scholarly journals Pancreatic Acinar Cell Carcinoma

2016 ◽  
Vol 10 (1) ◽  
pp. 179-185 ◽  
Author(s):  
Dominique Béchade ◽  
Marie Desjardin ◽  
Emma Salmon ◽  
Grégoire Désolneux ◽  
Yves Bécouarn ◽  
...  
Keyword(s):  
Ct Scan ◽  
Cell Carcinoma ◽  
Fine Needle Aspiration ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Abdominal Ct ◽  
Fine Needle ◽  
Pancreatic Acinar Cell Carcinoma ◽  
Abdominal Ct Scan

Pancreatic acinar cell carcinoma (ACC) is a rare malignant neoplasm that accounts for 1–2% of all pancreatic neoplasms. Here we report two cases of ACC and describe their clinical features, the therapies used to treat them, and their prognosis. The first patient was a 65-year-old woman who had an abdominal CT scan for a urinary infection. Fortuitously, a rounded and well-delimited corporeal pancreatic tumor was discovered. An endoscopic ultrasound (EUS)-guided fine needle aspiration revealed an ACC. During the puncture, a hypoechoic cavity appeared inside the lesion, corresponding to a probable necrotic area. Treatment consisted of a distal splenopancreatectomy. The second patient was a 75-year-old man who complained of abdominal pain. An abdominal CT scan showed a cephalic pancreatic lesion and two hepatic metastases. An EUS-guided fine needle aspiration showed a pancreatic ACC. The patient received chemotherapy with gemcitabine plus oxaliplatin (GEMOX regimen), which enabled an objective response after 6 cycles.

scholarly journals Two cases of pancreatic acinar cell carcinoma diagnosed by ultrasound-guided fine needle aspiration

Suizo ◽  
2015 ◽  
Vol 30 (6) ◽  
pp. 805-811 ◽  
Author(s):  
Maki KANZAWA ◽  
Naokazu MIYAMOTO ◽  
Hidehiro SAWA ◽  
Daisuke KURODA ◽  
Tsuyoshi SANUKI ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Fine Needle Aspiration ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Pancreatic Acinar Cell Carcinoma

scholarly journals Liver metastases of pancreatic acinar cell carcinoma with marked nuclear atypia and pleomorphism diagnosed by EUS FNA cytology : A case report with emphasis on FNA cytological findings

CytoJournal ◽  
2006 ◽  
Vol 3 ◽  
pp. 29 ◽  
Author(s):  
Hong Q Peng ◽  
Peter Darwin ◽  
John C Papadimitriou ◽  
Cinthia B Drachenberg
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Fine Needle Aspiration ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Endocrine Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Acinar cell carcinoma of the pancreas is a rare neoplasm. Although this tumor has been well characterized histologically, the morphological patterns in Fine Needle Aspiration Cytology have not been well defined. Unlike ductal adenocarcinomas, endocrine tumors, and solid pseudopapillary tumors of the pancreas with their characteristic FNA cytological features, acinar cell carcinomas pose a particular diagnostic challenge by sharing many cytomorphologic features with endocrine tumors of the pancreas. Case presentation: A 37-year-old man presented with lower chest and left upper quadrant abdominal pain. Computed tomography revealed a 7.8 x 7.3 cm irregular, partially cystic mass in the body and tail of the pancreas, and two lesions in the liver compatible with metastases. Subsequently, the patient underwent endoscopic ultrasound-guided fine needle aspiration on one of the two metastatic liver masses. Conclusion: We describe a case of pancreatic acinar cell carcinoma with unusual cytomorphologic features mimicking an endocrine tumor of pancreas, encountered in endoscopic ultrasound-guided fine needle aspiration of a metastatic liver mass and discuss the diagnostic approach for this unusual pancreatic tumor in fine needle aspiration cytology.

scholarly journals Hepatic Squamous Cell Carcinoma Diagnosed by Endoscopic Ultrasound-Guided Fine-Needle Aspiration

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Koki Yamada ◽  
Susumu Shinoura ◽  
Kaoru Kikuchi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Ct Scan ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Whole Body ◽  
Ultrasound Guided ◽  
Fine Needle

Primary hepatic squamous cell carcinoma (SCC) is a rare malignancy with aggressive clinical features. This is the first case report of a primary hepatic SCC diagnosed by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), which is a reliable and safe procedure for the histopathological diagnosis of liver lesions, even if the percutaneous approach is difficult due to ascites or hypervascularity at the puncture site. A 52-year-old man presented to the emergency department of a tertiary referral hospital with right upper quadrant abdominal pain and abdominal distention. Given the laboratory data, a diagnosis of spontaneous bacterial peritonitis (SBP) was made. Concurrently, an abdominal computed tomography (CT) scan revealed an 8 cm hypodense mass with delayed peripheral enhancement in the left hepatic lobe and paraaortic and perihepatic lymphadenopathy. As persistent ascites precluded percutaneous liver biopsy, we performed EUS-FNA of the liver mass, and the obtained specimen showed SCC. As otorhinolaryngological consultation and whole-body investigations, including chest CT, upper and lower endoscopy, and positron emission tomography CT, were all unremarkable except for the liver lesion and lymph nodes, a diagnosis of primary hepatic SCC with systemic lymph node metastasis was made. After treatment of SBP with antibiotics, we initiated chemotherapy concurrent with radiation therapy, adapted to his liver function. Radiation and three cycles of chemotherapy were not effective as the disease progressed, as seen on the follow-up CT scan, and the patient died of hepatic failure on the 134th day after diagnosis. In conclusion, EUS-FNA was a reliable method for tissue sampling in liver malignancies, particularly in selected patients with contraindications for percutaneous biopsy.

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