An Assessment Scale for Social Adaptive Behavior of Children from 3 to 7 Years of Age

Author(s):  
Wang Wenjun ◽  
Fu Gengyao ◽  
Wang Hechun ◽  
Xu Yun
2021 ◽  
pp. 088307382110128
Author(s):  
John M. Schreiber ◽  
Edythe Wiggs ◽  
Rose Cuento ◽  
Gina Norato ◽  
Irene H. Dustin ◽  
...  

We examined safety, tolerability, and efficacy of SGS-742, a γ-aminobutyric acid B (GABA-B) receptor antagonist, in patients with succinic semialdehyde dehydrogenase deficiency. This was a single-center randomized, double-blind crossover phase II clinical trial of SGS-742 versus placebo in patients with succinic semialdehyde dehydrogenase deficiency. Procedures included transcranial magnetic stimulation and the Adaptive Behavior Assessment Scale. Nineteen subjects were consented and enrolled; the mean age was 14.0 ± 7.5 years and 11 (58%) were female. We did not find a significant effect of SGS-742 on the Adaptive Behavior Assessment Scale score, motor threshold, and paired-pulse stimulation. The difference in recruitment curve slopes between treatment groups was 0.003 ( P = .09). There was no significant difference in incidence of adverse effects between drug and placebo arms. SGS-742 failed to produce improved cognition and normalization of cortical excitability as measured by the Adaptive Behavior Assessment Scale and transcranial magnetic stimulation. Our data do not support the current use of SGS-742 in succinic semialdehyde dehydrogenase deficiency. Trial registry number NCT02019667. Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency. https://clinicaltrials.gov/ct2/show/NCT02019667


2020 ◽  
Vol 51 (4) ◽  
pp. 1139-1155
Author(s):  
Jenny M. Burton ◽  
Nancy A. Creaghead ◽  
Noah Silbert ◽  
Allison Breit-Smith ◽  
Amie W. Duncan ◽  
...  

Purpose The purpose of this study was to characterize social communication and structural language of school-age girls with high-functioning autism spectrum disorder (HF-ASD) compared to a matched group of girls who are typically developing (TD). Method Participants were 37 girls between 7;5 and 15;2 (years;months)—18 HF-ASD and 19 TD. Children completed the Test of Pragmatic Language–Second Edition (TOPL-2) and Clinical Evaluation of Language Fundamentals–Fifth Edition. Parents completed the Children's Communication Checklist–2 United States Edition (CCC-2) and Receptive and Expressive Communication subdomains of the Vineland Adaptive Behavior Scales–Second Edition. Results In the area of social communication, girls with HF-ASD earned significantly lower scores and were more often classified as having an impairment on the TOPL-2 and the CCC-2. However, 28% and 33% earned average scores on the TOPL-2 and the CCC-2, respectively. In the area of structural language, no significant differences were found between groups on Clinical Evaluation of Language Fundamentals–Fifth Edition indexes. In contrast, girls with HF-ASD earned significantly lower scores and were more often classified as having an impairment on the Vineland Adaptive Behavior Scales–Second Edition. Sixty-one percent and 83% scored below average on the Receptive and Expressive Communication subdomains, respectively. Conclusions It has been argued that girls with HF-ASD, when compared to boys with HF-ASD, may have advantages for social communication and structural language that mask their impairments. However, when compared to girls who are TD, girls with HF-ASD demonstrated impaired social communication and structural language. Clinicians should include and carefully examine multiple sources of information when assessing girls with HF-ASD.


Pflege ◽  
2015 ◽  
Vol 28 (4) ◽  
pp. 233-243 ◽  
Author(s):  
Gianfranco Zuaboni ◽  
Luciana Degano Kieser ◽  
Bernd Kozel ◽  
Katharina Glavanovits ◽  
Jörg Utschakowski ◽  
...  

Zusammenfassung. Hintergrund: Der Recovery-Ansatz gewinnt in der psychiatrischen Forschung und Praxis zunehmend an Bedeutung. Im englischen Sprachraum ist die praktische Etablierung und wissenschaftliche Auseinandersetzung fortgeschritten. Um die Implementierung des Ansatzes zu unterstützen, sind Einschätzungsinstrumente notwendig. Ein verbreitetes und anerkanntes Instrument ist die Recovery Self Assessment Scale (RSA). Diese besteht aus vier Versionen eines Fragebogens, welche die Perspektiven von Nutzenden, Fachpersonen, Angehörigen und dem Management erfassen. Ziel/Methode: In diesem Artikel werden die Entwicklung des Instrumentes und der Übersetzungsprozess dargestellt. Zwei voneinander unabhängige Arbeitsgruppen verwendeten unterschiedliche Übersetzungsverfahren: Die Arbeitsgruppe aus der Schweiz (AGS) orientierte sich an den ISOR-Prinzipien, die Arbeitsgruppe aus Norddeutschland (AGN) an den Richtlinien des European Social Survey Programme zur Übersetzung von Fragebögen – TRAPD. Die Methoden unterscheiden sich darin, dass die TRAPD Fokusgruppen vorsieht. Die Ergebnisse der Arbeitsgruppen wurden mittels eines Konsensusverfahrens zur RSA-D zusammengeführt. Ergebnisse: Bei der Übersetzung und kulturellen Anpassung der RSA-D wurde die Nähe zum theoretischen Bezugsrahmen der RSA gewahrt und die Übertragbarkeit in den deutschsprachigen Kontext berücksichtigt. Schlussfolgerung: Bevor die RSA-D in der Praxis und Forschung eingesetzt werden kann, sollte in weiterführenden Studien die psychometrische Testung erfolgen.


Crisis ◽  
2011 ◽  
Vol 32 (5) ◽  
pp. 246-253 ◽  
Author(s):  
Gretchen E. Ely ◽  
William R. Nugent ◽  
Julie Cerel ◽  
Mholi Vimbba

Background: The relationship between suicidal thinking and adolescent dating violence has not been previously explored in a sample of adolescent abortion patients. Aims: This paper highlights a study where the relationship between dating violence and severity of suicidal thinking was examined in a sample of 120 young women ages 14–21 seeking to terminate an unintended pregnancy. Methods: The Multidimensional Adolescent Assessment Scale and the Conflict in Adolescent Relationships Scale was used to gather information about psychosocial problems and dating violence so that the relationship between the two problems could be examined, while controlling for the other psychosocial problems. Results: The results suggest that dating violence was related to severity of suicidal thinking, and that the magnitude of this relationship was moderated by the severity of problems with aggression. Conclusions: Specifically, as the severity of participant’s general problems with aggression increased, the magnitude of the relationship between dating violence and severity of suicidal thinking increased. Limitations of the study and implications for practice are discussed.


1990 ◽  
Author(s):  
Judy Howard ◽  
◽  
Leila Beckwith ◽  
Carol Rodning
Keyword(s):  

2010 ◽  
Author(s):  
Rebecca D. Stinson ◽  
Zachary Sussman ◽  
Megan Foley Nicpon ◽  
Allison L. Allmon ◽  
Courtney Cornick ◽  
...  

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