Real-Time Volume Contrast Imaging in the A Plane with a Four-Dimensional Electronic Probe Facilitates the Evaluation of Fetal Extremities in Midtrimester Sonograms

2017 ◽  
Vol 43 (4) ◽  
pp. 291-296
Author(s):  
Federica Bellussi ◽  
Giuliana Simonazzi ◽  
Ginevra Salsi ◽  
Francesca Guasina ◽  
Gianluigi Pilu
Keyword(s):  
Real Time ◽  
Contrast Imaging ◽  
Electronic Probe

Real-Time Excitation-Enhanced Ultrasound Contrast Imaging

2005 ◽  
Vol 27 (2) ◽  
pp. 65-74 ◽  
Author(s):  
Flemming Forsberg ◽  
William T. Shi ◽  
Michael K. Knauer ◽  
Anne L. Hall ◽  
Chris Vecchio ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging Modality ◽  
Surrounding Tissue ◽  
Contrast Imaging ◽  
Maximum Enhancement ◽  
Ultrasound Contrast ◽  
Ultrasound Contrast Imaging ◽  
Contrast Microbubbles

A new nonlinear contrast specific imaging modality, excitation-enhanced imaging (EEI) has been implemented on commercially-available scanners for real-time imaging. This novel technique employs two acoustic fields: a low-frequency, high-intensity ultrasound field (the excitation field) to actively condition contrast microbubbles, and a second lower-intensity regular imaging field applied shortly afterwards to detect enhanced contrast scattering. A Logiq 9 scanner (GE Healthcare, Milwaukee, WI) with a 3.5C curved linear array and an AN2300 digital ultrasound engine (Analogic Corporation, Peabody, MA) with a P4-2 phased array transducer (Philips Medical Systems, Bothell, WA) were modified to perform EEI on a vector-by-vector basis in fundamental and pulse inversion harmonic grayscale modes. Ultrasound contrast microbubbles within an 8 mm vessel embedded in a tissue-mimicking flow phantom (ATS Laboratories, Bridgeport, CT) were imaged in vitro. While video intensities of scattered signals from the surrounding tissue were unchanged, video intensities of echoes from contrast bubbles within the vessel were markedly enhanced. The maximum enhancement achieved was 10.4 dB in harmonic mode (mean enhancement: 6.3 dB; p=0.0007). In conclusion, EEI may improve the sensitivity of ultrasound contrast imaging, but further work is required to assess the in vivo potential of this new technique.

scholarly journals Real-time halo correction in phase contrast imaging

2017 ◽  
Author(s):  
Mikhail E. Kandel ◽  
Michael Fanous ◽  
Catherine Best-Popescu ◽  
Gabriel Popescu
Keyword(s):  
Real Time ◽  
Phase Contrast ◽  
A Priori ◽  
Spatial Coherence ◽  
Low Frequency ◽  
Nondestructive Method ◽  
Label Free ◽  
Contrast Imaging ◽  
Tissue Slices ◽  
Time Operation

AbstractAs a label-free, nondestructive method, phase contrast is by far the most popular microscopy technique for routine inspection of cell cultures. Yet, features of interest such as extensions near cell bodies are often obscured by a glow, which came to be known as the halo. Advances in modeling image formation have shown that this artifact is due to the limited spatial coherence of the illumination. Yet, the same incoherent illumination is responsible for superior sensitivity to fine details in the phase contrast geometry. Thus, there exists a trade-off between high-detail (incoherent) and low-detail (coherent) imaging systems. In this work, we propose a method to break this dichotomy, by carefully mixing corrected low-frequency and high-frequency data in a way that eliminates the edge effect. Specifically, our technique is able to remove halo artifacts at video rates, requiring no manual interaction ora prioripoint spread function measurements. To validate our approach, we imaged standard spherical beads, sperm cells, tissue slices, and red blood cells. We demonstrate the real-time operation with a time evolution study of adherent neuron cultures whose neurites are revealed by our halo correction. We show that with our novel technique, we can quantify cell growth in large populations, without the need for thresholds and calibration.

scholarly journals Dynamics of respiratory and cardiac CSF motion revealed with real-time simultaneous multi-slice EPI velocity phase contrast imaging

NeuroImage ◽  
2015 ◽  
Vol 122 ◽  
pp. 281-287 ◽  
Author(s):  
Liyong Chen ◽  
Alexander Beckett ◽  
Ajay Verma ◽  
David A. Feinberg
Keyword(s):  
Real Time ◽  
Phase Contrast ◽  
Phase Contrast Imaging ◽  
Contrast Imaging
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