Somatostatin: Biological Actions and Pathophysiology

Biological actions of insulin are differentially regulated by glucose and insulin in primary cultured adipocytes. Chronic ability to increase glycogen synthase activity

Diabetes ◽

10.2337/diabetes.43.1.53 ◽

1994 ◽

Vol 43 (1) ◽

pp. 53-62 ◽

Cited By ~ 3

Author(s):

F. B. Lima ◽

S. Bao ◽

W. T. Garvey

Keyword(s):

Glycogen Synthase ◽

Glycogen Synthase Activity ◽

Biological Actions

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Faculty Opinions recommendation of V1b and CRHR1 receptor heterodimerization mediates synergistic biological actions of vasopressin and CRH.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.714897825.790252982 ◽

2012 ◽

Author(s):

Robert Handa

Keyword(s):

Biological Actions

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HPLC Screening of Bioactives Compounds and Antioxidant Capacity of Different Hypericum Species

Revista de Chimie ◽

10.37358/rc.18.2.6095 ◽

2018 ◽

Vol 69 (2) ◽

pp. 305-309 ◽

Cited By ~ 2

Author(s):

Daniela Gitea ◽

Simona Vicas ◽

Manuel Alexandru Gitea ◽

Sebastian Nemeth ◽

Delia Mirela Tit ◽

...

Keyword(s):

Antioxidant Capacity ◽

Methanol Extract ◽

Antioxidant Properties ◽

Polyphenolic Compounds ◽

The Other ◽

The North ◽

Western Area ◽

North Western ◽

Hypericum Species ◽

Biological Actions

Our study compares the content in polyphenolic compounds and hypericin, in four species of Hypericum - H. perforatum L., H. maculatum Cr., H. hirsutum L., H. tetrapterum Fr. (syn. Hypericumacutum Mnch.) harvested from spontaneous flora in the north-western area of Transylvania, Romania. These species represent an important source of such compounds with different biological actions. After making the extracts, they were subjected to HPLC-SM analysis. The presence of rutoside in the largest amount (462.82 mg %) in the H. perforatum extract was observed, this containing most of the flavonoid heterosides. For the species H. maculatum, the presence in a much higher amount of the hyperoside (976.36 mg %) is characteristic compared to the other species. Quercetol is the best represented of the flavonoid aglycons, its concentration being the highest in H. hirsutum (659.66 mg %). The hypericin content ranges from 0.2171 g % in the H. tetrapterum extract, to 0.0314 g % in the methanol extract of H. maculatum.The highest antioxidant properties measured by FRAP method were recorded in the case of H. perforatum and H. maculatum.

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Natural Cures for Type 1 Diabetes: A Review of Phytochemicals, Biological Actions, and Clinical Potential

Current Medicinal Chemistry ◽

10.2174/0929867311320070006 ◽

2013 ◽

Vol 20 (7) ◽

pp. 899-907

Author(s):

C.L.T. Chang ◽

Yi-Ching Chen ◽

Hui-Ming Chen ◽

Ning-Sun Yang ◽

Wen-Chin Yang

Keyword(s):

Type 1 Diabetes ◽

Clinical Potential ◽

Biological Actions

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A Novel Biological Actions Acquired by Ribonuclease Through Oligomerization

Current Pharmaceutical Biotechnology ◽

10.2174/138920108784567308 ◽

2008 ◽

Vol 9 (3) ◽

pp. 200-209 ◽

Cited By ~ 18

Author(s):

M. Libonati ◽

G. Gotte ◽

F. Vottariello

Keyword(s):

Biological Actions

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Designing of luminescent complexes of europium(III) ion with hydroxyl ketone and nitrogen donor secondary ligands for improving the luminescence performance and biological actions

Inorganica Chimica Acta ◽

10.1016/j.ica.2021.120463 ◽

2021 ◽

pp. 120463

Author(s):

Jyoti Khanagwal ◽

Rajesh Kumar ◽

Pooja Hooda ◽

Poonam ◽

S.P. Khatkar ◽

...

Keyword(s):

Nitrogen Donor ◽

Biological Actions ◽

Luminescence Performance

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Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor

Biochemical Journal ◽

10.1042/bj3180489 ◽

1996 ◽

Vol 318 (2) ◽

pp. 489-495 ◽

Cited By ~ 35

Author(s):

Julia KAROW ◽

Keith R. HUDSON ◽

Mark A. HALL ◽

Ann B. VERNALLIS ◽

Jacky A. TAYLOR ◽

...

Keyword(s):

Biological Effects ◽

Biological Response ◽

Cytoplasmic Domain ◽

Soluble Form ◽

High Affinity ◽

Biological Responses ◽

Interleukin 11 ◽

Biological Actions ◽

In Cells

Interleukin-11 (IL-11) is a polyfunctional cytokine whose biological actions require a specific IL-11 receptor (IL-11R) and the transmembrane transducer gp130. Here we report the production of a soluble form of the murine IL-11R and demonstrate that it interacts with IL-11 ligand with high affinity. The affinity of IL-11 alone for gp130 is below the level of detection, but a complex of IL-11 and soluble IL-11R interacts with gp130 with high affinity. The addition of soluble IL-11R potentiates the effects of exogenous IL-11 in cells that are normally responsive to IL-11. A biological response to IL-11 can be reconstituted in BAF cells transfected with gp130 by addition of IL-11 and soluble IL-11R. These findings show that the cytoplasmic domain of the IL-11R is not required for the biological effects of IL-11 and that a complex of IL-11 and IL-11R mediates signalling by association with gp130.

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