Public Awareness and Knowledge about Parkinson's Disease: A National Population Based Survey in South Korea

2016 ◽  
Vol 47 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Jinyoung Youn ◽  
Eungseok Oh ◽  
Jinse Park ◽  
Suyeon Park ◽  
Ji Sun Kim ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
South Korea ◽  
Low Socioeconomic Status ◽  
Public Awareness ◽  
Multivariate Logistic Regression Analysis ◽  
Population Based ◽  
Education Level ◽  
Educational Strategies ◽  
Optimal Care

Background: Considering the increasing prevalence of Parkinson's disease (PD), the lack of awareness and knowledge regarding PD may be barriers to the early diagnosis and the provision of optimal care to affected patients. This study aimed to investigate the awareness and knowledge about PD among the general population in South Korea and to identify the factors that are associated with these parameters. Methods: We developed a structured, 22-item questionnaire that consisted of both open-ended and close-ended questions. A total of 1,000 people from the general public were randomly sampled in proportion to the country's population density and were questioned by well-trained interviewers. Multivariate logistic regression analysis was applied to identify the factors associated with awareness and knowledge of PD. Results: Age, household income and education level were independently associated with awareness of PD. Subjects between 40 and 59 years of age and those who had completed more than 12 years of education showed more awareness of PD. Regarding knowledge about PD, younger subjects exhibited the least knowledge compared to respondents between 40 and 59 years of age and those above 60 years of age. Low socioeconomic status tended to be associated with poor knowledge of PD. Conclusions: Awareness and knowledge of PD showed hierarchical gradients with respect to age, income and education level. Pertinent educational strategies and approaches targeting specific subgroups are necessary to improve public awareness and knowledge about PD.

scholarly journals 10 Year Epidemiologic data of Parkinson’s Disease: A Nationwide Population-based Retrospective Cohort of South Korea

2018 ◽  
Author(s):  
Hyoung Seop Kim ◽  
Joon-Byum Kwon ◽  
Hyun-Sun Lim ◽  
Jiook Cha ◽  
Hye Won Kim
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Health Insurance ◽  
South Korea ◽  
National Sample ◽  
Population Based ◽  
Hazard Ratio ◽  
Conflicts Of Interests ◽  
Medical Facilities ◽  
Epidemiological Information

AbstractObjectivesThe aims of this study were to determine the prevalence, incidence, and P/I ratio of Parkinson’s disease (PD) in South Korea and to present basic epidemiological information on PD patients for making effective health policies.MethodsWe used National Health Insurance Service-National Sample Cohort (KNHIS-NSC) data to analyze the prevalence, incidence, and P/I ratio of PD from 2003 to 2013 and then followed up using the NHID in 2008 to obtain the hazard ratio (HR) of death in PD itself and other comorbidities from 2008 to 2013.ResultsThe prevalence and incidence of PD increased rapidly from 72.9 and 32.8 in 2003 to 213.4 and 58.0 in 2013, and the P/I ratio increased from 2.22 in 2003 to 3.62 in 2013. The prevalence, incidence, and P/I ratio of PD were all higher in women than in men. The hazard ratio for death was significantly higher in PD patients (15.36) compared to subjects without the disease. Stroke was the most frequent cause of death in the PD patient population followed by cancer and pneumonia.ConclusionThe prevalence, incidence, and P/I ratio of PD rapidly increased as the years progressed. This indirectly proves that the health insurance system in Korea is efficient and has allowed patients with PD to access medical facilities more easily. However, a newer public healthy strategy should be established for patients with PD because PD itself has a high HR for death, and patients with PD have a high mortality rate when stroke and pneumonia are also involved.DisclosureAll authors have reported no biomedical interests and potential conflicts of interests.

