Infectious Primate Type C Virus Group: Evidence for an Origin from an Endogenous Virus of the Rodent, Mus caroli

2015 ◽  
pp. 115-120
Author(s):  
George J. Todaro ◽  
Raoul E. Benveniste ◽  
Charles J. Sherr ◽  
Michael M. Lieber ◽  
Robert Callahan
Keyword(s):  
Endogenous Virus ◽  
Virus Group ◽  
Mus Caroli ◽  
Type C

scholarly journals Isolation from the asian mouse Mus caroli of an endogenous type C virus related to infectious primate type C viruses.

1975 ◽  
Vol 72 (6) ◽  
pp. 2315-2319 ◽  
Author(s):  
M. M. Lieber ◽  
C. J. Sherr ◽  
G. J. Todaro ◽  
R. E. Benveniste ◽  
R. Callahan ◽  
...  
Keyword(s):  
Mus Caroli ◽  
Type C

A rapid direct radioimmunoassay for type C virus group-specific antigen and antibody

Virology ◽  
1972 ◽  
Vol 50 (1) ◽  
pp. 294-296 ◽  
Author(s):  
Stephen Oroszlan ◽  
Martin M.H. White ◽  
Raymond V. Gilden ◽  
Howard P. Charman
Keyword(s):  
Specific Antigen ◽  
Virus Group ◽  
Type C

scholarly journals Novel Endogenous Type C Retrovirus in Baboons: Complete Sequence, Providing Evidence for Baboon Endogenous Virusgag-pol Ancestry

1999 ◽  
Vol 73 (8) ◽  
pp. 7021-7026 ◽  
Author(s):  
Rui Mang ◽  
Jaap Goudsmit ◽  
Antoinette C. van der Kuyl
Keyword(s):  
Genomic Library ◽  
Endogenous Retrovirus ◽  
Complete Sequence ◽  
Gene Organization ◽  
Primer Binding Site ◽  
Papio Cynocephalus ◽  
Coding Region ◽  
Endogenous Virus ◽  
Type D ◽  
Type C

ABSTRACT A complete endogenous type C viral genome has been isolated from a baboon genomic library. The provirus, Papio cynocephalusendogenous retrovirus (PcEV), is 8,572 nucleotides long, and 38 to 59 proviral copies per baboon genome are found. The PcEV provirus possesses the typical simple retroviral gene organization, including two long terminal repeats and genes encoding gag, pol, and env proteins. The open reading frames for gag-pol andenv are complete but have premature stop codons or frameshift mutations. The primer binding site of PcEV is complementary to tRNAGly. The gag and pol genes of PcEV are closely related to those of the baboon endogenous virus (BaEV). The env coding region of PcEV is related to theenv genes of type C retroviruses. This suggests that PcEV is one of the ancestors of BaEV contributing the type Cgag-pol genome fragment to the type C/D recombinant virus BaEV. Earlier it was shown that another endogenous type D virus (simian endogenous retrovirus) provided the env gene for BaEV (A. C. van der Kuyl et al., J. Virol. 71:3666–3676, 1997).

Multiple Distinct Antigenic Determinants Associated with Murine Type-C Virus Group-Specific Antigen

Intervirology ◽  
1973 ◽  
Vol 2 (5-6) ◽  
pp. 326-336 ◽  
Author(s):  
James Davis ◽  
Howard P. Charman ◽  
Stephen Oroszlan ◽  
Raymond V. Gilden
Keyword(s):  
Specific Antigen ◽  
Antigenic Determinants ◽  
Virus Group ◽  
Type C

scholarly journals Identification of the Myelin Protein Plasmolipin as the Cell Entry Receptor for Mus caroli Endogenous Retrovirus

