Fetal Serum β2-Microglobulin and Postnatal Renal Function in Lower Urinary Tract Obstruction Treated with Vesicoamniotic Shunt

2016 ◽  
Vol 42 (1) ◽  
pp. 17-27 ◽  
Author(s):  
Andrew H. Chon ◽  
Gustavo H. de Oliveira ◽  
Kevin V. Lemley ◽  
Lisa M. Korst ◽  
Ryan D. Assaf ◽  
...  
Keyword(s):  
Renal Function ◽  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Urinary Tract Obstruction ◽  
Lower Urinary Tract Obstruction ◽  
Fetal Serum ◽  
Vesicoamniotic Shunt ◽  
Lower Urinary

758: Fetal serum beta 2-microblogulin and postnatal renal function in lower urinary tract obstruction

2016 ◽  
Vol 214 (1) ◽  
pp. S397-S398
Author(s):  
Ramen H. Chmait ◽  
Andrew H. Chon ◽  
Gustavo H. de Oliveira ◽  
Kevin V. Lemley ◽  
Lisa M. Korst ◽  
...  
Keyword(s):  
Renal Function ◽  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Urinary Tract Obstruction ◽  
Lower Urinary Tract Obstruction ◽  
Fetal Serum ◽  
Beta 2 ◽  
Lower Urinary

Evaluation of Sequential Urine Analysis when Selecting Candidates for Vesicoamniotic Shunting in Lower Urinary Tract Obstruction

2021 ◽  
pp. 1-7
Author(s):  
Antoine Koch ◽  
Romain Favre ◽  
Anne-Sophie Weingertner ◽  
Ariane Zaloszyc ◽  
Monique Kohler ◽  
...  
Keyword(s):  
Renal Function ◽  
Urinary Tract ◽  
Normal Renal Function ◽  
Lower Urinary Tract ◽  
Urine Analysis ◽  
Urinary Tract Obstruction ◽  
Neonatal Deaths ◽  
Lower Urinary Tract Obstruction ◽  
Vesicoamniotic Shunt ◽  
Lower Urinary

Objective: The objective of our study was to assess the utility of sequential fetal urine analysis in severe lower urinary tract obstruction (LUTO) when selecting cases suitable for vesicoamniotic shunting. Material and Methods: This was a retrospective cohort study of cases of severe LUTO treated in our fetal medicine center from 1994 to 2013. Two fetal bladder samples were taken 24–48 h apart to assess renal function. A vesicoamniotic shunt was inserted in case of improvement in urinary biochemistry between the 2 samples. We assessed perinatal morbidity and mortality and renal function at 5 years. Results: Among a total of 26 LUTO cases with sequential urine analysis, 5 showed normal urinary biochemistry, 13 were abnormal, and 8 improved between the 2 samples. These 8 cases underwent vesicoamniotic shunt placement, leading to the birth of 6/8 (75%) live infants, 5/6 (83%) of whom had normal renal function at 5 years. The 5 cases with normal biochemistry occasioned 2 neonatal deaths and 3 children with normal renal function at 5 years. Elective termination of pregnancy was requested by parents for the fetuses exhibiting abnormal biochemistry. Conclusion: An improvement in urinary biochemistry between 2 sequential fetal bladder punctures in severe LUTO could be an effective criterion in the selection of candidates for vesicoamniotic shunting. However, the benefit of a shunt in fetuses with normal amniotic fluid remains to be evaluated in clinical trials.

Comparison of biochemical analysis of fetal serum and fetal urine in the prediction of postnatal renal outcome in lower urinary tract obstruction

2018 ◽  
Vol 38 (8) ◽  
pp. 555-560 ◽  
Author(s):  
Emmanuel Spaggiari ◽  
Julien J. Stirnemann ◽  
Sara Benedetti ◽  
Sophie Dreux ◽  
Laurent J. Salomon ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Biochemical Analysis ◽  
Urinary Tract Obstruction ◽  
Renal Outcome ◽  
Lower Urinary Tract Obstruction ◽  
Fetal Serum ◽  
Fetal Urine ◽  
Lower Urinary
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