Cancer risk in patients with Parkinson’s disease in South Korea: A nationwide, population-based cohort study

2019 ◽  
Vol 117 ◽  
pp. 5-13 ◽  
Author(s):  
Joo-Hyun Park ◽  
Do-Hoon Kim ◽  
Yong-Gyu Park ◽  
Do-Young Kwon ◽  
Moonyoung Choi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cohort Study ◽  
Cancer Risk ◽  
South Korea ◽  
Population Based

scholarly journals Evaluation of the association between periodontitis and risk of Parkinson’s disease: a nationwide retrospective cohort study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Eunkyung Jeong ◽  
Jun-Beom Park ◽  
Yong-Gyu Park
Keyword(s):  
Parkinson’S Disease ◽  
Metabolic Syndrome ◽  
Parkinson's Disease ◽  
South Korea ◽  
Large Scale ◽  
Proportional Hazards ◽  
Proportional Hazards Model ◽  
Population Based ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model

AbstractThe objective of this study was to examine the association between periodontitis and risk of incident Parkinson’s disease using large-scale cohort data on the entire population of South Korea. Health checkup data from 6,856,180 participants aged 40 and older were provided by the National Health Insurance Service of South Korea between January 1, 2009, and December 31, 2009, and the data were followed until December 31, 2017. The hazard ratio (HR) of Parkinson’s disease and 95% confidence interval (CI) were estimated using a Cox proportional hazards model adjusted for potential confounders. The incidence probability of Parkinson’s disease was positively correlated with the presence of periodontitis. The HR of Parkinson’s disease for the participants without the need of further dentist visits was 0.96 (95% CI 0.921–1.002); the HR of Parkinson’s disease increased to 1.142 (95% CI 1.094–1.193) for the individuals who needed further dentist visits. Compared to individuals without periodontitis and without metabolic syndrome, the HR of incident Parkinson’s disease gradually increased for individuals with periodontitis, with metabolic syndrome, and with both periodontitis and metabolic syndrome. People with periodontitis and metabolic syndrome had the highest HR of incident Parkinson’s disease, at 1.167 (95% CI 1.118–1.219). In conclusion, a weak association between periodontitis and Parkinson’s disease was suggested after adjusting for confounding factors from the population-based large-scale cohort of the entire South Korean population.

scholarly journals Musculoskeletal Disorders, Pain Medication and In-Hospital Mortality among Patients with COVID-19 in South Korea: A Population-Based Cohort Study

2021 ◽  
Vol 18 (13) ◽  
pp. 6804
Author(s):  
Tak-Kyu Oh ◽  
In-Ae Song ◽  
Joon Lee ◽  
Woosik Eom ◽  
Young-Tae Jeon
Keyword(s):  
South Korea ◽  
Hospital Mortality ◽  
Musculoskeletal Disorders ◽  
Multivariate Logistic Regression Analysis ◽  
Population Based ◽  
Pain Medication ◽  
Multivariate Logistic Regression ◽  
Lower Back ◽  
Inflammatory Drugs ◽  
Strong Opioids

We aimed to investigate whether comorbid musculoskeletal disorders (MSD)s and pain medication use was associated with in-hospital mortality among patients with coronavirus disease 2019 (COVID-19). Adult patients (≥20 years old) with a positive COVID-19 diagnosis until 5 June 2020 were included in this study, based on the National Health Insurance COVID-19 database in South Korea. MSDs included osteoarthritis, neck pain, lower back pain, rheumatoid arthritis, and others, while pain medication included paracetamol, gabapentin, pregabalin, glucocorticoid, nonsteroidal anti-inflammatory drugs (NSAIDs), opioids (strong and weak opioids), and benzodiazepine. Primary endpoint was in-hospital mortality. A total of 7713 patients with COVID-19 were included, and in-hospital mortality was observed in 248 (3.2%) patients. In multivariate logistic regression analysis, no MSDs (p > 0.05) were significantly associated with in-hospital mortality. However, in-hospital mortality was 12.73 times higher in users of strong opioids (odds ratio: 12.73, 95% confidence interval: 2.44–16.64; p = 0.002), while use of paracetamol (p = 0.973), gabapentin or pregabalin (p = 0.424), glucocorticoid (p = 0.673), NSAIDs (p = 0.979), weak opioids (p = 0.876), and benzodiazepine (p = 0.324) was not associated with in-hospital mortality. In South Korea, underlying MSDs were not associated with increased in-hospital mortality among patients with COVID-19. However, use of strong opioids was significantly associated with increased in-hospital mortality among the patients.

