Development of the Suprachiasmatic Nuclei and Other Circadian Pacemakers1

2015 ◽  
pp. 1-19
Author(s):  
Fred C. Davis
Keyword(s):  
Suprachiasmatic Nuclei

A QUANTITATIVE STUDY OF SPERMATOGENESIS IN RATS BEARING HYPOTHALAMIC LESIONS OF MAMMILLARY AND SUPRA-CHIASMATIC NUCLEI

1969 ◽  
Vol 60 (2) ◽  
pp. 276-280
Author(s):  
Bernard A. Rüedi
Keyword(s):  
Quantitative Analysis ◽  
Quantitative Study ◽  
Germinal Cell ◽  
Suprachiasmatic Nuclei ◽  
Hypothalamic Lesions ◽  
Cell Counts ◽  
Significant Change ◽  
Bilateral Lesions ◽  
Made In

ABSTRACT A quantitative analysis of spermatogenesis has been made in rats bearing bilateral lesions of the lateral mammillary nuclei or of the suprachiasmatic nuclei of the hypothalamus. There was no significant change in the germinal cell counts in lesioned rats as compared either with normal or with sham operated rats.

In Syrian and European hamsters, the duration of sensitive phase to light of the suprachiasmatic nuclei depends on the photoperiod

1996 ◽  
Vol 208 (1) ◽  
pp. 37-40 ◽  
Author(s):  
Patrick Vuillez ◽  
Nathalie Jacob ◽  
Rebecca Teclemariam-Mesbah ◽  
Paul Pévet
Keyword(s):  
Suprachiasmatic Nuclei ◽  
Sensitive Phase

scholarly journals General Anaesthesia Shifts the Murine Circadian Clock in a Time-Dependant Fashion

2021 ◽  
Vol 3 (1) ◽  
pp. 87-97
Author(s):  
Nicola M. Ludin ◽  
Alma Orts-Sebastian ◽  
James F. Cheeseman ◽  
Janelle Chong ◽  
Alan F. Merry ◽  
...  
Keyword(s):  
Circadian Clock ◽  
General Anaesthesia ◽  
Wheel Running ◽  
Phase Shifts ◽  
Time Dependent ◽  
Suprachiasmatic Nuclei ◽  
Response Curves ◽  
Inhalational Anaesthetic ◽  
Locomotor Rhythms ◽  
Time Dependent Analysis

Following general anaesthesia (GA), patients frequently experience sleep disruption and fatigue, which has been hypothesized to result at least in part by GA affecting the circadian clock. Here, we provide the first comprehensive time-dependent analysis of the effects of the commonly administered inhalational anaesthetic, isoflurane, on the murine circadian clock, by analysing its effects on (a) behavioural locomotor rhythms and (b) PER2::LUC expression in the suprachiasmatic nuclei (SCN) of the mouse brain. Behavioural phase shifts elicited by exposure of mice (n = 80) to six hours of GA (2% isoflurane) were determined by recording wheel-running rhythms in constant conditions (DD). Phase shifts in PER2::LUC expression were determined by recording bioluminescence in organotypic SCN slices (n = 38) prior to and following GA exposure (2% isoflurane). Full phase response curves for the effects of GA on behaviour and PER2::LUC rhythms were constructed, which show that the effects of GA are highly time-dependent. Shifts in SCN PER2 expression were much larger than those of behaviour (c. 0.7 h behaviour vs. 7.5 h PER2::LUC). We discuss the implications of this work for understanding how GA affects the clock, and how it may inform the development of chronotherapeutic strategies to reduce GA-induced phase-shifting in patients.

Bilateral Lesions of the Suprachiasmatic Nuclei Alter the Nocturnal Melatonin Secretion in Sheep

1995 ◽  
Vol 7 (2) ◽  
pp. 145-152 ◽  
Author(s):  
A. Tessonneaud ◽  
A. Locatelli ◽  
M. Caldani ◽  
M. C. Viguier-Martinez
Keyword(s):  
Suprachiasmatic Nuclei ◽  
Melatonin Secretion ◽  
Bilateral Lesions

scholarly journals The impact of temporal modulations in irradiance under light adapted conditions on the mouse suprachiasmatic nuclei (SCN)

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Rachel Dobb ◽  
Franck Martial ◽  
Daniel Elijah ◽  
Riccardo Storchi ◽  
Timothy M. Brown ◽  
...  
Keyword(s):  
Suprachiasmatic Nuclei ◽  
The Impact

Neuropeptide Y in the Ventromedial and Suprachiasmatic Nuclei: Role in the Feeding Pattern of Monosodium Glutamate-Treated Rats

1998 ◽  
Vol 1 (3) ◽  
pp. 183-189 ◽  
Author(s):  
Alain Stricker-Krongrad ◽  
Arlette Burlet ◽  
Jean-Pierre Nicolas ◽  
Claude Burlet ◽  
Bernard Beck
Keyword(s):  
Neuropeptide Y ◽  
Monosodium Glutamate ◽  
Feeding Pattern ◽  
Suprachiasmatic Nuclei

scholarly journals Multiplexing Visual Signals in the Suprachiasmatic Nuclei

Cell Reports ◽  
2017 ◽  
Vol 21 (6) ◽  
pp. 1418-1425 ◽  
Author(s):  
Adam R. Stinchcombe ◽  
Joshua W. Mouland ◽  
Kwoon Y. Wong ◽  
Robert J. Lucas ◽  
Daniel B. Forger
Keyword(s):  
Visual Signals ◽  
Suprachiasmatic Nuclei
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