Shock Lung and Alterations of the Alveolar Lining. An Experimental Trial

Author(s):  
M. Bruni
2001 ◽  
Vol 66 (549) ◽  
pp. 169-176 ◽  
Author(s):  
Koichi WADA ◽  
Shin-ya NISHIMURA ◽  
Kazuya TAKAHASHI ◽  
Bo ZHOU ◽  
Takashi TAKAHASHI

Author(s):  
Kyoung Ok Park ◽  
Myung Sun Lee ◽  
Sang Hyuk Jung ◽  
In Seok Kim ◽  
Young A Oh

2019 ◽  
Vol 85 ◽  
pp. 16-21 ◽  
Author(s):  
Tricya Nunes Vieira Bueloni ◽  
Daniel Marchi ◽  
Camille Caetano ◽  
Ricardo de Souza Cavalcante ◽  
Marcela Lara Mendes Amaral ◽  
...  

1979 ◽  
Author(s):  
C.N. McCollum

Intravascular platelet aggregates (IPA) have as yet avoided detection in shocked patients hence their role in the aetiology of “shock lung” remains controversial. Screen filtration pressure (SFP) has only been shown to measure aggregates in vitro.A modified screen filtration technique was evaluated in 43 surgical patients. The characteristics (height,slope) of the pressure wave were compared with the number of aggregates seen to occlude filter pores on scanning electron microscopy (SEM). In 80 estimations on femoral vein blood the slope of the SFP curve was utilised improving SFP/ SEM correlation to r= .93. These aggregates arise in vivo as they were rarely detected in blood from the arm and IPA levels in femoral blood were not influenced by EDTA priming of the syringe. In 36 preoperative estimations mean SFP slope was identical to that in 14 patients after minor surgery (1.5 ± SD 1.6). After major surgery in 29 patients this value was elevated at 7.1 ± 6.1 (P<.001). Seventeen of these patients with SFP slope greater than 5 suffered a mean fall in arterial P2 at 5 days post operation of 1.85 KPa (13.9 mm Hg) which was significantly greater than that in the other major cases (0.85 KPa, 6.4 mm Hg)(P <.05). SFP also correlated closely with the fall in platelet count on day 1 post operation (r= .82, P< .001).Intravascular platelet aggregates arise in the veins of the lower limb immediately after major surgery. They can be measured by the screen filtration technique described and may be related to pulmonary dysfunction.


1976 ◽  
Vol 51 (6) ◽  
pp. 537-543 ◽  
Author(s):  
Suzanne Oparil ◽  
J. Low ◽  
T. J. Koerner

1. A specific method is described for the measurement of angiotensin I converting enzyme activity in plasma with 125I-labelled angiotensin I used as substrate. 2. Converting enzyme activity in plasma from fifteen normal subjects, eleven patients with sarcoidosis, twelve patients with chronic obstructive pulmonary disease and three patients with shock lung was assayed by this technique. 3. Patients with sarcoidosis had increased plasma converting enzyme activity whether or not they were receiving steroid therapy. 4. Patients with chronic obstructive pulmonary disease and shock lung had decreased plasma converting enzyme activity, but extent of conversion did not correlate with the severity of the lung disease. 5. Converting enzyme activity in normal plasma could be completely inhibited by addition of exogenous angiotensin I in 0·5–2·5 × 107 times physiological concentration. Twice as much exogenous angiotensin I was needed to inhibit conversion completely in plasma from patients with sarcoidosis; one tenth as much in chronic obstructive pulmonary disease. These results indicate that plasma has a high capacity for angiotensin I conversion even in patients with pulmonary parenchymal disease. 6. Results suggest that plasma converting enzyme activity may be a reflection of pulmonary conversion and can be altered by pulmonary disease. 7. Measurement of plasma converting enzyme activity may be useful in studies designed to characterize the regulatory role of converting enzyme in the renin—angiotensin system and in cardiovascular homeostasis.


1979 ◽  
Vol 7 (3) ◽  
pp. 117-124 ◽  
Author(s):  
WILLIAM C. SHOEMAKER ◽  
CARL J. HAUSER
Keyword(s):  

1990 ◽  
Vol 19 (1) ◽  
pp. 14-19 ◽  
Author(s):  
DEBORA J. OSUNA ◽  
DAVID J. DeYOUNG ◽  
RICHARD L. WALKER

2009 ◽  
Vol 66 (7) ◽  
pp. 1515-1519 ◽  
Author(s):  
Suchana Chavanich ◽  
Voranop Viyakarn ◽  
Thepsuda Loyjiw ◽  
Priyapat Pattaratamrong ◽  
Anchalee Chankong

Abstract Chavanich, S., Viyakarn, V., Loyjiw, T., Pattaratamrong, P., and Chankong, A. 2009. Mass bleaching of soft coral, Sarcophyton spp. in Thailand and the role of temperature and salinity stress. – ICES Journal of Marine Science, 66: 1515–1519. From June to October 2006 and 2007, mass bleaching of the soft coral, Sarcophyton spp., occurred for the first time in the upper Gulf of Thailand. Approximately 90% of the populations experienced extensive bleaching, and almost 95% of colonies were affected. Field observations also revealed that fragmentation of Sarcophyton spp. set in 1 month after the onset of bleaching. Some colonies started to recover to some extent by the end of July, with 95% of the population of Sarcophyton spp. recovering by October. Both acute and chronic trials were conducted to determine whether temperature and/or salinity triggered bleaching. In the acute tests, Sarcophyton spp. at 40°C and salinity 20 psu were completely bleached, and death occurred after 57 and 204 h, respectively. However, the colonies at 40 psu could survive through the experimental trial. In the chronic tests, Sarcophyton spp. died when exposed to 34°C, whereas complete bleaching and mortality of Sarcophyton spp. occurred at salinities of 10 and 49 psu. We conclude that elevated temperatures had a greater effect on the bleaching of Sarcophyton spp. than did salinity.


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