scholarly journals Neurosurgical Treatments for Patients with Chronic, Treatment-Refractory Depression: A Retrospective, Consecutive, Case Series Comparison of Anterior Capsulotomy, Anterior Cingulotomy and Vagus Nerve Stimulation

2015 ◽  
Vol 93 (6) ◽  
pp. 387-392 ◽  
Author(s):  
David Christmas ◽  
Keith Matthews
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Chronic Treatment ◽  
Case Series ◽  
Consecutive Case ◽  
Refractory Depression ◽  
Treatment Refractory ◽  
Anterior Capsulotomy

scholarly journals Long term outcome of thermal anterior capsulotomy for chronic, treatment refractory depression

2010 ◽  
Vol 82 (6) ◽  
pp. 594-600 ◽  
Author(s):  
D. Christmas ◽  
M. S. Eljamel ◽  
S. Butler ◽  
H. Hazari ◽  
R. MacVicar ◽  
...  
Keyword(s):  
Chronic Treatment ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Refractory Depression ◽  
Treatment Refractory ◽  
Anterior Capsulotomy

P.2.a.019 Memory and executive functions in patients treated with vagus nerve stimulation for refractory depression

2010 ◽  
Vol 20 ◽  
pp. S344
Author(s):  
V. Desbeaumes ◽  
F. Richer ◽  
E. LaGarde ◽  
S. Patry ◽  
A. Bouthillier ◽  
...  
Keyword(s):  
Executive Functions ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Depression

scholarly journals Tinnitus treatment by vagus nerve stimulation: A systematic review

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247221
Author(s):  
I. Stegeman ◽  
H. M. Velde ◽  
P. A. J. T. Robe ◽  
R. J. Stokroos ◽  
A. L. Smit
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Symptom Severity ◽  
Vagus Nerve Stimulation ◽  
Case Series ◽  
Risk Of Bias ◽  
Cochrane Library ◽  
Validated Questionnaire ◽  
Tinnitus Distress

Background Tinnitus is a phantom sensation of sound, which can have a negative impact on quality of life of those affected. No curative treatments are currently known. Neuromodulation by vagus nerve stimulation has emerged as a new treatment option for tinnitus, though till date the effectiveness remains unclear. Therefore, we aim to review the effect of vagus nerve stimulation on tinnitus distress and tinnitus symptom severity in patients with chronic tinnitus. Methods We searched Pubmed, Embase and the Cochrane Library systematically for RCTs, observational studies and case studies on the effect of VNS treatment for tinnitus on October 29, 2019. Studies including adult patients with subjective tinnitus, comparing transcutaneous or implantable VNS to placebo or no treatment or before and after application of VNS treatment on tinnitus distress and tinnitus symptom severity measured with a validated questionnaire were eligible. The risk of bias was assessed with the appropriate tool for each type of study. Results Our search identified 9 primary studies of which 2 RCTs, 5 cohort studies and 2 case series or reports. 5 studies used transcutaneous VNS treatment and 4 used implanted VNS treatment. 6 studies combined VNS treatment with sound therapy. There was a serious risk of bias in all studies, especially on confounding. Most studies reported a small decrease in tinnitus distress or tinnitus symptom severity. Conclusion Due to methodological limitations and low reporting quality of the included studies, the effect of VNS on tinnitus remains unclear. To draw conclusions for which patient population and to what extent (t)VNS is beneficial in the treatment of tinnitus, a randomised controlled trial should be considered.

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