Environmental Factors in Inflammatory Bowel Disease1

2015 ◽  
pp. 158-175 ◽  
Author(s):  
T. Gilat ◽  
M. J. S. Langman ◽  
P. Rozen
Keyword(s):  
Environmental Factors ◽  
Inflammatory Bowel

scholarly journals Modifiable Environmental Factors in Inflammatory Bowel Disease

2017 ◽  
Vol 19 (5) ◽  
Author(s):  
Kristin E. Burke ◽  
Christine Boumitri ◽  
Ashwin N. Ananthakrishnan
Keyword(s):  
Inflammatory Bowel Disease ◽  
Environmental Factors ◽  
Bowel Disease ◽  
Inflammatory Bowel

scholarly journals Environmental factors associated with biological use and surgery in inflammatory bowel disease

2020 ◽  
Author(s):  
Kimberley W J Sloot ◽  
Paul Geertsema ◽  
Hanneke C Rijkmans ◽  
Michiel D Voskuil ◽  
Hendrik M Dullemen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Environmental Factors ◽  
Bowel Disease ◽  
Factors Associated ◽  
Inflammatory Bowel

scholarly journals Identification of Environmental Risk Factors Associated With the Development of Inflammatory Bowel Disease

2020 ◽  
Vol 14 (12) ◽  
pp. 1662-1671
Author(s):  
Kimberley W J van der Sloot ◽  
Rinse K Weersma ◽  
Behrooz Z Alizadeh ◽  
Gerard Dijkstra
Keyword(s):  
Inflammatory Bowel Disease ◽  
Environmental Factors ◽  
Bowel Disease ◽  
Multiple Testing ◽  
Stressful Life Events ◽  
Population Based ◽  
Factors Associated ◽  
Disease Aetiology ◽  
Inflammatory Bowel ◽  
Genetic And Environmental Factors

Abstract Background and Aims Multiple genetic and environmental factors are involved in the aetiology of inflammatory bowel disease [IBD] including Crohn’s disease [CD] and ulcerative colitis [UC], but data on these exposome factors are difficult to identify. Several exposome factors such as smoking have been shown to be involved; as for other environmental factors, eg stress, results have been conflicting. Methods We performed a case-control study including 674 IBD patients of the 1000IBD cohort, frequency-matched based on sex and age with 1348 controls from the population-based Lifelines Cohort Study. Exposome data were obtained using the validated Groningen IBD Environmental Questionnaire [GIEQ], capturing exposome factors through different stages of life using 844 items, of which 454 were applicable to study the role of 93 exposome factors in disease aetiology. Logistic regression [LR] modelling with Bonferroni correction for multiple testing was applied to estimate the multivariable-adjusted effect of each exposome factor. Results For IBD, we identified four novel factors: stressful life events (CD odds ratio [OR] 2.61/UC OR 2.92), high perceived stress [2.29/2.67], alcohol use [0.40/0.43], and bronchial hyper-reactivity [3.04/2.36]. Four novel factors were associated with only CD: prenatal smoke exposure [1.89], having a bed partner [0.53], allergies [2.66], and cow’s milk hypersensitivity [5.87]; and two solely with UC: carpet flooring [0.57] and neuroticism [1.32]. Nine factors were replicated. Conclusions In this study we identified 10 novel, and replicated nine previously reported, exposome factors associated with IBD. Identifying these factors is important for both understanding disease aetiology and future prevention strategies to decrease the development of IBD in genetically susceptible persons.

scholarly journals Environmental factors in inflammatory bowel disease: A case-control study based on a Danish inception cohort

2011 ◽  
Vol 5 (6) ◽  
pp. 577-584 ◽  
Author(s):  
Tanja Stenbaek Hansen ◽  
Tine Jess ◽  
Ida Vind ◽  
Margarita Elkjaer ◽  
Malene Fey Nielsen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Environmental Factors ◽  
Bowel Disease ◽  
Case Control Study ◽  
Case Control ◽  
Inception Cohort ◽  
Inflammatory Bowel ◽  
Control Study

scholarly journals Influence of smoking and other environmental factors in inflammatory bowel disease activity: what do our patients think?

Gut ◽  
2011 ◽  
Vol 60 (Suppl 1) ◽  
pp. A210-A210
Author(s):  
M. Thole ◽  
G. Erian ◽  
F. Jaboli ◽  
K. Greveson ◽  
O. Epstein ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Environmental Factors ◽  
Disease Activity ◽  
Bowel Disease ◽  
Inflammatory Bowel

Inflammatory bowel disease: the role of environmental factors

2004 ◽  
Vol 3 (5) ◽  
pp. 394-400 ◽  
Author(s):  
Silvio Danese ◽  
Miquel Sans ◽  
Claudio Fiocchi
Keyword(s):  
Inflammatory Bowel Disease ◽  
Environmental Factors ◽  
Bowel Disease ◽  
Inflammatory Bowel
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