Use of Nude Mice and Rats for Analyzing Human Cancer Products1

2015 ◽  
pp. 212-219
Author(s):  
Norikazu Tamaoki ◽  
Yoshito Ueyama
Keyword(s):  
Nude Mice ◽  
Human Cancer ◽  
Nude Mice And Rats

Human colonic cancer strains transplantable into nude mice and rats

1985 ◽  
Vol 99 (3) ◽  
pp. 329-331
Author(s):  
N. G. Blokhina ◽  
Yu. N. Solov'ev ◽  
A. V. Ozherel'ev ◽  
E. S. Revazova
Keyword(s):  
Nude Mice ◽  
Colonic Cancer ◽  
Nude Mice And Rats

Toxohormones responsible for cancer cachexia syndrome in nude mice bearing human cancer cell lines

1996 ◽  
Vol 38 (0) ◽  
pp. S48-S52 ◽  
Author(s):  
Naoko Kajimura ◽  
Hideaki Iseki ◽  
R. Tanaka ◽  
Chiharu Ohue ◽  
Kotomi Otsubo ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Nude Mice ◽  
Cancer Cachexia ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Cachexia Syndrome

scholarly journals Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2305 ◽  
Author(s):  
Yu-Cheng Chou ◽  
Meng-Ya Chang ◽  
Hsu-Tung Lee ◽  
Chiung-Chyi Shen ◽  
Tomor Harnod ◽  
...  
Keyword(s):  
Nude Mice ◽  
Human Cancer ◽  
Xenograft Model ◽  
Biological Properties ◽  
Migration And Invasion ◽  
Phenethyl Isothiocyanate ◽  
Human Glioblastoma ◽  
Apoptosis Protein

Phenethyl isothiocyanate (PEITC) from cruciferous vegetables can inhibit the growth of various human cancer cells. In previous studies, we determined that PEITC inhibited the in vitro growth of human glioblastoma GBM 8401 cells by inducing apoptosis, inhibiting migration and invasion, and altering gene expression. Nevertheless, there are no further in vivo reports disclosing whether PEITC can suppress the growth of glioblastoma. Therefore, in this study we investigate the anti-tumor effects of PEITC in a xenograft model of glioblastoma in nude mice. Thirty nude mice were inoculated subcutaneously with GBM 8401 cells. Mice with one palpable tumor were divided randomly into three groups: control, PEITC-10, and PEITC-20 groups treated with 0.1% dimethyl sulfoxide (DMSO), and 10 and 20 μmole PEITC/100 μL PBS daily by oral gavage, respectively. PEITC significantly decreased tumor weights and volumes of GBM 8401 cells in mice, but did not affect the total body weights of mice. PEITC diminished the levels of anti-apoptotic proteins MCL-1 (myeloid cell leukemia 1) and XIAP (X-linked inhibitor of apoptosis protein) in GBM 8401 cells. PEITC enhanced the levels of caspase-3 and Bax in GBM 8401 cells. The growth of glioblastoma can be suppressed by the biological properties of PEITC in vivo. These effects might support further investigations into the potential use of PEITC as an anticancer drug for glioblastoma.

Abstract 2661: Novel albumin-binding maytansinoids inducing long-term partial and complete tumor regressions in several human cancer xenograft models in nude mice

2018 ◽  
Author(s):  
Friederike I. Nollmann ◽  
Patricia Perez Galan ◽  
Javier Garcia Fernandez ◽  
Heidi K. Walter ◽  
Johannes P. Magnusson ◽  
...  
Keyword(s):  
Nude Mice ◽  
Human Cancer ◽  
Albumin Binding ◽  
Xenograft Models ◽  
Complete Tumor

Human Tumors Heterotransplanted in Nude Mice and Rats

Pathobiology ◽  
1984 ◽  
Vol 52 (1-2) ◽  
pp. 76-79 ◽  
Author(s):  
B.C. Giovanella ◽  
J.S. Stehlin ◽  
D. Coil
Keyword(s):  
Nude Mice ◽  
Human Tumors ◽  
Nude Mice And Rats

Strains of human melanoma transplanted into nude mice and rats

1985 ◽  
Vol 99 (4) ◽  
pp. 516-518
Author(s):  
E. S. Revazova ◽  
Yu. N. Solov'ev ◽  
L. V. Litvinova ◽  
D. D. Kochetkova
Keyword(s):  
Nude Mice ◽  
Human Melanoma ◽  
Nude Mice And Rats

Anticancer exffect of 9-nitrocamptothecin liposome aerosol on human cancer xenografts in nude mice

1999 ◽  
Vol 44 (3) ◽  
pp. 177-186 ◽  
Author(s):  
Vernon Knight ◽  
Nadezhda V. Koshkina ◽  
J. Clifford Waldrep ◽  
Beppino C. Giovanella ◽  
Brain E. Gilbert
Keyword(s):  
Nude Mice ◽  
Human Cancer

Researches on the anti-autologous tumor effects of human cancer-killing cells in nude mice

1992 ◽  
Vol 4 (4) ◽  
pp. 30-32
Author(s):  
Binxue Zhang ◽  
Yao Tang ◽  
Jie Zheng ◽  
Cheng Yin ◽  
Jieliang Wang ◽  
...  
Keyword(s):  
Nude Mice ◽  
Human Cancer ◽  
Autologous Tumor
Sign in / Sign up

Export Citation Format

Share Document