Serum �-N-Acetylglucosaminidase Activity in Diabetic Patients during Conventional Therapy and during Treatment by Artificial Systems for Insulin Delivery

2015 ◽  
pp. 263-265
Author(s):  
D. Arena ◽  
A. Orlacchio ◽  
M. De Angelis ◽  
C. Maffei ◽  
P. Brunetti
Keyword(s):  
Conventional Therapy ◽  
Insulin Delivery ◽  
Diabetic Patients

730-P: At-Home Randomized Crossover Comparison of Automated Insulin Delivery vs. Conventional Therapy with Scheduled Meal Challenges

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 730-P
Author(s):  
JORDAN E. PINSKER ◽  
SUNIL DESHPANDE ◽  
MEI MEI CHURCH ◽  
MOLLY PIPER ◽  
CAMILLE C. ANDRE ◽  
...  
Keyword(s):  
Conventional Therapy ◽  
Insulin Delivery ◽  
Crossover Comparison ◽  
At Home

Injectable self-assembled peptide hydrogels for glucose-mediated insulin delivery

2018 ◽  
Vol 6 (6) ◽  
pp. 1480-1491 ◽  
Author(s):  
Mian Fu ◽  
Chenyu Zhang ◽  
Yuxuan Dai ◽  
Xue Li ◽  
Miaobo Pan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Closed Loop ◽  
Insulin Delivery ◽  
Diabetic Patients ◽  
Self Assembled ◽  
Peptide Hydrogels

Closed-loop glucose-responsive insulin delivery with excellent biocompatibility has the potential to improve the health and quality of life of diabetic patients.

scholarly journals Evaluations of knowledge, skills and practices of insulin storage and injection handling techniques of diabetic patients in Ethiopian primary hospitals

2020 ◽  
Author(s):  
Adeladlew Kassie Netere ◽  
Eyayaw Ashete ◽  
Eyob Alemayehu Gebreyohannes ◽  
Sewunet Admasu Belachew
Keyword(s):  
Insulin Therapy ◽  
Injection Site ◽  
Insulin Delivery ◽  
Cross Sectional Study ◽  
Injection Technique ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Knowledge Levels ◽  
Insulin Storage

Abstract Background: Insulin is an effective therapeutic agent in the management of diabetes but it is also sensitive to external environment. Consequently, diabetic patients’ adherence to insulin delivery recommendations is critical to its effectiveness. Lack of knowledge, skill, and irrational practices on appropriate insulin delivery techniques can result in therapeutic failure and increased costs of therapy. The aim of this study was to evaluate the knowledge, skills, and practices of insulin storage and injection technique of patients. Methods : An interview-based cross-sectional study was conducted in conveniently selected participants in Northwest Ethiopian primary hospitals from March 1 to May 30, 2019. Knowledge levels were assessed with right or wrong responses and practice was measured by administering a 4-point Likert scale structured questionnaire through face-to-face interviews. Finally, a five-point observational (demonstration) techniques checklist assessed patients’ skills. Results: Among 194 patients approached, 166 participants completed the survey with a response rate of 85.6 %. From these participants, 54.8% were males and the mean age was 38.46±13.8 years . The overall patients’ median knowledge and practice levels on insulin storage and handling techniques were moderately adequate (64.3%) and fair (55.4%), respectively. In patients’ skill assessments, 94.6% showed injection sites, 70% indicated injection site rotations, and 60.75% practiced injection site rotations. Education (p<0.001), duration of insulin therapy (p=0.008) and duration of diabetes (p=0.014) had a significant effect on patients’ knowledge level. Education (p<0.001), occupation (p<0.001), duration of insulin therapy (p=0.001), duration of diabetes (p=0.036) and patients’ knowledge levels (p<0.001) were found to have a significant effects on the patients’ practice level. A Mann-Whitney U test also disclosed that residency, ways to get insulin and mocked injection technique during first training had significant effects on patients’ knowledge levels. Conclusion: The current study revealed that patients had moderately adequate knowledge and fair practice levels on insulin storage and handling techniques. Moreover, patients missed important insulin administration skills. Healthcare professionals and stakeholders can play important roles in educating patients thereby improving the knowledge, practice, and administration techniques of patients.

