Evidence for a Central Serotonergic Projection to the Cerebral Resistance Vessels: Possible Functional Implications

2015 ◽  
pp. 213-224 ◽  
Author(s):  
L. Edvinsson ◽  
E. T. MacKenzie ◽  
B. Scatton
Keyword(s):  
Resistance Vessels ◽  
Functional Implications ◽  
Cerebral Resistance

Effects of 5-hydroxytryptamine and adenosine on the canine isolated cerebral resistance vessels

2011 ◽  
Vol 7 (01) ◽  
pp. 34-40 ◽  
Author(s):  
Youji Ohigashi ◽  
Y. Kawai ◽  
J. Wang ◽  
T. Ohhashi
Keyword(s):  
Resistance Vessels ◽  
Cerebral Resistance

Hyperthermia increases cerebral metabolic rate and blood flow in neonatal pigs

1988 ◽  
Vol 255 (2) ◽  
pp. H343-H346 ◽  
Author(s):  
D. W. Busija ◽  
C. W. Leffler ◽  
M. Pourcyrous
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Metabolic Rate ◽  
Intravenous Injection ◽  
Neonatal Pigs ◽  
Cerebral Metabolic Rate ◽  
Resistance Vessels ◽  
Newborn Pigs ◽  
Cerebral Resistance

We examined effects of hyperthermia on cerebral metabolic rate for oxygen (CMRO2) and cerebral blood flow (CBF) in anesthetized, newborn pigs (2–5 days old). CBF and CMRO2 were measured during normothermia (38 degrees C) and during hyperthermia induced by body heating (42 degrees C). During normothermia, total CBF was 32 +/- 3 ml.min-1.100 g-1 (n = 9), and CMRO2 was 1.34 +/- 0.08 ml O2.100 g-1.min-1 (n = 7). During hyperthermia, total CBF increased by 97 +/- 23% and CMRO2 by 65 +/- 24%. We also examined whether cerebral resistance vessels were responsive under these conditions. During hyperthermia, total CBF was 63 +/- 6 ml.min-1.100 g-1, and CMRO2 was 2.13 +/- 0.27 ml O2.100 g-1.min-1. During sustained hyperthermia, intravenous injection of 5 mg/kg of indomethacin decreased total CBF by 45 +/- 7% (n = 9), and CMRO2 fell by 55 +/- 10% (n = 5). We conclude that 1) hyperthermia increases CBF and CMRO2, and 2) the dilated cerebrovascular bed during hyperthermia still is responsive to a constrictor stimulus.

SODIUM NITROPRUSSIDE DOES NOT DILATE CEREBRAL RESISTANCE VESSELS DURING HYPOTHERMIC CARDIOPULMONARY BYPASS

1990 ◽  
Vol 70 (Supplement) ◽  
pp. S327
Author(s):  
A T Rogers ◽  
D S Prough ◽  
S A Mills ◽  
D A Stump ◽  
J Phipps ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Sodium Nitroprusside ◽  
Hypothermic Cardiopulmonary Bypass ◽  
Resistance Vessels ◽  
Cerebral Resistance

Sodium Nitroprusside Infusion Does Not Dilate Cerebral Resistance Vessels during Hypothermic Cardiopulmonary Bypass

1991 ◽  
Vol 74 (5) ◽  
pp. 820-826 ◽  
Author(s):  
Anne T. Rogers ◽  
Donald S. Prough ◽  
Glenn P. Gravlee ◽  
Raymond C. Roy ◽  
Stephen A. Mills ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Sodium Nitroprusside ◽  
Hypothermic Cardiopulmonary Bypass ◽  
Resistance Vessels ◽  
Cerebral Resistance ◽  
Nitroprusside Infusion

scholarly journals Cerebral Blood Flow Autoregulation in Acute Intracranial Hypertension

1994 ◽  
Vol 14 (3) ◽  
pp. 519-525 ◽  
Author(s):  
John Hauerberg ◽  
Marianne Juhler
Keyword(s):  
Intracranial Hypertension ◽  
Ringer Solution ◽  
Significant Shift ◽  
Arterial Blood ◽  
Resistance Vessels ◽  
Acute Elevation ◽  
Series Of Experiments ◽  
Low Levels ◽  
Cerebral Resistance ◽  
Increased Icp

