The Prevalence of Vitreomacular Interface Pathology in a Spanish Tertiary Hospital

2016 ◽  
Vol 235 (3) ◽  
pp. 179-183 ◽  
Author(s):  
Ignacio Flores-Moreno ◽  
Luis Arias-Barquet ◽  
María Vidal-Martí ◽  
Alex Muñoz-Blanco ◽  
Marcos J. Rubio-Caso ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Posterior Vitreous Detachment ◽  
Rare Condition ◽  
Tertiary Hospital ◽  
Population Based ◽  
Vitreomacular Adhesion ◽  
Full Thickness Macular Hole ◽  
Vitreomacular Interface ◽  
Hospital Study ◽  
Pathologic State

Purpose: To determine the prevalence of vitreomacular interface (VMI) pathology, using spectral-domain optical coherence tomography (SD-OCT). Methods: VMI status was classified into macular posterior vitreous detachment (PVD), focal vitreomacular adhesion (VMA; ≤1,500 μm), broad VMA (>1,500 μm), focal vitreomacular traction (VMT; ≤1,500 μm), broad VMT (>1,500 μm), full-thickness macular hole (FTMH) with the presence of VMT, and FTMH without the presence of VMT. Results: A total of 1,976 eyes were included. A nonpathologic VMI was observed in 1,875 eyes (94.8%), including 1,050 (53.1%) with PVD, 120 (6.1%) with focal VMA and 705 (35.6%) with broad VMA. A pathologic state of the VMI was diagnosed in 101 eyes (5.1%). Thirty-three eyes (1.7%) were classified as focal VMT, 29 (1.4%) as broad VMT, 39 (1.9%) as FTMH, resulting in 6 small, 12 medium and 21 large FTMHs, six eyes had VMT associated to FTMH. Conclusions: Even in a tertiary care, retinal referral practice, VMI pathology is a relatively rare condition. There was a higher prevalence in a tertiary hospital study compared to population-based studies.

scholarly journals Physiology of Vitreous and Vitreomacular Interface and Age-Related Changes

2018 ◽  
pp. 213-219
Keyword(s):  
Extracellular Matrix ◽  
Posterior Vitreous Detachment ◽  
Natural Aging ◽  
Posterior Segment ◽  
Vitreomacular Adhesion ◽  
Vitreoretinal Interface ◽  
Age Related ◽  
Ocular Structure ◽  
Vitreomacular Interface ◽  
Age Related Changes

Vitreous is an important ocular structure in the normal physiology and pathologic conditions of the posterior segment. Vitreous is a gel-like composite structure and forms an extracellular matrix that occupies the biggest space in the eye. The healthy vitreous gel reduces oxygen tension and protects vitreous, retina, and lens from oxidative damage. Vitreous plays an important role in the refraction of the eye, preserving the transparency with regular interaction of the macromolecules contained therein. Vitreous suffer from continuous physical tension and this results in important changes. Particularly age-related degeneration in the structure of the vitreous gel leads to a decrease in vitreoretinal adhesion. As part of natural aging, the posterior vitreous detachment process may become pathologic when the vitreoretinal interface weakens simultaneously with vitreous liquefaction. In this process, vision-threatening diseases such as vitreomacular adhesion, vitreomacular traction, and macula hole may appear.

scholarly journals Vitreomacular Adhesion, Vitreomacular Traction, and Concurrent Diseases

2018 ◽  
pp. 256-261
Keyword(s):  
Posterior Vitreous Detachment ◽  
Age Related Macular Degeneration ◽  
Optic Coherence Tomography ◽  
Retinal Diseases ◽  
Vitreomacular Adhesion ◽  
Vitreous Detachment ◽  
Age Related ◽  
Vitreomacular Interface ◽  
Vascular Occlusions ◽  
Endothelial Growth Factor

The introduction of the optic coherence tomography in ophthalmology has been enabled us to understand the relationship between vitreomacular interface pathologies and concurrent retinal diseases. It is known that vitreomacular adhesion (VMA) and traction (VMT) develops as a result of an incomplete posterior vitreous detachment. VMA/VMT usually coincidence with age-related macular degeneration, diabetic macular edema, and retinal vascular occlusions. Some studies suggested that the complete posterior vitreous detachment is protective against these kinds of retinal diseases. It is proclaimed that VMA/VMT may have a role in the etiology and progression of these retinal diseases. And also, in the majority of the studies, it is proposed that VMA/VMT may interfere with the treatment and even worsen the result of the anti-vascular endothelial growth factor (Anti-VEGF) therapy which is used within the treatment regime of these retinal diseases. It is obvious that further studies are needed to clarify the cause-result relationship and the effectiveness of the treatment for the concurrent retinal diseases.