Migraine is related to an increased risk of Parkinson’s disease: A population-based, propensity score-matched, longitudinal follow-up study

Cephalalgia ◽  
2016 ◽  
Vol 36 (14) ◽  
pp. 1316-1323 ◽  
Author(s):  
Hsin-I Wang ◽  
Yu-Chun Ho ◽  
Ya-Ping Huang ◽  
Shin-Liang Pan
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Survival Rate ◽  
Propensity Score ◽  
Population Based ◽  
Free Survival ◽  
Follow Up Study ◽  
Increased Risk ◽  
Migraine Group

Background The association between migraine and Parkinson’s disease (PD) remains controversial. The purpose of the present population-based, propensity score-matched follow-up study was to investigate whether migraineurs are at a higher risk of developing PD. Methods A total of 41,019 subjects aged between 40 and 90 years with at least two ambulatory visits with a diagnosis of migraine in 2001 were enrolled in the migraine group. A logistic regression model that included age, sex, pre-existing comorbidities and socioeconomic status as covariates was used to compute the propensity score. The non-migraine group consisted of 41,019 propensity score-matched, randomly sampled subjects without migraine. The PD-free survival rate were estimated using the Kaplan–Meier method. Stratified Cox proportional hazard regression was used to estimate the effect of migraine on the risk of developing PD. Results During follow-up, 148 subjects in the migraine group and 101 in the non-migraine group developed PD. Compared to the non-migraine group, the hazard ratio of PD for the migraine group was 1.64 (95% confidence interval: 1.25–2.14, p = 0.0004). The PD-free survival rate for the migraine group was significantly lower than that for the non-migraine group ( p = 0.0041). Conclusions This study showed an increased risk of developing PD in patients with migraine.

scholarly journals Trend of recognizing depression symptoms and antidepressants use in newly diagnosed Parkinson's disease: Population‐based study

2021 ◽  
Author(s):  
Khalid Orayj ◽  
Tahani Almeleebia ◽  
Easwaran Vigneshwaran ◽  
Sultan Alshahrani ◽  
Sirajudeen. S. Alavudeen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Population Based ◽  
Depression Symptoms ◽  
Newly Diagnosed ◽  
Population Based Study

scholarly journals Diffusion Tensor Imaging Along the Perivascular Space Index in Different Stages of Parkinson’s Disease

2021 ◽  
Vol 13 ◽  
Author(s):  
Xinxin Ma ◽  
Shuhua Li ◽  
Chunmei Li ◽  
Rui Wang ◽  
Min Chen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Diffusion Tensor ◽  
Multivariate Logistic Regression Analysis ◽  
Perivascular Space ◽  
Periventricular White Matter ◽  
Perivascular Spaces ◽  
Glymphatic System ◽  
Multiple Variables ◽  
Association Fibers

Background: The aim of this study was to evaluate the glymphatic system activity in patients with Parkinson’s disease (PD) using the diffusion tensor image analysis along the perivascular space (DTI-ALPS) methods.Methods: In total, 71 patients with idiopathic PD and 36 age- and sex-matched normal controls (NCs) were involved. Patients with PD were divided into early (n = 35) and late (n = 36) subgroups, based on Hoehn and Yahr (HY) stages. We calculated the diffusivity along the perivascular spaces (ALPS), as well as projection fibers and association fibers separately, to acquire the ALPS index. Enlarged perivascular spaces (EPVS) and periventricular white matter hyperintensities were also rated. Differences in ALPS index between the PD group and NCs and between two PD subgroups and NCs were compared. In addition, a multivariate logistic regression analysis was conducted to investigate the association between ALPS index and clinical variables.Results: Patients with PD revealed lower ALPS index than NCs (p = 0.010). The late PD group exhibited significantly lower ALPS index than NCs (p = 0.006). However, there were no marked differences noticed in ALPS index between NCs and early PD group and between the two PD subgroups. In the early PD group, there was a significantly positive correlation between ALPS index and Mini-Mental State Examination (MMSE) score (β = 0.021, p = 0.029) and a negative correlation between ALPS index and EPVS score (β = −0.050, p = 0.034), after controlling for multiple variables. In the late PD group, ALPS index was inversely associated with age (β = −0.012, p = 0.004).Conclusion: Impairment of the glymphatic system is involved in PD. DTI-ALPS index could be a promising biomarker of glymphatic system in PD.

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