◽  
Author(s):  
Jasemin Todri ◽  
Orges Lena ◽  
José Luis Martínez Gil
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Repeated Measures ◽  
Therapeutic Option ◽  
Depression Scale ◽  
Control Group ◽  
Cognitive Approach ◽  
Positive Effects

Background: Several recent studies have examined the positive effects of physical exercise and equilibrium on individuals with neurodegenerative diseases. Objectives: In this sense, this study based on an experimental design, tested whether global postural reeducation (GPR) can affect equilibrium and cognition, life quality, and psychological symptoms of patients with Alzheimer’s disease (AD). Methods: One hundred thirty-five participants with mild and moderate AD diagnosis were assigned to 2 groups: experimental group (EG, n = 90) and control group (CG, n = 45). The GPR therapy was implemented in the EG for 6 months, while both groups underwent neuropsychological assessments prior and after the 6-month period. Results: According to the repeated measures of analysis of variance, significant differences between groups were found at the 6-month follow-up period, in benefit of the EG such as Mini-Mental State Examination ( P = .000), Geriatric Depression Scale ( P = .000), Neuropsychiatric Inventory ( P = .000), quality of life in AD/patient ( P = .000), quality of life in AD/caregivers ( P = .000), Barthel index ( P = .000), and Tinetti Scale ( P = .000), while the CG showed a low performance in the neuropsychological tests. Conclusions: We suggest that GPR is a therapeutic option, which can improve the psychological, physical, and cognitive aspects of patients with AD.

scholarly journals Cognitive rehabilitation for early stage Alzheimer’s disease: a pilot study with an Irish population

2017 ◽  
Vol 36 (2) ◽  
pp. 105-119 ◽  
Author(s):  
M. E. Kelly ◽  
B. A. Lawlor ◽  
R. F. Coen ◽  
I. H. Robertson ◽  
S. Brennan
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Self Efficacy ◽  
Cognitive Rehabilitation ◽  
Early Stage ◽  
Single Subject ◽  
Everyday Functioning ◽  
Post Test

ObjectivesResearch shows that cognitive rehabilitation (CR) has the potential to improve goal performance and enhance well-being for people with early stage Alzheimer’s disease (AD). This single subject, multiple baseline design (MBD) research investigated the clinical efficacy of an 8-week individualised CR intervention for individuals with early stage AD.MethodsThree participants with early stage AD were recruited to take part in the study. The intervention consisted of eight sessions of 60–90 minutes of CR. Outcomes included goal performance and satisfaction, quality of life, cognitive and everyday functioning, mood, and memory self-efficacy for participants with AD; and carer burden, general mental health, quality of life, and mood of carers.ResultsVisual analysis of MBD data demonstrated a functional relationship between CR and improvements in participants’ goal performance. Subjective ratings of goal performance and satisfaction increased from baseline to post-test for three participants and were maintained at follow-up for two. Baseline to post-test quality of life scores improved for three participants, whereas cognitive function and memory self-efficacy scores improved for two.ConclusionsOur findings demonstrate that CR can improve goal performance, and is a socially acceptable intervention that can be implemented by practitioners with assistance from carers between sessions. This study represents one of the promising first step towards filling a practice gap in this area. Further research and randomised-controlled trials are required.

scholarly journals Caregiver rating bias in mild cognitive impairment and mild Alzheimer's disease: impact of caregiver burden and depression on dyadic rating discrepancy across domains

2013 ◽  
Vol 25 (8) ◽  
pp. 1345-1355 ◽  
Author(s):  
Livia Pfeifer ◽  
Reinhard Drobetz ◽  
Sonja Fankhauser ◽  
Moyra E. Mortby ◽  
Andreas Maercker ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Caregiver Burden ◽  
Depression Scale ◽  
Caregiver Rating ◽  
Rating Bias

