Strains of human melanoma transplanted into nude mice and rats

1985 ◽  
Vol 99 (4) ◽  
pp. 516-518
Author(s):  
E. S. Revazova ◽  
Yu. N. Solov'ev ◽  
L. V. Litvinova ◽  
D. D. Kochetkova
Keyword(s):  
Nude Mice ◽  
Human Melanoma ◽  
Nude Mice And Rats

Sequential detection of mRNA for the chemokine IL-8 and macrophages (F4/80) in human melanoma

1995 ◽  
Vol 53 ◽  
pp. 1008-1009
Author(s):  
C.D. Bucana ◽  
R. Sanchez ◽  
R. Singh ◽  
I.J. Fidler
Keyword(s):  
Tumor Cells ◽  
Nude Mice ◽  
Constitutive Expression ◽  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Angiogenic Factor ◽  
Infiltrating Cells ◽  
Immunoperoxidase Assay ◽  
Multifunctional Cytokine

The purpose of this study was to demonstrate by ISH the presence of IL-8 mRNA, and by immunohistochemistry (IHC) the presence of the chemokine IL-8 and the distribution of infiltrating macrophages in subcutaneous melanomas in the same tumor. IL-8 is a multifunctional cytokine produced by melanoma cells, activated macrophages and monocytes and it has been shown to be a growth and angiogenic factor for tumor cells. More recently it was shown that constitutive expression of IL-8 correlated directly with metastatic potential of human melanoma cells in nude mice. IL-8 content of a solid tumor as determined by Western blot analysis does not take into account the contribution of macrophages. Previous studies showed that murine tumors contain many infiltrating cells interspersed among tumor cells whereas human tumors growing in nude mice exhibit macrophages at the periphery or between tumor islands. In this study we demonstrate the expression of IL-8 and the distribution of macrophages by immunoperoxidase assay and IL-8 mRNA by ISH.

Selective growth of human melanoma cells in the brain parenchyma of nude mice

1996 ◽  
Vol 6 (5) ◽  
pp. 363-371 ◽  
Author(s):  
T Fujimaki ◽  
J E Price ◽  
D Fan ◽  
C D Bucana ◽  
K Itoh ◽  
...  
Keyword(s):  
Nude Mice ◽  
Melanoma Cells ◽  
Brain Parenchyma ◽  
Human Melanoma ◽  
Selective Growth ◽  
Human Melanoma Cells ◽  
The Brain

Human colonic cancer strains transplantable into nude mice and rats

1985 ◽  
Vol 99 (3) ◽  
pp. 329-331
Author(s):  
N. G. Blokhina ◽  
Yu. N. Solov'ev ◽  
A. V. Ozherel'ev ◽  
E. S. Revazova
Keyword(s):  
Nude Mice ◽  
Colonic Cancer ◽  
Nude Mice And Rats

scholarly journals The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice

1999 ◽  
Vol 79 (7-8) ◽  
pp. 1025-1031 ◽  
Author(s):  
U Mrowietz ◽  
U Schwenk ◽  
S Maune ◽  
J Bartels ◽  
M Küpper ◽  
...  
Keyword(s):  
Nude Mice ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells ◽  
Tumour Formation

Human Tumors Heterotransplanted in Nude Mice and Rats

Pathobiology ◽  
1984 ◽  
Vol 52 (1-2) ◽  
pp. 76-79 ◽  
Author(s):  
B.C. Giovanella ◽  
J.S. Stehlin ◽  
D. Coil
Keyword(s):  
Nude Mice ◽  
Human Tumors ◽  
Nude Mice And Rats

Interactions with host macrophages and ability of human melanoma cell lines to grow in nude mice

1986 ◽  
Vol 38 (3) ◽  
pp. 419-424 ◽  
Author(s):  
Abdeljalil Benomar ◽  
Denis Gerlier ◽  
Jean-Fran??ois Doré
Keyword(s):  
Cell Lines ◽  
Melanoma Cell ◽  
Nude Mice ◽  
Human Melanoma ◽  
Human Melanoma Cell ◽  
Melanoma Cell Lines
Sign in / Sign up

Export Citation Format

Share Document