Sinonasal Malignant Melanoma

2020 ◽  
pp. 185-196
Author(s):  
Valerie J. Lund
Keyword(s):  
Malignant Melanoma ◽  
Sinonasal Malignant Melanoma

Local control in sinonasal malignant melanoma: Comparing conventional to hypofractionated radiotherapy

Head & Neck ◽  
2017 ◽  
Vol 40 (1) ◽  
pp. 86-93 ◽  
Author(s):  
Jules Lansu ◽  
Willem Martin Klop ◽  
Wilma Heemsbergen ◽  
Arash Navran ◽  
Abrahim Al-Mamgani ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Local Control ◽  
Hypofractionated Radiotherapy ◽  
Sinonasal Malignant Melanoma

Malignant melanoma arising in the frontal sinuses

1997 ◽  
Vol 111 (4) ◽  
pp. 376-378 ◽  
Author(s):  
Samuel M. Jayaraj ◽  
Jonathan D. Hern ◽  
George Mochloulis ◽  
Graham C. Porter
Keyword(s):  
Malignant Melanoma ◽  
Natural History ◽  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Frontal Sinus ◽  
Poor Prognosis ◽  
Review Of The Literature ◽  
History Of ◽  
Frontal Sinuses ◽  
Sinonasal Malignant Melanoma

AbstractSinonasal malignant melanoma is rare and usually occurs in the nasal cavity. Presentation is often varied and occurs late in the natural history of the disease, resulting in a poor prognosis. A case is reported of a patient with malignant melanoma arising from the frontal sinus who presented with a forehead swelling and progressive confusion. A review of the literature on malignant melanoma in the nasal cavity and paranasal sinuses regarding its presentation, site of origin and principles of management is discussed.

scholarly journals Primary Sinonasal Malignant Melanoma: Effect of Clinical and Histopathologic Prognostic Factors on Survival

2017 ◽  
Vol 34 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Sercan Göde ◽  
Göksel Turhal ◽  
Ceyda Tarhan ◽  
Banu Yaman ◽  
Gülşen Kandiloğlu ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Malignant Melanoma ◽  
Sinonasal Malignant Melanoma

Surgery alone versus post-operative radiotherapy for sinonasal malignant melanoma: a meta-analysis

2018 ◽  
Vol 132 (12) ◽  
pp. 1051-1060
Author(s):  
R Hu ◽  
B-B Yang
Keyword(s):  
Overall Survival ◽  
Malignant Melanoma ◽  
Local Control ◽  
Meta Analysis ◽  
Disease Free Survival ◽  
Free Survival ◽  
Rare Malignancy ◽  
One Year ◽  
Disease Free ◽  
Sinonasal Malignant Melanoma

AbstractObjectiveSinonasal malignant melanoma is a relatively rare malignancy with poor prognosis, and effective treatments remain elusive. This analysis aimed to explore whether post-operative radiotherapy conferred any survival advantages in patients with this disease when compared with surgery alone.MethodsPublished studies were identified by searching four electronic databases. The endpoints evaluated were: rates of overall survival, disease-free survival and local control.ResultsTwenty-eight studies including 1392 patients were identified. The results indicated that post-operative radiotherapy led to a significantly better three-year overall survival rate (p= 0.02), and suggested a borderline significant benefit for five-year overall survival (p= 0.05), when compared with surgery alone. However, no statistical advantage was found for disease-free survival, local control or one-year overall survival.ConclusionThis meta-analysis indicated that adjuvant radiotherapy prolonged survival, but showed no benefit for disease-free survival or local control.

scholarly journals Primary sinonasal malignant melanoma with systemic metastasis in a non-gray horse

2020 ◽  
pp. 104063872097856
Author(s):  
Hitoshi Hatai ◽  
Takashi Hatazoe ◽  
Haruka Seo ◽  
Teruaki Tozaki ◽  
Shingo Ishikawa ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Coat Color ◽  
Pelvic Cavity ◽  
Systemic Metastasis ◽  
Initial Biopsy ◽  
Perineal Region ◽  
Left Maxillary Sinus ◽  
Tumor Emboli ◽  
Maxillary Region ◽  
Sinonasal Malignant Melanoma

A 27-y-old Anglo-Arabian gelding with bay coat color was presented with a swelling of the left maxillary region. Fenestration on the left maxilla revealed that the left maxillary sinus was filled with black-red tissue. A portion of the tissue was excised and diagnosed histologically as malignant melanoma. Genotyping of the STX17 gene for gray coat color revealed that the horse did not have the “gray” factor. The horse was euthanized ~3 mo after first presentation. During autopsy, a black-to-gray mass extended from the left nasal cavity to the surrounding paranasal sinus and invaded the hard palate, cribriform plate, and the cranial portion of the left olfactory bulb. Moreover, identical black nodules were present in lymph nodes from the mandible to the larynx, and in the spleen, liver, kidney, and adrenal glands. However, masses were not found in the skin, perineal region, or pelvic cavity. All of the black-to-gray nodules were malignant melanomas that were histologically identical to the initial biopsy; tumor emboli were also found in the kidney. Sinonasal mucosal melanoma is a rare disease in horses.

Treatment outcomes of sinonasal malignant melanoma: a Korean multicenter study

2015 ◽  
Vol 5 (10) ◽  
pp. 950-959 ◽  
Author(s):  
Tae-Bin Won ◽  
Kyu Young Choi ◽  
Chae-Seo Rhee ◽  
Hong-Ryul Jin ◽  
Jong Sook Yi ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Treatment Outcomes ◽  
Multicenter Study ◽  
Sinonasal Malignant Melanoma
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