Sequential Hydrolysis of Three Acyl Ester Bonds in Triolein Molecule by Human Gastric Juice Lipase

Enzyme ◽  
1983 ◽  
Vol 30 (2) ◽  
pp. 115-121 ◽  
Author(s):  
Zdzisław Szafran ◽  
Teresa Kubala ◽  
Halina Szafran ◽  
Tadeusz Popiela
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice ◽  
Hydrolysis Of

scholarly journals Hydrolysis of fat by human gastric juice

Gut ◽  
1964 ◽  
Vol 5 (5) ◽  
pp. 480-484 ◽  
Author(s):  
S. Bank ◽  
L. H. Krut ◽  
I. N. Marks ◽  
B. Bronte-Stewart ◽  
P. J. Ler. Uys
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice ◽  
Hydrolysis Of

scholarly journals Substrate and inhibitor studies with human gastric aspartic proteinases

1990 ◽  
Vol 267 (3) ◽  
pp. 665-669 ◽  
Author(s):  
A Baxter ◽  
C J Campbell ◽  
C J Grinham ◽  
R M Keane ◽  
B C Lawton ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Affinity Chromatography ◽  
Gastric Juice ◽  
Synthetic Peptide ◽  
Aspartic Proteinases ◽  
Peptide Substrates ◽  
Human Gastric Juice ◽  
Slow Moving ◽  
Hydrolysis Of ◽  
Chromatography Step

The separation of pepsin isoenzymes 1, 2, 3 and 5 (gastricsin) in human gastric juice was effected by chromatography on Mono Q ion-exchanger, and slow-moving proteinase was purified to homogeneity by using a modified procedure incorporating a novel affinity-chromatography step. The pH-activity profiles of these enzymes with mucus glycoprotein and basement-membrane substrates were determined; the profiles for pepsin 2 were noticeably different, and, in general, the pH optima for the hydrolysis of basement membrane were more acidic. Pepsin 1 expressed larger specificity constants (kcat./Km) than pepsin 3 with a series of synthetic peptide substrates, reflecting greater binding (smaller Km) by pepsin 1. Inhibitor studies at pH 1.7 and 4.5 with a series of P2-substituted lactoyl-pepstatins implied that valine at position P2 was optimal for inhibiting pepsins 1, 2 and 3 but detrimental for pepsin 5, whereas lysine at position P2 was tolerated well by pepsin 5 but not by pepsins 1, 2 and 3. The potency of lactoyl-pepstatin with lysine at position P2 did not increase as a function of pH. P2-substituted lactoyl-pepstatins failed to show any inhibitory selectivity among pepsins 1, 2 and 3.

Digestive Action of Human Gastric Juice.

1956 ◽  
Vol 92 (2) ◽  
pp. 237-240 ◽  
Author(s):  
J. F. Perry ◽  
E. G. Yonehiro ◽  
P. M. Ya ◽  
H. D. Root ◽  
O. H. Wangensteen
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice

Digestion of h-EGF, h-TGF alpha, and BPC-15 in human gastric juice

1995 ◽  
Vol 31 ◽  
pp. 70 ◽  
Author(s):  
M. Veljaca ◽  
K. Chan ◽  
A. Guglietta
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice

The Preparation of Human Gastric Juice for Dual Isotope Schilling Tests

1969 ◽  
Vol 62 (11) ◽  
pp. 1436
Author(s):  
GONZALO VUELTA ◽  
MORTON B. WEINSTEIN
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice ◽  
Dual Isotope

Effects of in-vitro neutralization on the composition of the nondialyzable components of human gastric juice

1967 ◽  
Vol 12 (4) ◽  
pp. 389-395 ◽  
Author(s):  
Jack D. Welsh ◽  
Clifford D. Wallace ◽  
Anthony Walker ◽  
Lois Russell
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice

scholarly journals THE HAEMATOPOIETIC RESPONSE TO INTRA-MUSCULAR INJECTIONS OF CONCENTRATED HUMAN GASTRIC JUICE

BMJ ◽  
1934 ◽  
Vol 1 (3812) ◽  
pp. 141-143 ◽  
Author(s):  
P. J. Fouts ◽  
O. M. Helmer ◽  
L. G. Zerfas
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice

Nondialyzable B12 binding material in human gastric juice following histamine stimulation

1964 ◽  
Vol 9 (4) ◽  
pp. 246-255 ◽  
Author(s):  
Jack D. Welsh ◽  
Joe T. Hartzog ◽  
June C. May ◽  
Lois Russell
Keyword(s):  
Gastric Juice ◽  
Human Gastric Juice ◽  
Histamine Stimulation ◽  
Binding Material
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