Beta-2-Microglobulin-Related Amyloidosis in Long-Term Hemodialysis Patients: Possible Pathogenetic Mechanisms

Author(s):  
T. Dr�eke ◽  
J. Zingraff
2001 ◽  
Vol 19 (3) ◽  
pp. 301-307 ◽  
Author(s):  
Chun-Liang Lin ◽  
Chih-Wei Yang ◽  
Chin-Chen Chiang ◽  
Ching-Tung Chang ◽  
Chiu-Ching Huang

1993 ◽  
Vol 39 (2) ◽  
pp. 277-280 ◽  
Author(s):  
M Mogi ◽  
M Harada ◽  
K Kojima ◽  
T Adachi ◽  
S Nakamura

Abstract We examined the suitability of high-performance immunoaffinity chromatography (HPIAC) for removing beta 2-microglobulin (beta 2-MG) from plasma of patients (n = 26) undergoing long-term hemodialysis. We used immobilized antibody to beta 2-MG to prepare an immunoaffinity column with a 0.5-mL bed volume. Plasma samples of 0.5 mL were chromatographed at a flow rate of 0.5 mL/min and pressures < 7 kg/cm2. Although only a small amount of beta 2-MG can be removed with a conventional dialyzer, 92.1% +/- 0.4% of the globulin could be removed by HPIAC. The column could be reused after acid elution. After 50 cycles the efficiency of beta 2-MG trapping was 73% of the original efficiency.


1991 ◽  
pp. 801-804 ◽  
Author(s):  
G. Merlini ◽  
D. Limido ◽  
V. Bellotti ◽  
E. Bucciarelli ◽  
P. Berretta ◽  
...  

2002 ◽  
Vol 20 (2) ◽  
pp. 161-166 ◽  
Author(s):  
Thomas M. Pickett ◽  
Alastair Cruickshank ◽  
Roger N. Greenwood ◽  
David Taube ◽  
Andrew Davenport ◽  
...  

1989 ◽  
Vol 9 (3) ◽  
pp. 177-183 ◽  
Author(s):  
William J. Stone ◽  
Raymond M. Hakim

1987 ◽  
Vol 40 (10) ◽  
pp. 1247-1251 ◽  
Author(s):  
J M Theaker ◽  
A E Raine ◽  
A J Rainey ◽  
A Heryet ◽  
A Clark ◽  
...  

Nephron ◽  
1989 ◽  
Vol 53 (1) ◽  
pp. 73-75 ◽  
Author(s):  
J. Floege ◽  
A. Brandis ◽  
B. Nonnast-Daniel ◽  
M. Westhoff-Bleck ◽  
G. Tiedow ◽  
...  

1991 ◽  
Vol 67 (3) ◽  
pp. 188-193 ◽  
Author(s):  
J W Mulder ◽  
P Krijnen ◽  
R A Coutinho ◽  
M Bakker ◽  
J Goudsmit ◽  
...  

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