ABSTRACTBackground: Caregivers of individuals with dementia are biased in their rating of mental health measures of the care receiver. This study examines caregiver burden and depression as predictors of this bias for mild cognitive impairment and mild Alzheimer's disease in different domains.Methods: The sample consisted of 202 persons: 60 with mild cognitive impairment, 41 with mild Alzheimer's disease, and 101 caregivers. Discrepancy scores were calculated by subtracting the mean caregiver score from the respective mean patient score on the following assessment instruments: the Geriatric Depression Scale, Apathy Evaluation Scale, Bayer-Activities of Daily Living Scale, and Quality of Life-AD scale. Caregiver burden and depression were assessed by the Zarit Burden Interview and the Center for Epidemiologic Studies Depression Scale.Results: Intraclass correlation coefficients were low for apathy (0.38), daily functioning (0.38), and quality of life (0.30) and moderate for depression (0.49). These domains showed negative rating discrepancies, which indicates caregiver rating bias for all four domains. Regression analyses revealed that caregiver burden significantly contributed to explaining these discrepancies in the domains apathy, daily functioning, and quality of life.Conclusion: Caregiver rating bias can be attributed to caregiver burden. When caregiver burden is present, data based on caregiver ratings should therefore be interpreted with caution.

scholarly journals Quality of life and Alzheimer's disease: Influence of participation at a rehabilitation center

2009 ◽  
Vol 3 (3) ◽  
pp. 241-247 ◽  
Author(s):  
Fernanda Machado ◽  
Paula V. Nunes ◽  
Luciane F. Viola ◽  
Franklin S. Santos ◽  
Orestes V. Forlenza ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Positive Impact ◽  
Depression Scale ◽  
Therapeutic Interventions ◽  
Control Group ◽  
Functional Rehabilitation ◽  
Open Question

Abstract Quality of life is seldom explored in evaluations of therapeutic interventions in Alzheimer's disease. Objective: To verify whether participation in a cognitive and functional rehabilitation program improves quality of life (QOL) among Alzheimer's disease (AD) patients. Methods: 19 AD patients participated in this study, 12 of whom attended 24 multi-professional intervention sessions - the experimental group - whereas the remaining 7 comprised the control group. The following tools were used to assess changes: a) Mini-Mental State Examination (MMSE); b) Geriatric Depression Scale (GDS); c) Quality of Life in AD evaluation scale (QOL-AD); d) Open question on QOL. Results: Participation had no positive impact on quantitative clinical variables (MMSE, GDS, QOL-AD). The answers to the open question, examined using the Collective Subject Discourse (CSD) method, suggested that QOL improved after the intervention. Conclusion: Combining pharmacological treatment with psychosocial intervention may prove to be an effective strategy to enhance the QOL of AD patients.

A mentally stimulating activities program for the treatment of neuropsychiatric symptoms in Alzheimer’s disease

2019 ◽  
Vol 18 (4) ◽  
pp. 27-37
Author(s):  
Angie L. Sardina, PhD ◽  
Suzanne Fitzsimmons, MSN, ARNP, GNP ◽  
Catherine M. Hoyt, BA ◽  
Linda L. Buettner, PhD
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Support Group ◽  
Repeated Measures ◽  
Early Stage ◽  
Neuropsychiatric Symptoms ◽  
Cognitive Status ◽  
Control Group

This study evaluated whether a mentally stimulating activities (MSA) program reduced neuropsychiatric symptoms and improved cognitive status and quality of life, as compared to a support group for persons in the early stage of Alzheimer’s disease (AD). This randomized controlled trial included 81 adults (aged 55+), who were randomly assigned to the MSA group (treatment) or a social support group (control). A repeated measures multivariate analysis of variance (MANOVA) identified that MSA participants significantly reduced apathy (p 0.001) and depressive symptoms (p 0.001), as well as improved cognitive status (p 0.001) and quality of life (p 0.001) as compared to the control group. A structured classroom-style MSA program may be a viable and therapeutic intervention to alleviate neuropsychiatric symptoms, and improve cognitive status and quality of life in early-stage AD.