scholarly journals Epidemiology of Vitreomacular Interface Disorders

2018 ◽  
pp. 220-223
Keyword(s):  
Macular Hole ◽  
Epiretinal Membrane ◽  
Visual Loss ◽  
Disease Duration ◽  
Posterior Vitreous Detachment ◽  
Vitreomacular Adhesion ◽  
Membrane Formation ◽  
Vitreous Detachment ◽  
Vitreomacular Interface ◽  
Epidemiological Characteristics

Vitreomacular interface disorders consist of a series of diseases including vitreomacular adhesion, vitreomacular traction, macular hole, and epiretinal membrane formation. They occur due to the failed progression of normal posterior vitreous detachment. Affected patients may present with metamorphopsia and varying degrees of visual loss depending on the severity of foveal disturbance and disease duration. The aim of this review is to define the epidemiological characteristics of these groups of disorders which show an increased incidence and prevalence with age in parallel with the occurrence of posterior vitreous detachment.

scholarly journals Clinic, Diagnosis, and Classification in Vitreomacular interface Diseases

2018 ◽  
pp. 231-235
Keyword(s):  
Optical Coherence Tomography ◽  
Full Thickness ◽  
Pathological Changes ◽  
Vitreomacular Adhesion ◽  
Vitreoretinal Interface ◽  
Full Thickness Macular Hole ◽  
Vitreoretinal Traction ◽  
Diagnosis And Classification ◽  
Vitreomacular Interface ◽  
Lamellar Hole

With the developing optical coherence tomography technology it was possible to describe the vitreoretinal interface changes in detail. In this article, we aimed to evaluate the physiologic and pathological changes, vitreomacular adhesion (VMA), vitreoretinal traction (VMT), epiretinal membrane (ERM), full-thickness macular hole (FTMH), lamellar hole and pseudohole in the vitreoretinal interface.

scholarly journals Vitreo-macular Interface Abnormalities in Diabetic and Non-Diabetic Patients Using Optical Coherence Tomography

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Uzma Hamza ◽  
Waqas Asghar ◽  
Qasim Lateef Chaudhry ◽  
Muhammad Hassaan Ali ◽  
Sana Jahangir
Keyword(s):  
Optical Coherence Tomography ◽  
Tertiary Care ◽  
Posterior Vitreous Detachment ◽  
Age Groups ◽  
P Value ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Hospital Patients ◽  
Vitreomacular Interface

Purpose: To study the frequency of vitreomacular interface abnormalities (VIAs) in diabetic and non-diabeticpatients presenting in a tertiary care hospital.Study Design: Comparative cross-sectional study.Place and Duration of Study: Jinnah hospital, Lahore from May 2013 to June 2016.Methods: The frequency of vitreomacular interface abnormalities (VIAs) was assessed among 278 patients, whopresented in outpatient department of our hospital. Patients were categorized into diabetic and non-diabeticgroups on the basis of hemoglobinHbA1c. Patients with altered macular reflex on slit lamp examination underwentspectral domain (SD) optical coherence tomography (OCT) of macula to determine VIAs.Results: There were 278 patients in the study with mean age 59.7 ± 11.7(range: 40 – 65) years and male tofemale ratio of 1:1.06. Prevalence of VIAs was observed to be higher among diabetic patients than non-diabeticsin all age groups (p-value < 0.05). Overall frequency of different VIAs was found to be 10.7% for epiretinalmembrane, 6.4% for posterior vitreous detachment, 6.1% for macular edema/macular cyst, 4.3% forvitreomacular traction, 1.8% for full thickness macular holes and 0.71% for partial thickness macular holes.Macular edema/macular cystwas the most common. VIA was more commonly observed in diabetic patients(17.2%). Except for ERM, all lesions of VIAs were significantly more prevalent in females as compared to males.Conclusion: VIAs are found in significantly larger number in diabetics compared to non-diabetic patients.Female gender with advancing age is associated with a higher frequency of VIAs.