2008 ◽  
Vol 82 (14) ◽  
pp. 6862-6868 ◽  
Author(s):  
A. Dusty Miller ◽  
Ulla Bergholz ◽  
Marion Ziegler ◽  
Carol Stocking
Keyword(s):  
Cell Line ◽  
Hybrid Cell ◽  
Receptor Gene ◽  
Wild Mouse ◽  
Cell Types ◽  
Mouse Cell ◽  
Endogenous Retrovirus ◽  
Receptor Activity ◽  
Endogenous Virus ◽  
Mus Caroli

ABSTRACT The Asian wild mouse species Mus caroli harbors an endogenous retrovirus (McERV) that is closely related to but distinct from the endogenous retrovirus family defined by the Mus dunni endogenous virus and the Mus musculus endogenous retrovirus. McERV could infect some cell types from humans, dogs, and rats, but not all, and did not infect any mouse cell line tested. Because of its interesting host range and proposed ancestral relationship to primate retroviruses and because none of the entry receptors for this family of retroviruses had been identified, we began a search for the McERV receptor. We determined the chromosomal location of the receptor gene in the human genome by phenotypic screening of the G3 human-hamster radiation hybrid cell line panel and confirmed the localization by assaying for receptor activity conferred by bacterial artificial chromosome (BAC) clones spanning the region. We next localized the gene more precisely in one positive BAC by assaying for receptor activity following BAC digestion with several restriction enzymes that cleaved different sets of genes, and we confirmed that the final candidate gene, plasmolipin (PLLP; TM4SF11), is the novel receptor by showing that the expression of the human PLLP cDNA renders hamster and mouse cells susceptible to McERV infection. PLLP functions as a voltage-dependent potassium ion channel and is expressed primarily in kidney and brain, helping to explain the limited range of cell types that McERV can infect. Interestingly, mouse PLLP also functioned well as a receptor for McERV but was simply not expressed in the mouse cell types that we originally tested.

scholarly journals Discovery of a New Endogenous Type C Retrovirus (FcEV) in Cats: Evidence for RD-114 Being an FcEVGag-Pol/Baboon Endogenous Virus BaEVEnv Recombinant

1999 ◽  
Vol 73 (10) ◽  
pp. 7994-8002 ◽  
Author(s):  
Antoinette C. van der Kuyl ◽  
John T. Dekker ◽  
Jaap Goudsmit
Keyword(s):  
De Novo ◽  
Germ Line ◽  
Endogenous Retrovirus ◽  
Domestic Cat ◽  
Papio Cynocephalus ◽  
Endogenous Virus ◽  
Dna Library ◽  
Genomic Dna Library ◽  
Type C ◽  
Baboon Endogenous Virus

ABSTRACT Analysis of a cat genomic DNA library showed that cats harbor a previously unrecognized endogenous type C retrovirus, whoseenv gene has homology to the murine Fv-4resistance gene. This unique retrovirus, designated FcEV (Felis catus endogenous retrovirus), has a type C pol gene, closely related to the primate Papio cynocephalusendogenous virus (PcEV) pol, not overlapping theenv gene, unlike in other type C retroviruses, and is presumably present in a higher copy number than RD-114. Phylogenetic analysis of FcEV and RD-114 fragments amplified from cat species and comparison with baboon endogenous virus (BaEV) fragments from monkeys suggested that RD-114 does not represent the cat strain of BaEV but is actually a new recombinant between FcEV type C genes and theenv gene of BaEV. Although BaEV did appear to have infected an ancestor of the domestic cat lineage, it was a de novo recombinant that made its way into the cat germ line.

Infection of human teratocarcinoma cell lines by a type C primate retrovirus (baboon endogenous virus)

1982 ◽  
Vol 133 (4) ◽  
pp. 483-488 ◽  
Author(s):  
F. Saal ◽  
F. Cavalieri ◽  
A. Samso ◽  
R. Emanoil-Ravicovitch ◽  
J. Périès
Keyword(s):  
Cell Lines ◽  
Endogenous Virus ◽  
Teratocarcinoma Cell ◽  
Type C ◽  
Baboon Endogenous Virus
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