The ICT4LIFE Project–Design and development of a new information technology platform for patients with Alzheimer's disease

2017 ◽  
Vol 41 (S1) ◽  
pp. S545-S546
Author(s):  
P. Osvath ◽  
V. Voros ◽  
A. Kovacs ◽  
I. Greges ◽  
S. Fekete ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Integrated Care ◽  
Brain Research ◽  
Early Stage ◽  
Real Life ◽  
User Friendly

AimWith an increasingly growing population in Europe, cognitive impairment is a major social and health issue. According to the World Alzheimer Report (WHO, 2014), dementia, including Alzheimer's disease is one of the biggest global public health challenges our generation is facing. There are many efforts at European level to promote active and healthy ageing. This three-year project has the ambition to provide new services for integrated care with breakthrough research and radical innovation by employing user-friendly Information and Communication Technology (ICT) tools, ultimately increasing patients’ quality-of-life and autonomy at home.MethodsICT4Life proposes an innovative platform for integrated care by the use of sensor-based analytics for human behaviour. Novel ICT services are used to determine the relation between cognitive decline, related psychopathological symptoms and the quality-of-life of the patients, and to assess how these affect patients’ and caregivers’ daily living. ICT4Life platform uses advanced sensor-based analytics; to maximize elderly empowerment and self-care abilities thanks to a properly designed and reconfigurable recommendation system that will be able to exploit user-generated data; and to improve decision-making processes in care professionals’ daily activities. All solutions are developed following a user-centred methodology and tested in real-life scenarios.ResultsThe study design and the preliminary results of the ICT4Life project are presented on the poster.ConclusionICT4Life programme develops a solution for individuals with early stage cognitive impairment that will permit doctors and caregivers to extract useful information about patients, while contributing in a user-friendly way to extending their independence.Disclosure of interestCOI: This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement N° 690090. Tamas Tenyi and Sandor Fekete are supported by the National Brain Research Program Grant N° NAP KTIA NAP-A-II/12.

scholarly journals Relationship between radiologic gravity and predicting instruments of physical and mental health in elderly with knee osteoarthritis

2020 ◽  
Author(s):  
Isadora Ribeiro ◽  
Arlete Maria Valente Coimbra ◽  
Beatriz Lavras Costallat ◽  
Ibsen Bellini Coimbra
Keyword(s):  
Quality Of Life ◽  
Knee Osteoarthritis ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Womac Score ◽  
Depression Symptoms ◽  
Physical And Mental Health ◽  
Timed Up And Go ◽  
Risk Of Fall

Abstract BACKGROUND: This study aimed to investigate the relationship between radiologic severity by the grades of the Kellgren-Lawrence scale (K&Ls) independently and in two groups (grades "0 and 1" and "2 to 4") and instruments that assess depression symptoms, cognitive loss, risk of fall and quality of life related to knee osteoarthritis. METHODS: The analyzed materials were derived from a database and collected between 2013-2014 in Amparo (São Paulo, Brazil). 181 elderly with knee osteoarthritis who had a radiologic exam were evaluated for depressive symptoms, cognitive loss, quality of life and risk of fall by: Geriatric Depression Scale (GDS), Mini Mental State Examination (MMSE), WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index), Timed Up and Go test (TUG) and Berg Balance Scale (BBS). To statistical analyses was used Fisher's exact test, Mann-Whitney test, Kruskal-Wallis test and Spearman's coefficient. RESULTS: There was no significant relationship between the instruments investigated and the grades assessed individually. However, when assessed by groups, grades “2 to 4” had the worst WOMAC score, the highest frequency and the worst risk of fall in the BBS, but not in the TUG. For GDS and MMSE, no significant relationships were found. In addition, K&Ls was correlated with the WOMAC socre, with no differences between their domains. CONCLUSION: Only when evaluated in groups, the radiological scores of the Kellgren-Lawrence scale pointed to a worse status in the WOMAC and BBS and the WOMAC score accompanies the increase in the radiological grade.

Validación de la escala Quality of Life in Alzheimer’s Disease (QOL-AD) en pacientes mexicanos con demencia tipo Alzheimer, vascular y mixta

2010 ◽  
Vol 51 (02) ◽  
pp. 72 ◽  
Author(s):  
Oscar Rosas Carrasco ◽  
Laura del Pilar Torres Arreola ◽  
María de Guadalupe Guerra Silla ◽  
Sara Torres Castro ◽  
Luis Miguel Gutiérrez Robledo
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease

Assessing Alzheimer's disease patients' quality of life: Discrepancies between patient and caregiver perspectives

2015 ◽  
Vol 12 (4) ◽  
pp. 427-437 ◽  
Author(s):  
Sandrine Andrieu ◽  
Nicola Coley ◽  
Yves Rolland ◽  
Christelle Cantet ◽  
Catherine Arnaud ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease
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