scholarly journals Evaluations of knowledge, skills and practices of insulin storage and injection handling techniques of diabetic patients in Ethiopian primary hospitals

2020 ◽  
Author(s):  
Adeladlew Kassie Netere ◽  
Eyayaw Ashete ◽  
Eyob Alemayehu Gebreyohannes ◽  
Sewunet Admasu Belachew
Keyword(s):  
Insulin Therapy ◽  
Injection Site ◽  
Public Health Education ◽  
Insulin Delivery ◽  
Injection Technique ◽  
Diabetic Patients ◽  
Knowledge Level ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Insulin Storage

Abstract Background: Insulin is an effective therapeutic agent in the management of diabetes, but also sensitive to the external environment. Consequently, diabetic patients’ adherence to insulin delivery recommendations is critical for better effectiveness. Patients’ lack of knowledge, skill and irrational practices towards appropriate insulin delivery techniques may end up in therapeutic failure and increase costs of therapy. The aim of this study was to evaluate patients’ knowledge, skills and practices of insulin storage and injection techniques. Methods : An interview-based cross-sectional study was conducted through purposive selection of participants in Northwest Ethiopian primary hospitals from March 1 to May 30, 2019. Levels of knowledge were assessed with right or wrong responses, while practice was measured by using a 4-point Likert scale structured questionnaire collected via face-to-face interviews. Likewise, a five-point observational (demonstration) techniques checklist employed to assess patients’ skills. Results: Among 194 patients approached, 166 participants completed the survey giving a response rate of 85.6 %. More than half of the respondents (54.8%) were males and the mean age (±SD) was 38.5±13.8 years. The overall patients’ median knowledge and practice levels on insulin storage and handling techniques were moderately adequate (64.3%) and fair (55.4%), respectively. In patients’ skill assessments, 94.6% correctly showed injection sites, 70% indicated injection site rotations, and 60.75% practiced injection site rotations. Education (P<0.001 ), duration of insulin therapy (P=0.008), and duration of diabetes (P=0.014) had significant impact on knowledge level. Education (P <0.001), occupation (P<0.001), duration of insulin therapy (P=0.001), duration of diabetes (P =0.036) and patients’ knowledge level (P<0.001) were found to have a significant effects on the patients’ practice levels. A Mann-Whitney U test also disclosed that residency, ways to get insulin and mocked injection technique during the first training had significant effects on patients’ knowledge levels. Conclusion: The current study revealed that patients had moderately adequate knowledge and fair practice levels on insulin storage and handling techniques. However, patients missed important insulin administration skills. This study highlights the need of regular public health education so as to enhance the patients’ knowledge, skill and practice levels on insulin handling techniques.

Biodegradable phenylboronic acid-modified ε-polylysine for glucose-responsive insulin delivery via transdermal microneedles

2021 ◽  
Author(s):  
Di Shen ◽  
Haojie Yu ◽  
Li Wang ◽  
Xiang Chen ◽  
Jingyi Feng ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Phenylboronic Acid ◽  
Insulin Delivery ◽  
Diabetic Patients ◽  
Glucose Levels ◽  
Blood Glucose Levels

Microneedles with insulin-loaded glucose-responsive particles are promising to control the blood glucose levels of diabetic patients.

Metabolic effects of long-acting somatostatin analogue (sandostatin) in type I diabetic patients on conventional therapy

Diabetes ◽  
1989 ◽  
Vol 38 (6) ◽  
pp. 704-709 ◽  
Author(s):  
K. Osei ◽  
T. M. O'Dorisio ◽  
W. B. Malarkey ◽  
E. L. Craig ◽  
S. Cataland
Keyword(s):  
Conventional Therapy ◽  
Metabolic Effects ◽  
Diabetic Patients ◽  
Somatostatin Analogue ◽  
Type I ◽  
Long Acting
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