scholarly journals Neuroendocrine Tumors of the Bronchopulmonary System (Typical and Atypical Carcinoid Tumors): Current Strategies in Diagnosis and Treatment. Conclusions of an Expert Meeting February 2011 in Weimar, Germany

2014 ◽  
Vol 37 (5) ◽  
pp. 5-5 ◽  
Author(s):  
Dieter Hörsch ◽  
Kurt W. Schmid ◽  
Martin Anlauf ◽  
Kaid Darwiche ◽  
Tim Denecke ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Carcinoid Tumors ◽  
Diagnosis And Treatment ◽  
Atypical Carcinoid ◽  
Weimar Germany ◽  
Expert Meeting

scholarly journals Case report of atypical carcinoid tumors of the larynx

2018 ◽  
Vol 5 (9) ◽  
pp. 4155
Author(s):  
Fatimah S. Alkhaliah ◽  
Ibrahim A. Almajed ◽  
Anwar S. Alkhalifah ◽  
Abdulltaif S. Alkhalifah ◽  
Khalid A. AlYahya ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Neuroendocrine Tumors ◽  
Histopathological Examination ◽  
Small Cell ◽  
Carcinoid Tumors ◽  
High Rate ◽  
Atypical Carcinoid ◽  
Typical Carcinoid ◽  
Laryngeal Tumors

Neuroendocrine tumors (NET) of the larynx are considered one of the rare disease; they represent only 1% of the laryngeal tumors. These tumors are very aggressive with a high rate of metastases. Diagnosis is done by computed tomography and confirmed by histopathological examination. Neuroendocrine tumors can be classified into four types based on histopathology: typical carcinoid tumors, atypical carcinoid tumors, small cell neuroendocrine tumors and paragangliomas. Atypical carcinoid tumor of the larynx is considered rare in occurrence. We report a rare laryngeal neuroendocrine tumor case.

scholarly journals Typical and Atypical Carcinoid Tumors of the Lung Are Characterized by 11q Deletions as Detected by Comparative Genomic Hybridization

1998 ◽  
Vol 153 (4) ◽  
pp. 1089-1098 ◽  
Author(s):  
Axel K. Walch ◽  
Horst F. Zitzelsberger ◽  
Michaela M. Aubele ◽  
Anita E. Mattis ◽  
Manfred Bauchinger ◽  
...  
Keyword(s):  
Comparative Genomic Hybridization ◽  
Carcinoid Tumors ◽  
Comparative Genomic ◽  
Atypical Carcinoid ◽  
Genomic Hybridization

scholarly journals Molecular Pathology of Well-Differentiated Pulmonary and Thymic Neuroendocrine Tumors: What Do Pathologists Need to Know?

2021 ◽  
Vol 32 (1) ◽  
pp. 154-168 ◽  
Author(s):  
Marco Volante ◽  
Ozgur Mete ◽  
Giuseppe Pelosi ◽  
Anja C. Roden ◽  
Ernst Jan M. Speel ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Young Patients ◽  
Carcinoid Tumors ◽  
Neuroendocrine Neoplasms ◽  
Grey Zone ◽  
Cell Hyperplasia ◽  
Ki 67 ◽  
Familial Form ◽  
Well Differentiated ◽  
Neuroendocrine Carcinomas

AbstractThoracic (pulmonary and thymic) neuroendocrine tumors are well-differentiated epithelial neuroendocrine neoplasms that are classified into typical and atypical carcinoid tumors based on mitotic index cut offs and presence or absence of necrosis. This classification scheme is of great prognostic value but designed for surgical specimens, only. Deep molecular characterization of thoracic neuroendocrine tumors highlighted their difference with neuroendocrine carcinomas. Neuroendocrine tumors of the lung are characterized by a low mutational burden, and a high prevalence of mutations in chromatin remodeling and histone modification-related genes, whereas mutations in genes frequently altered in neuroendocrine carcinomas are rare. Molecular profiling divided thymic neuroendocrine tumors into three clusters with distinct clinical outcomes and characterized by a different average of copy number instability. Moreover, integrated histopathological, molecular and clinical evidence supports the existence of a grey zone category between neuroendocrine tumors (carcinoid tumors) and neuroendocrine carcinomas. Indeed, cases with well differentiated morphology but mitotic/Ki-67 indexes close to neuroendocrine carcinomas have been increasingly recognized. These are characterized by specific molecular profiles and have an aggressive clinical behavior. Finally, thoracic neuroendocrine tumors may arise in the background of genetic susceptibility, being MEN1 syndrome the well-defined familial form. However, pathologists should be aware of rarer germline variants that are associated with the concurrence of neuroendocrine tumors of the lung or their precursors (such as DIPNECH) with other neoplasms, including but not limited to breast carcinomas. Therefore, genetic counseling for all young patients with thoracic neuroendocrine neoplasia and/or any patient with pathological evidence of neuroendocrine cell hyperplasia-to-neoplasia progression sequence or multifocal disease should be considered.

Protocol for the Examination of Specimens From Patients With Neuroendocrine Tumors (Carcinoid Tumors) of the Appendix

2010 ◽  
Vol 134 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Mary Kay Washington ◽  
Laura H. Tang ◽  
Jordan Berlin ◽  
Philip A. Branton ◽  
Lawrence J. Burgart ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Carcinoid Tumors

scholarly journals Clinical features and outcomes of gastric neuroendocrine tumors after endoscopic diagnosis and treatment

Medicine ◽  
2018 ◽  
Vol 97 (38) ◽  
pp. e12101 ◽  
Author(s):  
Chen-Shuan Chung ◽  
Cho-Lun Tsai ◽  
Yin-Yi Chu ◽  
Kuan-Chih Chen ◽  
Jung-Chun Lin ◽  
...  
Keyword(s):  
Clinical Features ◽  
Neuroendocrine Tumors ◽  
Endoscopic Diagnosis ◽  
Diagnosis And Treatment

Typical and atypical carcinoid tumors of the lung: a clinicopathological correlation of 783 cases with emphasis on histological features

2020 ◽  
Vol 98 ◽  
pp. 98-109
Author(s):  
Cesar A. Moran ◽  
Kaleigh E. Lindholm ◽  
Hans Brunnström ◽  
Gerald Langman ◽  
Se Jin Jang ◽  
...  
Keyword(s):  
Carcinoid Tumors ◽  
Clinicopathological Correlation ◽  
Atypical Carcinoid ◽  
Histological Features
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