scholarly journals OC14.05: Comparison of fetal outcome in lower urinary tract obstruction treated with the Harrison® vs Somatex® vesicoamniotic shunt <17+0 weeks

2018 ◽  
Vol 52 ◽  
pp. 34-34
Author(s):  
A. Geipel ◽  
T. Spicher ◽  
A. Hellmund ◽  
B.S. Strizek ◽  
R. Stadie ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Urinary Tract Obstruction ◽  
Fetal Outcome ◽  
Lower Urinary Tract Obstruction ◽  
Vesicoamniotic Shunt ◽  
Lower Urinary

scholarly journals Fetal Lower Urinary Tract Obstruction: An Update

2015 ◽  
Vol 8 (1) ◽  
pp. 124-135 ◽  
Author(s):  
Russell S. Miller
Keyword(s):  
Urinary Tract ◽  
Amniotic Fluid ◽  
Lower Urinary Tract ◽  
Urinary Tract Obstruction ◽  
Obstructive Uropathy ◽  
Fluid Volume ◽  
Amniotic Fluid Volume ◽  
Lower Urinary Tract Obstruction ◽  
Vesicoamniotic Shunt ◽  
Lower Urinary

Fetal lower urinary tract obstruction [LUTO] represents a rare, heterogeneous group of uropathies involving mechanical or functional blockage at the bladder outlet of varying severity. While ultrasound is a fair screening tool for the antenatal detection of this condition, it cannot reliably determine the underlying etiology of LUTO presentations. Sonographic assessment of renal appearance and amniotic fluid volume, as well as urinary analyte analysis, are the most useful predictors of preserved renal function in fetal LUTO, although they, too, are limited in their ability to predict outcomes on an individual basis. Animal models suggest that obstructive uropathy likely causes irreparable damage to the renal and urinary collecting system injury early in pregnancy. When LUTO is associated with abnormal amniotic fluid volume, long-standing oligohydramnios may result in lethal pulmonary hypoplasia. Data evaluating the efficacy of vesicoamniotic shunt therapy for the treatment of fetal LUTO are inconclusive. While vesicoamniotic shunting may modify disease lethality by restoring fluid volume, renal and other genitourinary benefits are minimal if not altogether absent, arguably supporting the belief that bladder decompression is being performed after irreversible injury has already been sustained.

scholarly journals Postnatal Management in Congenital Lower Urinary Tract Obstruction With and Without Prenatal Vesicoamniotic Shunt

2021 ◽  
Vol 9 ◽  
Author(s):  
Marietta Jank ◽  
Raimund Stein ◽  
Nina Younsi
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Urinary Tract Obstruction ◽  
Outlet Obstruction ◽  
Early Management ◽  
Postnatal Management ◽  
Urinary Drainage ◽  
Lower Urinary Tract Obstruction ◽  
Vesicoamniotic Shunt ◽  
Lower Urinary

Purpose: Congenital lower urinary tract obstruction (cLUTO) includes a heterogeneous group of conditions caused by a functional or mechanical outlet obstruction. Early vesicoamniotic shunting (VAS) possibly reduces the burden of renal impairment. Postpartum, pediatric urologists are confronted with neonates who have a shunt in place and a potentially impassable urethra with a narrow caliber. Early management of these patients can be challenging. Here, we would like to share the approach we have developed over time.Materials and Methods: We conducted a single-center retrospective analysis from 2016 to 2020 and included all patients diagnosed with cLUTO. Data focusing on time point and type of intervention was collected. Furthermore, patients with temporary diversion via a percutaneous VAS were selected for a more detailed review.Results: In total, 71 cases of cLUTO were identified during the study period. Within this group, 31 neonates received postnatal management and surgical intervention in our center. VAS was performed in 55% of these cases (N = 17). The postnatal treatment varied between transurethral or suprapubic catheterization and early Blocksom vesicostomy. In five infants with VAS, the urinary drainage was secured through the existing VAS by inserting a gastric tube (N = 1) or a 4.8 Fr JJ-stent (N = 4). To our knowledge, this is the first report of a stent-in-stent scheme, which can remain indwelling until the definite treatment.Conclusion: Having a secure urine drainage through a VAS allows the often premature infant to grow until definite surgery can be performed. This avoids placing a vesicostomy, which requires anesthesia.

Fetal Serum β2-Microglobulin and Postnatal Renal Function in Lower Urinary Tract Obstruction Treated with Vesicoamniotic Shunt

2016 ◽  
Vol 42 (1) ◽  
pp. 17-27 ◽  
Author(s):  
Andrew H. Chon ◽  
Gustavo H. de Oliveira ◽  
Kevin V. Lemley ◽  
Lisa M. Korst ◽  
Ryan D. Assaf ◽  
...  
Keyword(s):  
Renal Function ◽  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Urinary Tract Obstruction ◽  
Lower Urinary Tract Obstruction ◽  
Fetal Serum ◽  
Vesicoamniotic Shunt ◽  
Lower Urinary

Evaluation of Sequential Urine Analysis when Selecting Candidates for Vesicoamniotic Shunting in Lower Urinary Tract Obstruction

2021 ◽  
pp. 1-7
Author(s):  
Antoine Koch ◽  
Romain Favre ◽  
Anne-Sophie Weingertner ◽  
Ariane Zaloszyc ◽  
Monique Kohler ◽  
...  
Keyword(s):  
Renal Function ◽  
Urinary Tract ◽  
Normal Renal Function ◽  
Lower Urinary Tract ◽  
Urine Analysis ◽  
Urinary Tract Obstruction ◽  
Neonatal Deaths ◽  
Lower Urinary Tract Obstruction ◽  
Vesicoamniotic Shunt ◽  
Lower Urinary

Objective: The objective of our study was to assess the utility of sequential fetal urine analysis in severe lower urinary tract obstruction (LUTO) when selecting cases suitable for vesicoamniotic shunting. Material and Methods: This was a retrospective cohort study of cases of severe LUTO treated in our fetal medicine center from 1994 to 2013. Two fetal bladder samples were taken 24–48 h apart to assess renal function. A vesicoamniotic shunt was inserted in case of improvement in urinary biochemistry between the 2 samples. We assessed perinatal morbidity and mortality and renal function at 5 years. Results: Among a total of 26 LUTO cases with sequential urine analysis, 5 showed normal urinary biochemistry, 13 were abnormal, and 8 improved between the 2 samples. These 8 cases underwent vesicoamniotic shunt placement, leading to the birth of 6/8 (75%) live infants, 5/6 (83%) of whom had normal renal function at 5 years. The 5 cases with normal biochemistry occasioned 2 neonatal deaths and 3 children with normal renal function at 5 years. Elective termination of pregnancy was requested by parents for the fetuses exhibiting abnormal biochemistry. Conclusion: An improvement in urinary biochemistry between 2 sequential fetal bladder punctures in severe LUTO could be an effective criterion in the selection of candidates for vesicoamniotic shunting. However, the benefit of a shunt in fetuses with normal amniotic fluid remains to be evaluated in clinical trials.

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