Effectiveness of 2 Osteopathic Treatment Approaches on Pain, Pressure-Pain Threshold, and Disease Severity in Patients with Fibromyalgia: A Randomized Controlled Trial

2017 ◽  
Vol 25 (2) ◽  
pp. 122-128 ◽  
Author(s):  
Jessica Albers ◽  
Anne Jäkel ◽  
Kai Wellmann ◽  
Ulrike von Hehn ◽  
Tobias Schmidt
Keyword(s):  
Randomized Controlled Trial ◽  
Disease Severity ◽  
Pain Threshold ◽  
Primary Outcome ◽  
Controlled Trial ◽  
Pressure Pain Threshold ◽  
Control Group ◽  
Pressure Pain ◽  
Randomized Controlled ◽  
Osteopathic Treatment

Objective: To assess the effectiveness of osteopathic intervention (OI) and general osteopathic treatment (GOT) in individuals with fibromyalgia syndrome (FMS). Methods: The trial was designed as a randomized controlled trial with 2 osteopathic interventions and 1 untreated control group. The patients in the two osteopathic groups received 10 osteopathic treatments (OI or GOT) within a time period of 12 weeks. The control group did not receive any osteopathic treatment. The primary outcome was the average pain intensity (API) assessed by visual analog scale (VAS). Secondary outcomes were the pressure-pain threshold rated by means of a tender point score, and disease severity, assessed by the Fibromyalgia Impact Questionnaire (FIQ). Results: 50 patients were randomized. The primary outcome parameter API decreased from 7.2 to 4.7 in the OI group, from 6.3 to 4.3 in the GOT group, and increased slightly in the control group from 6.2 to 6.6. There were significant differences for the change in API between the OI group and the control group (VAS: 2.9, 95% confidence interval (CI) = 1.12-4.52), and between the GOT group and the control group (VAS: 2.4, 95% CI = 0.65-4.11), but no significant differences between the OI group and the GOT group. There were no significant differences for the secondary outcome parameters between the groups. Conclusion: A series of osteopathic treatments might be beneficial for patients suffering from FMS.

Osteopathie mindert Schmerzen bei Fibromyalgie

2017 ◽  
Vol 01 (02) ◽  
pp. 62-63
Author(s):  
Jessica Albers
Keyword(s):  
Randomized Controlled Trial ◽  
Complementary Medicine ◽  
Disease Severity ◽  
Pain Threshold ◽  
Controlled Trial ◽  
Pressure Pain Threshold ◽  
Randomisierte Kontrollierte Studie ◽  
Medicine Research ◽  
Randomized Controlled ◽  
Osteopathic Treatment

ZusammenfassungRandomisierte kontrollierte Studie zur Effektivität zweier osteopathischer Behandlungsansätze für Schmerz, Druckschmerzgrenzen und Schwere der Erkrankung bei Patienten mit Fibromyalgie.[Albers J, Schmidt T, Wellmann K, Jäkel A. Effectiveness of two osteopathic treatment approaches on pain, pressure pain threshold and disease severity in patients with fibromyalgia – a randomized controlled trial. In: Complementary Medicine Research (zur Publikation angenommen)]

Autonomic function and pressure pain threshold following thoracic mobilization in asymptomatic subjects: A randomized controlled trial

2018 ◽  
Vol 22 (2) ◽  
pp. 313-320 ◽  
Author(s):  
Francisco Xavier de Araujo ◽  
Maurício Scholl Schell ◽  
Giovanni Esteves Ferreira ◽  
Mariana Della Valentina Pessoa ◽  
Luiza Raulino de Oliveira ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Pain Threshold ◽  
Autonomic Function ◽  
Controlled Trial ◽  
Pressure Pain Threshold ◽  
Pressure Pain ◽  
Randomized Controlled ◽  
Asymptomatic Subjects

Effect of long-term neck muscle training on pressure pain threshold: A randomized controlled trial

2005 ◽  
Vol 9 (6) ◽  
pp. 673-673 ◽  
Author(s):  
Jari Ylinen ◽  
Esa-Pekka Takala ◽  
Hannu Kautiainen ◽  
Matti Nykänen ◽  
Arja Häkkinen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Pain Threshold ◽  
Controlled Trial ◽  
Pressure Pain Threshold ◽  
Neck Muscle ◽  
Muscle Training ◽  
Pressure Pain ◽  
Randomized Controlled

Acupuncture-induced changes of pressure pain threshold are mediated by segmental inhibition—a randomized controlled trial

Pain ◽  
2015 ◽  
Vol 156 (11) ◽  
pp. 2245-2255 ◽  
Author(s):  
Petra I. Baeumler ◽  
Johannes Fleckenstein ◽  
Franziska Benedikt ◽  
Julia Bader ◽  
Dominik Irnich
Keyword(s):  
Randomized Controlled Trial ◽  
Pain Threshold ◽  
Controlled Trial ◽  
Pressure Pain Threshold ◽  
Pressure Pain ◽  
Randomized Controlled ◽  
Induced Changes

scholarly journals A randomized controlled trial on a self-guided Internet-based intervention for gambling problems

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lara Bücker ◽  
Josefine Gehlenborg ◽  
Steffen Moritz ◽  
Stefan Westermann
Keyword(s):  
Randomized Controlled Trial ◽  
Depressive Symptoms ◽  
Primary Outcome ◽  
Controlled Trial ◽  
Group Differences ◽  
Control Group ◽  
Gambling Problems ◽  
Randomized Controlled ◽  
Secondary Outcomes ◽  
Internet Based Intervention

AbstractThe majority of individuals with problematic and pathological gambling remain untreated, and treatment barriers are high. Internet-based interventions can help to address existing barriers, and first studies suggest their potential for this target group. Within a randomized controlled trial (N = 150) with two assessment times (baseline and post-intervention), we aimed to investigate the feasibility, acceptance, and effectiveness of a self-guided Internet-based intervention targeted at gambling problems. We expected a significant reduction in gambling symptoms (primary outcome) and depressive symptoms as well gambling-specific dysfunctional thoughts (secondary outcomes) in the intervention group (IG) compared to a wait-list control group with access to treatment-as-usual (control group, CG) after the intervention period of 8 weeks. Results of the complete cases, per protocol, intention-to-treat (ITT), and frequent user analyses showed significant improvements in both groups for primary and secondary outcomes but no significant between-group differences (ITT primary outcome, F(1,147) = .11, p = .739, ηp2 < .001). Moderation analyses indicated that individuals in the IG with higher gambling and depressive symptoms, older age, and comorbid anxiety symptoms showed significant improvement relative to the CG. The intervention was positively evaluated (e.g., 96.5% rated the program as useful). Possible reasons for the nonsignificant between-group differences are discussed. Future studies should include follow-up assessments and larger samples to address limitations of the present study. Trial Registration ClinicalTrials.gov (NCT03372226), http://clinicaltrials.gov/ct2/show/NCT03372226, date of registration (13/12/2017).

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