Peripheral Neuropathies in Childhood

2015 ◽  
pp. 60-78
Author(s):  
Robert A. Ouvrier
Keyword(s):  
Peripheral Neuropathies

Focal Peripheral Neuropathies

1999 ◽  
Vol 1 (2) ◽  
pp. 113 ◽  
Author(s):  
John C. Kincaid ◽  
J D Stewart
Keyword(s):  
Peripheral Neuropathies

scholarly journals Combination of serum and CSF neurofilament-light and neuroinflammatory biomarkers to evaluate ALS

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alexandre Brodovitch ◽  
José Boucraut ◽  
Emilien Delmont ◽  
Amandine Parlanti ◽  
Aude-Marie Grapperon ◽  
...  
Keyword(s):  
Serum Levels ◽  
Healthy Controls ◽  
Peripheral Neuropathies ◽  
Neurofilament Light ◽  
Cutoff Value ◽  
Csf Analysis ◽  
Diagnostic Potential ◽  
Ifn Γ ◽  
Als Patients ◽  
Lateral Sclerosis

AbstractThis monocentric prospective study of patient suffering from Amyotrophic lateral sclerosis (ALS) aims to evaluate the prognosis and diagnostic potential of both Neurofilament-Light (Nf-L) and neuroinflammatory biomarkers in serum and CSF. Candidate markers levels were measured using multiplex method in serum of 60 ALS patients, 94 healthy controls of 43 patients suffering from Inflammatory Peripheral Neuropathies (IPN). A comparative CSF analysis was performed for 20 ALS and 17 IPN patients. Among the altered biomarkers, CSF Nf-L level remains the best marker of ALS severity, while serum levels correlate strongly with disease progression. The combination of Nf-L and ICAM-1 concentrations in the CSF and IFN-γ concentration in the serum differentiate ALS patients from IPN patients with improved sensibility and specificity relative to individual biomarkers. A cutoff value of 0.49 for the fitted values of these 3 biomarkers discriminate ALS from IPN patients with a specificity of 100% (78.20–100%) and a sensibility of 85.71% (57.19–98.22%) with an AUC of 0.99 ± 0.01. The measure of Nf-L and neuroinflammatory biomarkers in CSF and serum can be useful biomarkers panel in the differential diagnosis of ALS.

Peripheral Neuropathies

2019 ◽  
Vol 39 (05) ◽  
pp. 517-518
Author(s):  
Michelle Kaku ◽  
Peter Siao
Keyword(s):  
Peripheral Neuropathies

scholarly journals Assessing Autophagy in Sciatic Nerves of a Rat Model that Develops Inflammatory Autoimmune Peripheral Neuropathies

Cells ◽  
2017 ◽  
Vol 6 (3) ◽  
pp. 30 ◽  
Author(s):  
Susana Brun ◽  
Nicolas Schall ◽  
Hélène Jeltsch-David ◽  
Jérôme de Sèze ◽  
Sylviane Muller
Keyword(s):  
Rat Model ◽  
Peripheral Neuropathies ◽  
Sciatic Nerves

Clinical features and molecular genetics of hereditary peripheral neuropathies

2002 ◽  
Vol 249 (12) ◽  
pp. 1629-1650 ◽  
Author(s):  
Gregor Kuhlenb�umer ◽  
Peter Young ◽  
Gert H�nermund ◽  
Bernd Ringelstein ◽  
Florian St�gbauer
Keyword(s):  
Molecular Genetics ◽  
Clinical Features ◽  
Peripheral Neuropathies
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