Prospective Clinical and Epidemiologic Study of Vulvar Lichen Sclerosus: Analysis of Prevalence and Severity of Clinical Features, together with Historical and Demographic Associations

Dermatology ◽  
2014 ◽  
Vol 228 (2) ◽  
pp. 145-151 ◽  
Author(s):  
Annarosa Virgili ◽  
Alessandro Borghi ◽  
Giulia Toni ◽  
Sara Minghetti ◽  
Monica Corazza
Keyword(s):  
Clinical Features ◽  
Epidemiologic Study ◽  
Lichen Sclerosus ◽  
Vulvar Lichen Sclerosus

scholarly journals Etiology, Clinical Features, and Diagnosis of Vulvar Lichen Sclerosus: A Scoping Review

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Nilanchali Singh ◽  
Prafull Ghatage
Keyword(s):  
Clinical Features ◽  
Scoping Review ◽  
English Language ◽  
Lichen Sclerosus ◽  
Published Data ◽  
Inflammatory Disorder ◽  
Lichen Sclerosus Et Atrophicus ◽  
Chronic Inflammatory Disorder ◽  
Study Selection ◽  
Vulvar Lichen Sclerosus

Objective. Vulvar lichen sclerosus (VLS) is a chronic inflammatory disorder, which affects women of all ages. With numerous controversies as regards to the nomenclature, diagnosis and its association with neoplastic conditions, we decided to conduct a scoping review on this subject. Data Source. A review protocol was developed, and the Knowledge Resource Services website was used to do a search of articles pertaining to VLS with keywords “Vulvar,” “Vulval,” “diagnosis,” “lichen sclerosus et atrophicus,” “kraurosis,” “vulvar dystrophy,” and “Lichen Sclerosus”. Study Selection. The search was limited to published data from the last ten years, i.e., from July 2009 onwards and in the English language. A total of 338 articles pertaining to VLS were obtained. Older data were accessed if particular information was sought for. Results & Conclusion. The presentation is bimodal, i.e., one in prepubertal girls (average age: 7.6 years) and the other in peri- and postmenopausal women (average age: 52.6 years). However, many cases also present during reproductive years. Studies suggest a multifactorial origin as far as etiology is concerned, including a genetic, autoimmune, hormonal, and local infectious background. It affects the genital labial, perineal, and perianal areas and manifests as a patchy, thin, glistening, ivory-white area. Diagnosis is mainly based on clinical features. Biopsy is seldom required. It has been well established as a precursor lesion of dVIN and vulvar carcinoma.

Cell cycle proteins as molecular markers of malignant change in vulvar lichen sclerosus

2001 ◽  
Vol 11 (2) ◽  
pp. 113-118 ◽  
Author(s):  
K. J. Rolfe ◽  
L. J. Eva ◽  
A. B. Maclean ◽  
J. C. Crow ◽  
C. W. Perrett ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Molecular Markers ◽  
Lichen Sclerosus ◽  
Malignant Change ◽  
Cell Cycle Proteins ◽  
Vulvar Lichen Sclerosus

scholarly journals 310 A new proposal for the clinical classification of vulvar lichen sclerosus: an observational prospective study

2020 ◽  
Author(s):  
Veronica Boero ◽  
Carlo A Liverani ◽  
Massimiliano Brambilla ◽  
Ermelinda Monti ◽  
Filippo Murina ◽  
...  
Keyword(s):  
Prospective Study ◽  
Lichen Sclerosus ◽  
Clinical Classification ◽  
Observational Prospective Study ◽  
Vulvar Lichen Sclerosus

Clearance in vulvar lichen sclerosus: a realistic treatment endpoint or a chimera?

2017 ◽  
Vol 32 (1) ◽  
pp. 96-101 ◽  
Author(s):  
A. Borghi ◽  
A. Virgili ◽  
S. Minghetti ◽  
G. Toni ◽  
M. Corazza
Keyword(s):  
Lichen Sclerosus ◽  
Treatment Endpoint ◽  
Vulvar Lichen Sclerosus

Vulvar lichen sclerosus

2021 ◽  
Vol 8_2021 ◽  
pp. 160-165
Author(s):  
Surkichin S.I. Surkichin ◽  
Kruglova L.S. Kruglova ◽  
Apolikhina I.A. Apolikhina ◽  
◽  
◽  
...  
Keyword(s):  
Lichen Sclerosus ◽  
Vulvar Lichen Sclerosus
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