Strategies to Produce Virus-Safe Blood Derivatives

2015 ◽  
pp. 23-33 ◽  
Author(s):  
N. Heimburger ◽  
H. E. Karges
Keyword(s):  
Safe Blood

Blood Pressure and Intraventricular Hemorrhage in Premature Infants

PEDIATRICS ◽  
1990 ◽  
Vol 86 (6) ◽  
pp. 1006-1006
Author(s):  
V. F. PUCCIO ◽  
M. SOLIANI
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Critically Ill ◽  
High Blood Pressure ◽  
Intracranial Hemorrhage ◽  
Premature Infants ◽  
Intraventricular Hemorrhage ◽  
Mean Blood Pressure ◽  
Central Topic ◽  
Safe Blood

To the Editor.— We have read with great interest the recently published article by Perry et al.1 The need to define "safe" blood pressure levels in the critically ill premature infants is a central topic in the prevention of intracranial hemorrhage. However, in Perry's paper maximum systolic blood pressure and maximum mean blood pressure values are much higher than those reported by previously published articles.2-4 High blood pressure values were reported by Lou and Friis-Hansen5 in nine newborns.

scholarly journals Retrospective analysis of the most common cause of rejection of donors for blood donation

2021 ◽  
Vol 8 (3) ◽  
pp. 444
Author(s):  
Garima Vijayvergiya ◽  
Parag Fulzele ◽  
Naveen Vairyamoorthy
Keyword(s):  
Blood Pressure ◽  
Blood Donor ◽  
Blood Donation ◽  
Tertiary Care ◽  
Geographical Area ◽  
Rejection Rate ◽  
Developed Countries ◽  
Care Hospital ◽  
Systemic Examination ◽  
Safe Blood

Background: A significant imbalance in access to safe blood is seen between the developing and developed countries. Donor selection has a pivotal role in preventing transfusion related complications and provide safety to the recipients. In this study, we aimed to find out rate and causes of blood donor rejection in our hospital.  Methods: A retrospective study conducted in a tertiary care hospital involving both the voluntary and replacement donors during the period September 2017 to December 2018. We included all those donors who were considered unfit for blood donation. All those who came for blood donation at our hospital were asked to fill up an enrolment form for a blood donor. A general and systemic examination were done. We calculated the rejection rate, listed the reasons for donor rejection, and analyzed the data.Results: Among 150 rejected blood donors, most were males [129 (86%)], and the rest were females [21 (14%)]. The rejection rate in our study was 3.29%. We found that the rejection rate of donors was different among voluntary and replacement donors. It showed that the most common reason for the temporary rejection of blood donation was low hemoglobin level, followed by abnormal blood pressure.  Conclusions: A vast majority of donors were rejected temporarily [132 (88%)], while the rest of them were rejected permanently [18 (12%)]. Low Hb in females and abnormal blood pressure in males were the commonest causes of blood donor rejection. Many factors affect the similarities and variations between the most typical causes of blood donor rejection, such as geographical area, cultural, socio-economic, and educational factors.  

scholarly journals Haemovigilance: New approach for safe Blood transfusion

2019 ◽  
Vol 7 (4) ◽  
pp. 1-7
Author(s):  
Sravya Sree ◽  
Pasikhanti Shailaja
Keyword(s):  
Blood Transfusion ◽  
Adverse Reactions ◽  
Uttar Pradesh ◽  
Primary Objective ◽  
Family Welfare ◽  
Blood Collection ◽  
Blood Products ◽  
Preventive Actions ◽  
Potential Risks ◽  
Safe Blood

Haemovigilance is an urgent need of the country to identify and prevent occurrence or recurrence of transfusion related adverse reactions, thereby to increase the safety and quality of blood transfusion and blood products administration. Haemovigilance is an organised scheme of monitoring, identifying, reporting, investigating and analysing adverse events and reactions pertinent to transfusion and manufacturing blood products. Thus the information collected will facilitate corrective and preventive actions to minimise the potential risks associated with blood collection, processing and transfusion to patients. Indian Pharmacopoeia Commission has started a Haemovigilance Program of India (HvPI) in 2012 under its Pharmacovigilance Program of India (PvPI) in collaboration with National Institute of Biologicals (NIB), Noida, Uttar Pradesh, under Ministry of Health and Family welfare, Government of India with a primary objective to track adverse reactions/events and incidences associated with blood transfusion and blood product administration. The main objective of this article is to brief (s) about the system which monitors each and every step of transfusion reaction.

