scholarly journals Characterization of Pancreatic Tumors with Quantitative Perfusion Analysis in Contrast-Enhanced Harmonic Endoscopic Ultrasonography

Oncology ◽  
2017 ◽  
Vol 93 (1) ◽  
pp. 55-60 ◽  
Author(s):  
Shunsuke Omoto ◽  
Mamoru Takenaka ◽  
Masayuki Kitano ◽  
Takeshi Miyata ◽  
Ken Kamata ◽  
...  
2012 ◽  
Vol 107 (2) ◽  
pp. 303-310 ◽  
Author(s):  
Masayuki Kitano ◽  
Masatoshi Kudo ◽  
Kenji Yamao ◽  
Tadayuki Takagi ◽  
Hiroki Sakamoto ◽  
...  

2010 ◽  
Vol 71 (5) ◽  
pp. AB281 ◽  
Author(s):  
Abdenor Badaoui ◽  
Ivan Borbath ◽  
Tarik Aouattah ◽  
Cedric Gillain ◽  
Thierry De Ronde ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Yasunobu Yamashita ◽  
Jun Kato ◽  
Kazuki Ueda ◽  
Yasushi Nakamura ◽  
Yuki Kawaji ◽  
...  

Objectives. To investigate the usefulness of contrast-enhanced endoscopic ultrasonography (CE-EUS) for histological differentiation of pancreatic tumors.Methods. CE-EUS was performed for consecutive patients having a pancreatic solid lesion, and tumors were classified into three vascular patterns (hypervascular, isovascular, and hypovascular) at two time phases (early-phase and late-phase). Correlation between vascular patterns and histopathology of resected pancreatic cancer (PC) tissues was ascertained.Results. The final diagnoses of 147 examined tumors were PC(n=109), inflammatory mass(n=11), autoimmune pancreatitis(n=9), neuroendocrine tumor(n=8), and others(n=10). In late-phase images, 104 of 109 PCs had the hypovascular pattern, for a diagnostic sensitivity and specificity of 94% and 71%, respectively. Of 28 resected PCs, 10 had isovascular, and 18 hypovascular, patterns on the early-phase image. Early-phase isovascular PCs were more likely to be differentiated than were early-phase hypovascular PCs (6 well and 4 moderately differentiated versus 3 well, 14 moderately, and 1 poorly differentiated,P=0.028). Immunostaining revealed that hypovascular areas of early-phase images reflected heterogeneous tumor cells with fibrous tissue, necrosis, and few vessels.Conclusion. CE-EUS could be useful for distinguishing PC from other solid pancreatic lesions and for histological differentiation of PCs.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Can Xu ◽  
Zhaoshen Li ◽  
Michael Wallace

Endoscopic ultrasonography (EUS) is the most sensitive imaging method for diagnosis of pancreatic tumors. However, it still has limits in the differentiation between pancreatic cancers and inflammatory tumor-like masses. A novel technology, contrast-enhanced harmonic EUS (CH-EUS), has been developed recently. It can visualize both parenchymal perfusion and microvasculature in pancreas without Doppler-related artifacts. Therefore, it is superior to EUS and CT in detecting small pancreatic masses and differential diagnosis of pancreatic masses. CH-EUS could be used for adequate sampling of pancreatic tumors and may predict the pathological features of the pancreatic solid lesions but still cannot replace EUS-FNA now.


2012 ◽  
Vol 75 (4) ◽  
pp. AB132 ◽  
Author(s):  
Mitsuharu Fukasawa ◽  
Shinichi Takano ◽  
Makoto Kadokura ◽  
Ei Takahashi ◽  
Tadashi Sato ◽  
...  

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