Healthcare associated infections caused by non-fermenting Gram negative rods (NFGNR): six years of experience of a tertiary hospital

2013 ◽  
Vol 7 (2) ◽  
pp. 06-12
Author(s):  
Zahidul Hasan ◽  
Md. Kamrul Islam ◽  
Arifa Hossain
Keyword(s):  
Blood Stream Infection ◽  
Tertiary Care ◽  
Blood Stream ◽  
Tertiary Hospital ◽  
Healthcare Associated Infections ◽  
Care Hospital ◽  
Gram Negative ◽  
Acinetobacter Spp ◽  
Tract Infections ◽  
Healthcare Associated

Recently non-fermenting Gram negative rods (NFGNR) are playing an important role in healthcare associated infections. This observational study in a tertiary care hospital of Dhaka city conducted during 01August 2007 to 30 June 2013 found that 34.8% isolated organisms from patients with healthcare associated infections were NFGNR. Majority (74.3 %) of these infections were occurring inside critical care areas. Pseudomonas and Acinetobacter together constituted 79.6% of the total NFGNR whereas Burkholderia cephacia complex (15.4%), Stenotrophomonas (4.3%) and Chryseobacterium species (0.7%) combined constituted remaining 20.4%. Out of total NFGNRs, Pseudomonas was responsible for highest number of catheter associated urinary tract infections (55.6%), ventilator associated pneumonia (46.3%), respiratory tract infection (65.8%) and surgical site infection (70.6%). Blood stream infection was predominantly caused by Burkholderia cephacia complex (33.5%) and Acinetobacter spp. (39.5%). Other than colistin most of the organisms were resistant to antibiotics commonly recommended for NFGNR.DOI: http://dx.doi.org/10.3329/bjmm.v7i2.19326 Bangladesh J Med Microbiol 2013; 07(02): 6-12

scholarly journals Acromegaly and the information gap: patient perceptions of the journey from primary to tertiary care

2020 ◽  
Vol 9 (10) ◽  
pp. 971-977
Author(s):  
Hei Yi Vivian Pak ◽  
Andrew Lansdown ◽  
Peter Taylor ◽  
Dafydd Aled Rees ◽  
John Stephen Davies ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Rare Condition ◽  
Structured Interview ◽  
Online Resources ◽  
Care Clinic ◽  
Tertiary Centre ◽  
Information Gap ◽  
Long Term Impact ◽  
A Prospective Study ◽  
Patient Relationships

Objective Acromegaly is a rare condition and there is often a long path to diagnosis for many patients. We sought to explore patient’s perceptions and understanding of acromegaly, to examine the quality of communication and find gaps in the information provided at diagnosis. Design A prospective study using qualitative research methodology and grounded theory. A semi-structured interview was conducted with 18 patients treated for acromegaly in a single tertiary centre and verbatim transcripts were thematically analysed for overarching themes. Results Eighteen patients with acromegaly were interviewed. The mean age of participants was 52 (range 30–72). Four overarching themes emerged; (1) Patients rely on online resources to understand acromegaly in the time between diagnosis and tertiary care clinic; (2) There is not enough support available for patients; (3) Patients have a basic understanding of acromegaly and associated conditions, but the long-term impact is underestimated; and (4) Patients initially felt intimidated by the multidisciplinary team panel, but overall found it useful. Conclusion Acromegalic patients have a strong need for information at the point of initial diagnosis, in particular online resources and interaction with other experienced patients. Wider dissemination of patient educational resources into primary and secondary care settings may improve overall patient satisfaction, treatment adherence and subsequent health care provider–patient relationships.

scholarly journals COLORECTAL CARCINOMA

2011 ◽  
Vol 18 (04) ◽  
pp. 566-570
Author(s):  
AYAZ GUL ◽  
SYED IFTIKHAR ALAM ◽  
RASHID ASLAM ◽  
Waqar Alam
Keyword(s):  
Colorectal Cancer ◽  
Colorectal Carcinoma ◽  
Tertiary Care ◽  
Young Patients ◽  
Age Group ◽  
Surgical Department ◽  
Male Preponderance ◽  
Histologic Types ◽  
Hospital Study

Objective: Colorectal cancer is the second commonest cause of death in the world. Its incidence in young patients is on rise. Objective: To determine the common types of colorectal carcinoma in patients below 40 years of age presenting to tertiary care level hospital. Study Design: Descriptive study Setting: It was carried out at Surgical Department, KTH, Peshawar Period: January 2007 to January 2008. Materials and methods: Total of 50 patients younger than forty years of age with colorectal cancer were included in study for the determination of histologic types. Results: There were 66% males and 34% were females. The commonest affected age group was 31-35 years old having 46% cases. On history 86% patients complained of altered bowel habits and on clinical examination anemia was present in 72% patients. Left and right sided tumors were found in 70% and 30% patients respectively. Adenocarcinoma was the commonest type found in 94% cases followed by lymphoma (4%). Conclusions: The incidence in young age group (≤ 39 years) was highest There was slight male preponderance. Adenocarcinoma was the commonest tumor.

Sign in / Sign up

Export Citation Format

Share Document