EVALUATION OF REASONS OF PRE-DONATION BLOOD DONOR DEFERRAL IN A TERTIARY CARE HOSPITALAT DHAKA

2021 ◽  
pp. 69-71
Author(s):  
Daanish Arefin Biswas ◽  
Tamanna Afroz ◽  
Md. Wasim ◽  
Bepasha Naznin ◽  
Hasiba Akter Bhuiyan
Keyword(s):  
Blood Donors ◽  
Tertiary Care ◽  
Standard Operating Procedure ◽  
Care Hospital ◽  
Male Population ◽  
Human Errors ◽  
Medical College ◽  
Safe Blood ◽  
Donor Deferral ◽  
Or History

Background: Our aim is to evaluate reasons of donor deferral in tertiary care hospital to nd new disease distribution, any areas of negligence in part of donor or history taking physicians and human errors which could be easily correctable and benecial for donors to remain healthy and provide safe blood. Methodology: This is a retrospective analytic study carried out during the period of January to December 2015 at Department of Transfusion Medicine, Sir Salimullah Medical College and Mitford Hospital. After preliminary registration, each donor was either selected or deferred by medical ofcers. The donor selection and deferral criteria were according to the standard operating procedure. Detailed information of reason of deferral was recorded. Results:Among 10056 registered donors, 9453 (94.004%) were eligible for donation and 603 (5.996%) blood donors were deferred due to various reasons. Male donors were 7526 (74.84%) more than female 2530 (25.16%). Females (60.03%) were found to have higher deferral rate than male population (39.97%). Low hemoglobin was found to be leading cause constituting 17.58% followed by hypertension 15.26%, medications 12.11% and underweight 11.28%. Conclusion: Deferral may discourage the donor for subsequent donations, especially young rst time donors. Deferred donors should be properly counseled and educated for probable future donations. By knowing the causes of deferral we can take further steps to prevent those causes and can preserve precious blood and blood components.

CMV-Safe Blood Products

2013 ◽  
pp. 279-282
Author(s):  
Jennifer L. Garbaini ◽  
Christopher D. Hillyer
Keyword(s):  
Blood Products ◽  
Safe Blood

7. Treatment and prevention dilemmas

2016 ◽  
pp. 95-107
Author(s):  
Alan Whiteside
Keyword(s):  
Behaviour Change ◽  
Cost Effective ◽  
Community Mobilization ◽  
Infected People ◽  
Social Interventions ◽  
Major Threat ◽  
Treatment And Prevention ◽  
Current State ◽  
Safe Blood ◽  
Public Health Programmes

AIDS is still a major threat. ‘Treatment and prevention dilemmas’ shows that prevention and public health programmes are the most cost-effective way to health. HIV infection is preventable through biomedical strategies, such as ensuring safe blood and blood products by screening donors and testing donations; social interventions advising behaviour change, such as using condoms, having fewer partners, and practicing monogamy or abstinence; and—crucial to behaviour change—community mobilization and leadership. AIDS treatment developments are described along with the current state of antiretroviral therapy. Looking ahead, prevention remains the priority—while HIV infected people can live normal, productive lives, it is challenging and expensive.

scholarly journals Hazards of Bacterial Contamination of Blood Products

1993 ◽  
Vol 21 (1) ◽  
pp. 20-23 ◽  
Author(s):  
T. Gottlieb
Keyword(s):  
Bacterial Contamination ◽  
Skin Surface ◽  
Blood Products ◽  
Gram Positive ◽  
Viral Pathogens ◽  
Gram Negative ◽  
Safe Blood ◽  
The Third World ◽  
Collection Practice ◽  
Transfusion Reactions

Post-transfusion bacterial sepsis is infrequent. It is, however, associated with a high mortality due to septic shock. This reflects the release of endotoxin from gram negative bacteria. Lesser transfusion reactions are usually under-reported. These are frequently caused by gram positive bacteria. Gram positive species such as staphylococci and other skin surface organisms may be cultured from platelets stored at room temperature. Typically, gram negative “psychrophyllic” species which survive storage at 4°C are cultured from stored refrigerated blood implicated in transfusion reactions. These include Yersinia enterocolitica, Pseudomonas fluorescens etc. Bacterial contamination of the blood supply can occur via an endogenous or an exogenous source. Endogenous donor bacteraemia due to Y.enterocolitica may be asymptomatic or may follow an episode of gastroenteritis. Exogenous infections occur through some defect in the usual collection practice. Transfusion-acquired syphilis is now extremely uncommon. In the third world, beside the need for effective screening for viral pathogens, infections with protozoa, in particular plasmodia, trypanosoma and leishmania remain a major obstacle to ensuring safe blood supplies. Prevention of transfusion reactions demands rigorous attention to details of collection, storage, reissuing and infusion of blood products, as well as prompt treatment, testing and reporting of suspected reactions.

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