Do Actinic Keratoses and Superficial Squamous Cell Carcinomas Have a Specific Immunoprofile?

Author(s):  
James W. Wells
2010 ◽  
Vol 10 (S1) ◽  
Author(s):  
U Bottoni ◽  
T Vitagliano ◽  
F G Amoruso ◽  
M Greco ◽  
M A Fiorillo

2002 ◽  
Vol 6 (3) ◽  
pp. 207-209 ◽  
Author(s):  
D. Czarnecki ◽  
C. J. Meehan ◽  
F. Bruce ◽  
G. Culjak

Background: Retrospective studies have given conflicting results with respect to how many cutaneous squamous cell carcinomas (SCCs) arise in actinic keratoses (AK). Objective: This study was conducted to determine what percentage of SCCs arise in AKs and to obtain more information about two histological features of SCCs, namely, thickness and ulceration. Methods: A prospective study was done of all SCCs treated by the authors during one calendar year. Results: Two hundred eight patients with SCC were entered into the study. An AK was contiguous with an SCC in 72% of the cases. This was taken as evidence that the SCC arose in the AK. Men presented with thicker and more ulcerated SCCs than women, but these were not statistically significant: p = 0.06 for thickness and p = 0.07 for ulceration. Ulcerated SCCs were more likely to arise on the head and neck (p = 0.02), on patients who had multiple skin cancers ( p = 0.005), and on patients who had a family history of skin cancer ( p = 0.03). Conclusion: Actinic keratoses need to be removed before they turn into SCCs. The prognostic significance of ulceration of cutaneous SCCs needs to be determined.


2019 ◽  
Vol 10 ◽  
Author(s):  
Elizabeth S. Borden ◽  
Paul Kang ◽  
Heini M. Natri ◽  
Tanya N. Phung ◽  
Melissa A. Wilson ◽  
...  

2004 ◽  
Vol 30 (10) ◽  
pp. 1299-1302 ◽  
Author(s):  
David A. Wrone ◽  
Stephen Yoo ◽  
Lisa K. Chipps ◽  
Ronald L. Moy

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