Animal Models of Tardive Dyskinesia: Their Use in the Search for New Treatment Methods

2015 ◽  
pp. 5-20 ◽  
Author(s):  
Christopher G. Goetz ◽  
Harold L. Klawans ◽  
Paul Carvey
Keyword(s):  
Animal Models ◽  
Tardive Dyskinesia ◽  
Treatment Methods ◽  
New Treatment

Animal Models

2018 ◽  
pp. 195-202
Author(s):  
Tadafumi Kato
Keyword(s):  
Animal Models ◽  
Mental Disorders ◽  
Neural Circuit ◽  
Chromosomal Abnormalities ◽  
Psychiatric Genetics ◽  
Genetic Animal Model ◽  
Animal Models Of Depression ◽  
Validity Criteria ◽  
New Treatment ◽  
Choice Of Species

Animal models of mental disorders are important for the development of new treatment and biomarkers. Animal models should satisfy three validity criteria. The choice of species used for animal models depends on the purposes of the study. There are several established models of chromosomal abnormalities for autism and schizophrenia. Stress-induced animal models of depression are controversial. There have been no established models for bipolar disorder, but the authors recently proposed a genetic animal model showing recurrent spontaneous depression-like episodes. Optogenetic manipulation of neural circuit is also used for modeling of mental disorders. Progress in psychiatric genetics will lead to the generation of valid animal models of psychiatric disorders.

New Treatment Methods for Waste Water Containing Chloride Ion Using Magnesium–Aluminum Oxide

2000 ◽  
Vol 29 (10) ◽  
pp. 1136-1137 ◽  
Author(s):  
Tomohito Kameda ◽  
Yoshinori Miyano ◽  
Toshiaki Yoshioka ◽  
Miho Uchida ◽  
Akitsugu Okuwaki
Keyword(s):  
Waste Water ◽  
Aluminum Oxide ◽  
Chloride Ion ◽  
Treatment Methods ◽  
New Treatment ◽  
Magnesium Aluminum Oxide

scholarly journals Vestibular implants studied in animal models: clinical and scientific implications

2016 ◽  
Vol 116 (6) ◽  
pp. 2777-2788 ◽  
Author(s):  
Richard F. Lewis
Keyword(s):  
Animal Models ◽  
Vestibular System ◽  
Animal Studies ◽  
Vestibular Function ◽  
Clinical Problem ◽  
Head Motion ◽  
The Past ◽  
New Treatment ◽  
Vestibular Damage ◽  
The Brain

Damage to the peripheral vestibular system can result in debilitating postural, perceptual, and visual symptoms. A potential new treatment for this clinical problem is to replace some aspects of peripheral vestibular function with an implant that senses head motion and provides this information to the brain by stimulating branches of the vestibular nerve. In this review I consider animal studies performed at our institution over the past 15 years, which have helped elucidate how the brain processes information provided by a vestibular (semicircular canal) implant and how this information could be used to improve the problems experienced by patients with peripheral vestibular damage.

Animal Models in Tardive Dyskinesia

2003 ◽  
pp. 245-266 ◽  
Author(s):  
Helen Rosengarten ◽  
Jack W. Schweitzer ◽  
Arnold J. Friedhofl
Keyword(s):  
Animal Models ◽  
Tardive Dyskinesia

scholarly journals Small animal models of heart failure

2019 ◽  
Vol 115 (13) ◽  
pp. 1838-1849 ◽  
Author(s):  
Christian Riehle ◽  
Johann Bauersachs
Keyword(s):  
Heart Failure ◽  
Animal Models ◽  
Surgical Techniques ◽  
Treatment Strategies ◽  
Small Animal ◽  
Therapeutic Strategies ◽  
Genetic Modifications ◽  
Small Animal Models ◽  
New Treatment ◽  
Underlying Mechanisms

Abstract Heart disease is a major cause of death worldwide with increasing prevalence, which urges the development of new therapeutic strategies. Over the last few decades, numerous small animal models have been generated to mimic various pathomechanisms contributing to heart failure (HF). Despite some limitations, these animal models have greatly advanced our understanding of the pathogenesis of the different aetiologies of HF and paved the way to understanding the underlying mechanisms and development of successful treatments. These models utilize surgical techniques, genetic modifications, and pharmacological approaches. The present review discusses the strengths and limitations of commonly used small animal HF models, which continue to provide crucial insight and facilitate the development of new treatment strategies for patients with HF.

Choline chloride in animal models of tardive dyskinesia

Life Sciences ◽  
1978 ◽  
Vol 22 (19) ◽  
pp. 1699-1707 ◽  
Author(s):  
Kenneth L. Davis ◽  
Leo E. Hollister ◽  
Adela L. Vento ◽  
Susan Simonton
Keyword(s):  
Animal Models ◽  
Tardive Dyskinesia ◽  
Choline Chloride

scholarly journals Relevance of animal models to human tardive dyskinesia

2012 ◽  
Vol 8 (1) ◽  
pp. 12 ◽  
Author(s):  
Pierre J Blanchet ◽  
Marie-Thérèse Parent ◽  
Pierre H Rompré ◽  
Daniel Lévesque
Keyword(s):  
Animal Models ◽  
Tardive Dyskinesia
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