Metastatic pancreatic acinar cell carcinoma in a younger male with marked AFP production: A potential pitfall on fine needle aspiration biopsy

2016 ◽  
Vol 45 (2) ◽  
pp. 133-136 ◽  
Author(s):  
Kari Valente ◽  
George Yacoub ◽  
James O. Cappellari ◽  
Graham Parks
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Fine Needle ◽  
Pancreatic Acinar Cell Carcinoma ◽  
Afp Production

scholarly journals Two cases of pancreatic acinar cell carcinoma diagnosed by ultrasound-guided fine needle aspiration

Suizo ◽  
2015 ◽  
Vol 30 (6) ◽  
pp. 805-811 ◽  
Author(s):  
Maki KANZAWA ◽  
Naokazu MIYAMOTO ◽  
Hidehiro SAWA ◽  
Daisuke KURODA ◽  
Tsuyoshi SANUKI ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Fine Needle Aspiration ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Pancreatic Acinar Cell Carcinoma

scholarly journals Liver metastases of pancreatic acinar cell carcinoma with marked nuclear atypia and pleomorphism diagnosed by EUS FNA cytology : A case report with emphasis on FNA cytological findings

CytoJournal ◽  
2006 ◽  
Vol 3 ◽  
pp. 29 ◽  
Author(s):  
Hong Q Peng ◽  
Peter Darwin ◽  
John C Papadimitriou ◽  
Cinthia B Drachenberg
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Fine Needle Aspiration ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Endocrine Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Acinar cell carcinoma of the pancreas is a rare neoplasm. Although this tumor has been well characterized histologically, the morphological patterns in Fine Needle Aspiration Cytology have not been well defined. Unlike ductal adenocarcinomas, endocrine tumors, and solid pseudopapillary tumors of the pancreas with their characteristic FNA cytological features, acinar cell carcinomas pose a particular diagnostic challenge by sharing many cytomorphologic features with endocrine tumors of the pancreas. Case presentation: A 37-year-old man presented with lower chest and left upper quadrant abdominal pain. Computed tomography revealed a 7.8 x 7.3 cm irregular, partially cystic mass in the body and tail of the pancreas, and two lesions in the liver compatible with metastases. Subsequently, the patient underwent endoscopic ultrasound-guided fine needle aspiration on one of the two metastatic liver masses. Conclusion: We describe a case of pancreatic acinar cell carcinoma with unusual cytomorphologic features mimicking an endocrine tumor of pancreas, encountered in endoscopic ultrasound-guided fine needle aspiration of a metastatic liver mass and discuss the diagnostic approach for this unusual pancreatic tumor in fine needle aspiration cytology.

scholarly journals Pancreatic Acinar Cell Carcinoma

2016 ◽  
Vol 10 (1) ◽  
pp. 179-185 ◽  
Author(s):  
Dominique Béchade ◽  
Marie Desjardin ◽  
Emma Salmon ◽  
Grégoire Désolneux ◽  
Yves Bécouarn ◽  
...  
Keyword(s):  
Ct Scan ◽  
Cell Carcinoma ◽  
Fine Needle Aspiration ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Abdominal Ct ◽  
Fine Needle ◽  
Pancreatic Acinar Cell Carcinoma ◽  
Abdominal Ct Scan

Pancreatic acinar cell carcinoma (ACC) is a rare malignant neoplasm that accounts for 1–2% of all pancreatic neoplasms. Here we report two cases of ACC and describe their clinical features, the therapies used to treat them, and their prognosis. The first patient was a 65-year-old woman who had an abdominal CT scan for a urinary infection. Fortuitously, a rounded and well-delimited corporeal pancreatic tumor was discovered. An endoscopic ultrasound (EUS)-guided fine needle aspiration revealed an ACC. During the puncture, a hypoechoic cavity appeared inside the lesion, corresponding to a probable necrotic area. Treatment consisted of a distal splenopancreatectomy. The second patient was a 75-year-old man who complained of abdominal pain. An abdominal CT scan showed a cephalic pancreatic lesion and two hepatic metastases. An EUS-guided fine needle aspiration showed a pancreatic ACC. The patient received chemotherapy with gemcitabine plus oxaliplatin (GEMOX regimen), which enabled an objective response after 6 cycles.

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