The present series of experiments was carried out to investigate CBF autoregulation during fixed levels of acute increased intracranial pressure (ICP). Three groups of six rats each, one with normal ICP (8 mm Hg), one with moderately increased ICP (30 mm Hg), and one with severely increased ICP (50 mm Hg), were investigated. ICP was maintained by continuous infusion of lactated Ringer solution into the cisterna magna. Cerebral perfusion pressure (CPP), calculated as mean arterial blood pressure – ICP, was increased by intravenously infused norepinephrine and decreased by controlled bleeding. In all groups the corresponding autoregulation curve included a plateau where CBF was independent of changes in CPP, demonstrating intact autoregulation. However, a significant shift of the lower limit of autoregulation (LL) toward lower CPP levels during severe intracranial hypertension was observed (p < 0.006). In the controls the LL was found at CPP = 73 ±6 mm Hg, in moderately increased ICP the LL was 59 ± 4 mm Hg, and in severely increased ICP the LL was 51 ±4 mm Hg. These results indicate that an acute elevation of ICP activates a reserve capacity of cerebral resistance vessels that dilate further below the normal physiological LL to maintain CBF at low levels of CPP.

Valsalva maneuver suggests increased rigidity of cerebral resistance vessels in familial dysautonomia

2002 ◽  
Vol 12 (5) ◽  
pp. 385-392 ◽  
Author(s):  
M. J. Hilz ◽  
F. B. Axelrod ◽  
M. Steingrueber ◽  
B. Stemper
Keyword(s):  
Valsalva Maneuver ◽  
Familial Dysautonomia ◽  
Resistance Vessels ◽  
Cerebral Resistance

Permeability of Endometrial Blood Vessels to Exogenous Horse Radish Peroxidase in Mice. Electron Microscope Study

1973 ◽  
Vol 31 ◽  
pp. 562-563
Author(s):  
M.C. Castillo-Jessen ◽  
A. González-Angulo
Keyword(s):  
Electron Microscopy ◽  
Blood Vessels ◽  
Electron Microscope Study ◽  
Ultrastructural Level ◽  
Low Molecular Weight ◽  
Horse Radish Peroxidase ◽  
Intravascular Injection ◽  
Normal Morphology ◽  
Functional Implications ◽  
Low Molecular Weight Proteins

Information regarding the normal morphology of uterine blood vessels at ultrastructural level in mammals is scarce Electron microscopy studies dealing with endometrial vasculature despite the functional implications due to hormone priming are not available. Light microscopy observations with combined injection of dyes and microradiography along with histochemical studies does not enable us to know the detailed fine structure of the possible various types of blood vessels in this tissue. The present work has been designed to characterize the blood vessels of endometrium of mice as well as the behavior of the endothelium to injection of low molecular weight proteins during the normal estrous cycle in this animal. One hundred and forty female albino mice were sacrificed after intravascular injection of horse radish peroxidase (HRP) at 30 seconds, 5, 15, 30 and 60 minutes.

Intraindividual Variability and Stability of Affect and Well-Being

GeroPsych ◽  
2013 ◽  
Vol 26 (3) ◽  
pp. 185-199 ◽  
Author(s):  
Christina Röcke ◽  
Annette Brose
Keyword(s):  
Age Differences ◽  
Well Being ◽  
Subjective Well Being ◽  
Emotional Experiences ◽  
Short Term ◽  
Regulatory Processes ◽  
Functional Implications ◽  
Methodological Approaches ◽  
Underlying Processes

Whereas subjective well-being remains relatively stable across adulthood, emotional experiences show remarkable short-term variability, with younger and older adults differing in both amount and correlates. Repeatedly assessed affect data captures both the dynamics and stability as well as stabilization that may indicate emotion-regulatory processes. The article reviews (1) research approaches to intraindividual affect variability, (2) functional implications of affect variability, and (3) age differences in affect variability. Based on this review, we discuss how the broader literature on emotional aging can be better integrated with theories and concepts of intraindividual affect variability by using appropriate methodological approaches. Finally, we show how a better understanding of affect variability and its underlying processes could contribute to the long-term stabilization of well-being in old age.

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