Assessing the Impact of Atopic Dermatitis on the Patients' Parents with the Visual Instrument ‘Caregiver-PRISM'

Dermatology ◽  
2016 ◽  
Vol 232 (4) ◽  
pp. 490-495 ◽  
Author(s):  
Elena Marinello ◽  
Dennis Linder ◽  
Andrea Spoto ◽  
Katie Palmer ◽  
Peter Michael Rohrer ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
The Impact ◽  
Visual Instrument

scholarly journals The impact of atopic dermatitis on health-related quality of life in Taiwan

2021 ◽  
Author(s):  
Bing-Jun Hsieh ◽  
Dereck Shen ◽  
Chia-Jung Hsu ◽  
Tom C. Chan ◽  
Yung-Tsu Cho ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Impact

scholarly journals Congenital Deficiency of Conventional Dendritic Cells Promotes the Development of Atopic Dermatitis-Like Inflammation

2021 ◽  
Vol 12 ◽  
Author(s):  
Yotaro Nishikawa ◽  
Tomohiro Fukaya ◽  
Takehito Fukui ◽  
Tomofumi Uto ◽  
Hideaki Takagi ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Atopic Dermatitis ◽  
Immune Responses ◽  
Skin Barrier ◽  
Lymphoid Cells ◽  
Congenital Deficiency ◽  
T Cell Immune Responses ◽  
Group 2 ◽  
And Function ◽  
The Impact

Atopic dermatitis (AD) is a common pruritic inflammatory skin disease characterized by impaired epidermal barrier function and dysregulation of Thelper-2 (TH2)-biased immune responses. While the lineage of conventional dendritic cells (cDCs) are implicated to play decisive roles in T-cell immune responses, their requirement for the development of AD remains elusive. Here, we describe the impact of the constitutive loss of cDCs on the progression of AD-like inflammation by using binary transgenic (Tg) mice that constitutively lacked CD11chi cDCs. Unexpectedly, the congenital deficiency of cDCs not only exacerbates the pathogenesis of AD-like inflammation but also elicits immune abnormalities with the increased composition and function of granulocytes and group 2 innate lymphoid cells (ILC2) as well as B cells possibly mediated through the breakdown of the Fms-related tyrosine kinase 3 ligand (Flt3L)-mediated homeostatic feedback loop. Furthermore, the constitutive loss of cDCs accelerates skin colonization of Staphylococcus aureus (S. aureus), that associated with disease flare. Thus, cDCs maintains immune homeostasis to prevent the occurrence of immune abnormalities to maintain the functional skin barrier for mitigating AD flare.

scholarly journals Assessment of the Impact of the A-896G Polymorphism of the TLR-4 Gene in Adults with Extrinsic and Intrinsic Atopic Dermatitis

2019 ◽  
Vol 143 (2) ◽  
pp. AB124
Author(s):  
Yuriy Bisyuk ◽  
Olexander Litus ◽  
Nadiya Derkach ◽  
Viktor Litus ◽  
Lawrence M. Dubuske
Keyword(s):  
Atopic Dermatitis ◽  
The Impact

Comparison of Personality Traits among Patients with Psoriasis, Atopic Dermatitis, and Stress: A Pilot Study

Dermatology ◽  
2020 ◽  
Vol 236 (4) ◽  
pp. 324-328 ◽  
Author(s):  
Lynda Grine ◽  
Giulia Tochtermann ◽  
Hilde Lapeere ◽  
Nele Maes ◽  
Günther F.L. Hofbauer ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Pilot Study ◽  
Personality Traits ◽  
Skin Diseases ◽  
Work Related Stress ◽  
Work Related ◽  
Chronic Skin ◽  
Related Stress ◽  
Chronic Skin Diseases ◽  
The Impact

Background: Psoriasis and atopic dermatitis are chronic skin diseases that greatly affect the quality of life. Both diseases can be triggered or exacerbated by stress. Objective: We aimed to differentiate personality traits between patients with chronic skin conditions and people treated for stress in a pilot study. Methods: Patients participating voluntarily in educational programs in Belgium and Switzerland were recruited to complete personality trait questionnaires, including the Temperament and Character Inventory (TCI) and the Tridimensional Personality Questionnaire (TPQ). A comparison was made with patients treated for work-related stress. Results: A total of 48 and 91 patients suffering from skin diseases and work-related stress, respectively, were included in the study. Based on the questionnaires, we found that dermatology patients were less persistent and impulsive than those with work-related stress. Dermatology patients also exhibited more rigidness and less focus on performance. Finally, patients with work-related stress seem more likely to change in response to health-promoting programs than patients with chronic dermatoses. Conclusion: Patients with chronic skin diseases may perceive and cope with stress differently in comparison to patients with work-related stress due to inherent personality traits. Therefore, stress coping mechanisms may differ among different diseases. More research is needed into the design of educational interventions and the impact of personality traits in disease-specific groups.

Sign in / Sign up

Export Citation Format

Share Document