Relationship between DNA Flow Cytometric Data, Nuclear Morphometric Variables and Volume-Corrected Mitotic Index in Transitional Cell Bladder Tumors

1991 ◽  
Vol 19 (4) ◽  
pp. 327-331 ◽  
Author(s):  
M.J. (b) Eskelinen ◽  
S. (c) Nordling ◽  
P.K. (a) Lipponen
Keyword(s):  
Mitotic Index ◽  
Transitional Cell ◽  
Bladder Tumors ◽  
Flow Cytometric Data ◽  
Flow Cytometric

scholarly journals Models for the electronic processing of flow cytometric data at high particle rates

Cytometry ◽  
1992 ◽  
Vol 13 (2) ◽  
pp. 149-154 ◽  
Author(s):  
A. van Rotterdam ◽  
J. Keij ◽  
J. W. M. Visser
Keyword(s):  
Flow Cytometric Data ◽  
High Particle ◽  
Flow Cytometric ◽  
Electronic Processing

Pathologic Features of Recurrent Bladder Tumors after Upper Urinary Tract Transitional Cell Carcinoma

2008 ◽  
Vol 49 (6) ◽  
pp. 502
Author(s):  
Nam Seok Lee ◽  
Sung Dae Kim ◽  
Dong Wan Sohn ◽  
Sae Woong Kim ◽  
Yong-Hyun Cho
Keyword(s):  
Urinary Tract ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Upper Urinary Tract ◽  
Bladder Tumors ◽  
Pathologic Features

scholarly journals The Cytomegalovirus-Specific IL-21 ELISpot Correlates with Allograft Function of Kidney Transplant Recipients

2018 ◽  
Vol 19 (12) ◽  
pp. 3945 ◽  
Author(s):  
Monika Lindemann ◽  
Johannes Korth ◽  
Ming Sun ◽  
Shilei Xu ◽  
Christoph Struve ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Estimated Glomerular Filtration Rate ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Flow Cytometric Data ◽  
Flow Cytometric ◽  
Allograft Function ◽  
Ifn Γ ◽  
Cellular Immune

In kidney transplant recipients, the cytomegalovirus (CMV) is frequently causing infection/reactivation and can trigger allograft rejection. To assess the risk of reactivation, the cellular immune response against CMV is increasingly assessed by cellular in vitro methods, such as the interferon (IFN)-γ ELISpot. In the current study we compared the IFN-γ ELISpot with our newly established CMV-specific ELISpot assays determining IL-17A, IL-21, IL-22, granzyme B, and perforin and correlated the results with flow cytometric data and clinical parameters. In 77 kidney transplant recipients, the highest frequency was observed for CMV pp65-specific cells secreting IFN-γ, followed by cells secreting IL-21 (62.9 and 23.2 Δ spot forming cells/105 cells). We observed a positive correlation between the percentage of CMV-specific CD3+ CD4+ CD154+ cells and results of the CMV-specific IL-21 ELISpot (p = 0.002). Results of the CMV pp65-specific IL-21 ELISpot correlated negatively with kidney function (estimated glomerular filtration rate, p = 0.006) and were significantly higher in women (p = 0.005). IL-21, a cytokine involved in aging that is secreted by activated CD4+ T cells, may also impact on allograft function. Thus, the CMV-specific IL-21 ELISpot could become a new tool to assess if CMV seropositivity represents a hazard for the graft.

scholarly journals Evaluation of the Role of Early Second Look Cystoscopy after Complete Resection of Non-Muscle Invasive Bladder Tumors

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
K A Taema ◽  
M Shabayek ◽  
A M Tawfeek ◽  
A M Emam ◽  
M M S Khafaga
Keyword(s):  
Tnm Classification ◽  
Transitional Cell ◽  
Complete Resection ◽  
Prospective Clinical Study ◽  
Low Grade ◽  
Bladder Tumors ◽  
Primary Tumors ◽  
Multiple Tumors ◽  
Second Look ◽  
Muscle Invasive

Abstract Background most of the bladder cancers are non-muscle invasion at the time of diagnosis. Non-Muscle invasive tumors confined to the mucosa and invading the lamina propria are classified as stage Ta and T1, respectively, according to the Tumor, Node, Metastasis (TNM) classification system. Aim of the Study to determine the efficacy of early second look cystoscopy after complete resection of non-muscle invasive urinary bladder tumors and its impact on subsequent treatment policy. Patients and Methods this is a prospective clinical study that was done at Urology Department, Faculty of Medicine, Ain Shams University and Damanhur Oncology Centre. A total of 40 consecutive patients with newly diagnosed non-muscle invasive bladder cancer will be enrolled in this prospective study for second-look cystoscopy with TURBT in two to six weeks after initial TURBT and follow them up in one year. Results Single tumor was found in 22 cases (55%), while multiple tumors were recognized in 18 cases (45%) with average sizes ranging from 12mm to 70mm. Low-grade transitional cell carcinoma (TCC) was found in 26 cases (65%), whereas high-grade TCC was found in 14 cases (35%). Stage PTa tumors was found in 12 cases (30%) while 28 cases (70%) have had tumors of PT1 stage. All cases underwent an early second TURBT after (2-6) weeks which has reviled the following data. The majority of cases (28 cases) representing 70% of whole study population were free with no detection of any tumors either residual or recurrence. Residual tumors were detected in six cases (15%) all of which detected in patient with large primary tumor size exceeding 50mm or patients with multiple tumors. Whole detected residual tumors were found at edges of primary tumors ranging 2-5 mm in size which were completely resected and they were of the same stage and grade as the initial tumor. Conclusion Our findings in this study support the notion that second-look cystoscopy with or without TURBT is a prerequisite in patients with superficial bladder cancers except for patients with solitary, small low-grade pTa tumors. It is particularly highly recommended for patients with extensive and multiple tumors at the first TURBT

Cytokinetic investigation of lung tumors using the anti-bromodeoxyuridine (BUDR) monoclonal antibody method: Comparison with dna flow cytometric data

1990 ◽  
Vol 45 (6) ◽  
pp. 995-1001 ◽  
Author(s):  
Laura Teodori ◽  
Maria Luisa Trinca ◽  
Wolfgang Goehde ◽  
Jorg Hemmer ◽  
Franco Salvati ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Method Comparison ◽  
Lung Tumors ◽  
Flow Cytometric Data ◽  
Flow Cytometric ◽  
Antibody Method

scholarly journals Computational Analysis of Multiparametric Flow Cytometric Data to Dissect B Cell Subsets in Vaccine Studies

2019 ◽  
Vol 97 (3) ◽  
pp. 259-267 ◽  
Author(s):  
Simone Lucchesi ◽  
Emanuele Nolfi ◽  
Elena Pettini ◽  
Gabiria Pastore ◽  
Fabio Fiorino ◽  
...  
Keyword(s):  
B Cell ◽  
Computational Analysis ◽  
Flow Cytometric Data ◽  
Flow Cytometric ◽  
B Cell Subsets
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